试论中医基础研究中的创造性思维

创造性思维对于中医基础研究非常重要.在中医基础研究中过分依赖高新技术,或者不敢直面问题、遇到困难退缩将阻碍创造性思维.中医基础研究的创造性思维需要研究者在传统知识、现代知识、高新技术与仪器等方面作好充分的准备.为使研究保持正确的方向,在研究中要处理好"已知"与"未知"的关系并以"和"的态度对待学术争论.     

The Effects of Early English Learning on Auditory Perception of English Minimal Pairs by Taiwan University Students

Auditory perception of English minimal pairs was tested with or without noise background. Each subject was interviewed after the test to collect information regarding their early experience on learning English as a foreign language. This study was designed to examine the differential effects of learning English at three age-starting points and two learning durations. This study hopes to determine how childhood experience of English learning (which is not mandatory in public elementary schools) has affected the auditory competence of university students in distinguishing English minimal pairs. Results showed that age effects were salient only under condition of noise background. Without the interference of background noise, most subjects performed well enough to obliterate any potential differences.     

先秦音乐与儒家的礼乐理想

中国古代音乐的基本理论在先秦时期已初具系统。从音律上看,先秦音乐与现代音乐或西方古代音乐不存在本质上的不同,但在音阶的选用上,人们把“五声”视为最理想的音阶,所追求的音乐意念是“和”。先秦儒家在继承周代礼乐制度的基础上提出了“礼以别宜、乐以敦和”的礼乐理想作为治国平天下的基本途径,不仅使礼乐之间的互补关系得到进一步发展,还使“乐”的含义发生了深刻的转化。所谓乐,不仅指声音的和谐,更重要的是内心的愉悦,即“无声之乐”。它所强调的是个人对差别性社会规范即礼的发自内心的认同,并从生活践履中获得和乐的内在体验。     

The construction of large number representations in adults

What is the nature of our mental representation of quantity? We find that human adults show no performance cost of comparing numerosities across vs. within visual and auditory stimulus sets, or across vs. within simultaneous and sequential sets. In addition, reaction time and performance in such tasks are determined by the ratio of the numerosities to be compared; absolute set size has no effect. These findings suggest that modality-specific stimulus properties undergo a non-iterative transformation into representations of quantity that are independent of the modality or format of the stimulus.     

Obstructive sleep apnea syndrome: autobiographical memory predicts the course of depressive affect after nCPAP therapy

Although nCPAP therapy has proven to be efficient at removing symptoms of obstructive sleep apnea syndrome (OSAS), recovery from depression frequently remains unsatisfactory. Other studies have shown that recall of autobiographical memories (AM) is a psychological vulnerability marker for depression, and also have shown its predictive power for the course of depression. It is therefore hypothesized that AM also predict the course of depressive affect in OSAS patients. Fifty-four consecutively admitted OSAS patients received standard nCPAP therapy. Specificity of AM assessed at the beginning of treatment was used as a predictor in a regression analysis, and the extent of recovery from depression over a follow-up period of between six to nine weeks served as the criterion variable. The results supported the hypothesis that patients who were able to recall more specific AM in response to positively valenced cue words showed a more substantial recovery from depression. This has important treatment implications.     

An ERP study of sensory mismatch expressions in Japanese

Combinations of different sensory words produce mismatch expressions like smooth color and red touch in contrast to normal expressions like red color and smooth touch. Concerning these sensory mismatch expressions, results of three experiments are reported. Experiment 1 revealed that (i) mismatch expressions were less comprehensible than normal expressions, and that (ii) there were two patterns among mismatch expressions: the high-comprehensible mismatch expression (HighCME, e.g., smooth color) and the low-comprehensible mismatch expression (LowCME, e.g., red touch). Experiment 2 revealed that the mismatch expressions produced a significantly greater N400 amplitude than the normal expressions. Experiment 3 implied that the difference between High/LowCME was reflected in a later latency band or in a topographical difference of N400, although the statistical significance was marginal. It is argued that the processes to integrate linguistic elements (e.g., combining adjectives and nouns) are not homogeneous.     

Septal infusions of glucose or pyruvate,but not fructose,produce avoidance deficits when co-infused with the GABA agonist muscimol

Although glucose typically enhances memory or reverses memory deficits, glucose can also produce memory deficits when co-infused with the gamma-aminobutyric acid (GABA) agonist muscimol into the medial septum (Parent & Gold, 1997; Parent, Laurey, Wilkniss, & Gold, 1997). To date the mechanisms underlying the memory-impairing interaction between GABA and glucose remain unknown. Here we investigate whether this effect is the result of hyperosmolar conditions or may involve glucose metabolism. Male Sprague-Dawley rats were given one-trial inhibitory avoidance training after receiving septal infusions of vehicle (phosphate-buffered saline, 0.5 microl), the GABA(A) agonist muscimol (3 nmol), glucose (16.5, 33, or 66 nmol), fructose (33 nmol), pyruvate (33 nmol), or a solution containing muscimol combined with glucose, fructose, or pyruvate. Retention performance was tested 48 h later. Infusions of glucose, pyruvate, fructose, or muscimol alone did not affect retention performance. However, co-infusions of all doses of glucose (16.5, 33, or 66 nmol) or the glycolytic end product pyruvate with muscimol impaired retention performance. Co-infusions of fructose with muscimol did not affect retention performance. These results suggest that the memory-impairing interaction between glucose and muscimol does not result from hyperosmolar conditions, because equiosmolar concentrations of fructose do not mimic the effects of glucose and the memory deficits do not vary as a function of glucose concentration. The finding that pyruvate mimicked the effects of glucose and impaired memory when combined with muscimol suggests that glucose metabolism may be involved in the memory-impairing interaction between glucose and GABA(A) receptors in the medial septum.     

内隐自尊的稳定性--成败操纵对内隐自尊的影响

本研究以瑞文智力测验为成败操纵基本任务,对成败操纵前后、接受成功反馈和失败反馈的个体在内隐联想测验中的反应及其内隐自尊情况进行了分析研究,结果表明：(1)不论是接受成功反馈还是失败反馈,成败操纵后,被试的反应速度都显著地快于操纵前;(2)不论是接受成功反馈还是失败反馈,成败操纵后,被试的内隐自尊水平都显著地低于操纵前。内隐自尊易受即时的关于自我的情绪体验的影响,具有不稳定性,当个体兴奋水平、情绪唤醒水平较高,动机较为强烈时,内隐自尊作用将受到抑制。