抗肿瘤药物心脏毒性的监测和治疗进展

许多临床常用的抗肿瘤药物均有不同程度的心脏毒性,常见的心血管并发症包括心力衰竭、心肌缺血、心律失常、高血压、低血压、血栓形成等。现就国内外近年对抗肿瘤药物心脏毒性的监测和治疗等方面的进展进行综述。     

Reading is believing: the truth effect and source credibility

Five experiments explored how source reliability influences people’s tendency to rate statements as more credible when they were encountered earlier (the truth effect). Undergraduates read statements from one reliable source and one unreliable source. Statements read multiple times were perceived as more valid and were more often correctly identified on a general knowledge test than statements read once or not at all. This occurred at varying retention intervals whether the statements originated from a reliable or unreliable source, when people had little memory for the statements themselves or their source, and when the discrediting information about the sources came either before or after reading the facts. While repetition aided recognition and source accuracy, both were unaffected by the reliability of the source. Consistent with the source monitoring framework, familiarity may create an illusion of truth for statements when people lack source-specifying cues, especially cues regarding the reliability of the source.     

Birth of the subject: the ethics of monitoring development programmes

NGO-based and rigorously monitored development programmes are bringing about important and positive socio-economic changes in the developing world. However, there are numerous instances of the employment of aggressive and grueling monitoring techniques which objectify the subject of development, the primary stakeholder, claiming development results as the successful achievement of goals of the donor or implementing organization. It is in this context that one can speak of an ethic of monitoring development programmes. The paper argues that such an ethic can be positively based on principles like empowering people through development work without hurting their sense of self-worth, the principle of trust and partnership and, negatively, never striving to objectify any person or people for the achievement of some objective, even if this objective is in itself honourable and desirable. The paper contends that if development is freeing the subject, the central player, to exercise their capability to live their life to the fullest, then development monitoring and development work in general has to enhance freedom, autonomy and openness.     

False recall in the Deese–Roediger–McDermott paradigm: The roles of gist and associative strength

Theories of false memories, particularly in the Deese–Roediger–McDermott (DRM) paradigm, focus on word association strength and gist. Backward associative strength (BAS) is a strong predictor of false recall in this paradigm. However, other than being defined as a measure of association between studied list words and falsely recalled nonpresented critical words, there is little understanding of this variable. In Experiment 1, we used a knowledge-type taxonomy to classify the semantic relations in DRM stimuli. These knowledge types predicted false-recall probability, as well as BAS itself, with the most important being situation features, synonyms, and taxonomic relations. In three subsequent experiments, we demonstrated that lists composed solely of situation features can elicit a gist and produce false memories, particularly when monitoring processes are made more difficult. Our results identify the semantic factors that underlie BAS and suggest how considering semantic relations leads to a better understanding of gist formation.