Effects of Hormone Replacement Therapy and Aging on Cognition: Evidence for Executive Dysfunction

ABSTRACT

The present study was designed to explore whether the frontal lobe hypothesis of cognitive aging may be extended to describe the cognitive effects associated with estrogen use in postmenopausal women. Postmenopausal estrogen-only users, estrogen + progesterone users, and non-users (60–80 years old), as well as young, regularly cycling women (18–30 years old) completed an item and source memory task. Since source memory is thought to rely more on executive processes than item memory, we hypothesized that aging and estrogen effects would be greater for source memory than for item memory. Neuropsychological tests explored whether the effects of aging and estrogen use were revealed on other tests of frontal lobe function. Results from the experimental task revealed greater aging and estrogen effects for source memory than for item memory, and neuropsychological results revealed aging and estrogen effects on a subset of tests of executive function. Women on estrogen + progesterone therapy did not outperform non-users, suggesting that the addition of progesterone to hormone therapy may mitigate the benefits induced by estrogen use alone. Overall, findings support the hypothesis that estrogen use may temper age-related cognitive decline by helping to maintain functions subserved by the frontal lobes.     

Age- and education-adjusted normative data for the Montreal Cognitive Assessment (MoCA) in older adults age 70–99

The original validation study for the Montreal Cognitive Assessment (MoCA) suggests a cutoff score of 26; however, this may be too stringent for older adults, particularly for those with less education. Given the rapidly increasing number of older adults and associated risk of dementia, this study aims to provide appropriate age- and education-adjusted norms for the MoCA. Data from 205 participants in an ongoing longevity study were used to derive normative data. Individuals were grouped based on age (70–79, 80–89, 90–99) and education level (≤12 Years, 13–15, ≥16 Years). There were significant differences between age and education groups with younger and more educated participants outperforming their counterparts. Forty-six percent of our sample scored below the suggested cutoff of 26. These normative data may provide a more accurate representation of MoCA performance in older adults for specific age and education stratifications.     

Age-related effects of blood pressure on everyday cognitive function in community-dwelling women

ABSTRACT

Objectives: Blood pressure is an indicator of vascular health that has been associated with cognition and quality of life in older age. Few studies have examined blood pressure across everyday cognitive tasks, which may have superior predictive functional utility than traditional cognitive measures. We explored blood pressure as a predictor of everyday problem solving (EPS) performance in middle-aged and older women. Method: Community-dwelling women (age: 51–91) with low-normal blood pressure to mild hypertension underwent traditional and everyday cognitive testing. EPS was determined by the number of safe/effective solutions generated for real-world scenarios. Results: Analyses revealed that lower systolic blood pressure and pulse pressure were associated with worse EPS ability after controlling for age, education, and traditional cognitive abilities. Discussion: These results support that blood pressure may be an important predictor of everyday cognitive abilities in older age. Potential implications for real-world functioning are discussed.     

Excluding exclusion: the natural(istic) dualist approach

The exclusion problem for mental causation is one of the most discussed puzzles in the mind–body literature. There has been a general agreement among philosophers, especially because most of them are committed to some form of physicalism, that the dualist cannot escape the exclusion problem. I argue that a proper understanding of dualism – its form, commitments, and intuitions – makes the exclusion problem irrelevant from a dualist perspective. The paper proposes a dualist approach, based on a theory of event causation, according to which events are medium-grained, namely parsed into mental and physical property components. A theory of contrastive mental causation is built upon this theory of events, for which the problem of exclusion does not arise.     

‘He thinks Krishna is his friend’: Domestic space and temple sociality in the socialisation beliefs of immigrant Indian Hindu parents

This paper reports results from a study of the cultural belief systems, or ethnotheories, of Asian Indian Hindu parents in the city of Baltimore, Maryland, in the USA. I adopted a cultural, developmental psychological approach and, over a one-year period, used caregiver diaries, ecological inventories, repeated in-depth interviews and participant observations to gain access to the ethnotheories of the parents. These immigrant parents emphasised family ties, unprompted adherence to the daily routine, knowledge of cultural origins and religiously inflected moral values. Exploring the nuances of their emphasis on cultural origins and moral and religious values, particularly as those relate to Hinduism and its transnational rearticulation, I show how the parents utilised domestic spaces and the temple as dual venues to systematically socialise their children into a new form of Hindu religious and ‘Indian’ ethnic identity in the USA.     

The relationship between quantity,type, and timing of external childcare and child problem behaviour in Switzerland

This study aimed to investigate the relationship between external childcare and child problem behaviour at age 7 in a culturally diverse urban sample from Switzerland. We used data from the Zurich Project on the Social Development of Children and Youths (z-proso). Findings suggested that the quantity of group-based childcare (but not individual childcare) was related to aggression, ADHD, non-aggressive externalizing behaviour, and anxiety and depression at age 7. Analyses on timing of childcare suggested that the accumulation of childcare over the life course, and not so much childcare in the first years of life, was associated with child problem behaviour. In addition, childcare at age 5 to 7 had a unique relationship with problem behaviour over and above quantity of group-based childcare received in other age periods.     

Girls' and boys' perception of mothers' intentions of using physical punishment and reasoning as discipline methods

The aim of this study was to examine Swedish children's perceptions of mothers' intentions of using physical punishment and reasoning, as well as their evaluations of the mothers as being good parents. Six- to nine-year-old children were interviewed. Children's evaluations as well as reports of mothers' intentions varied according to the type of vignette presented (discipline in response to child aggression, or in response to child non-compliance), and their own parents' childrearing attitudes. Children who said that mothers who use physical punishment were “good mothers” were more likely to have parents with more traditional childrearing attitudes, and were older. Older children also evaluated mother's use of reasoning, and perceived greater intentionality in this form of discipline, compared to younger children. No gender differences were found either for perception of intention or evaluation of the mother.     

Does timeframe adjustment of the Life Orientation Test-Revised assess optimism as a state?

ABSTRACT

Optimism is prospectively associated with superior health outcomes in cardiac patients, making it an attractive target for well-being interventions in this population. However, optimism measured by the Life Orientation Test-Revised (LOT-R) has largely been considered a static, dispositional construct. Among 125 patients with a recent acute coronary syndrome who received a positive psychology intervention, we assessed the properties of a modified LOT-R that changed the timeframe of items from general dispositional statements to queries about ‘right now.’ We aimed to learn whether this modified LOT-R was more dynamic than the original LOT-R via administration of both instruments at three timepoints over the 16-week study period. Contrary to our hypothesis, this modified LOT-R showed no greater change in mean score or intra-individual variance than the original LOT-R over 16 weeks. This suggests that simply changing the timeframe of the LOT-R may not facilitate assessment of more state-like optimism in medical patients.     

Hope and world survival

Abstract

Gives an overview and analysis of the role of the Pacific region in the world economy stressing the ongoing shift of growth potential and purchasing power. Japan's surplus is discussed as a tool to stimulate economic growth in the world. Trends in Pacific cooperation are given.     

Summary and Recommendation

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