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171.
The physiological and expectancy effects of alcohol consumption on the aggressive behavior of 116 general-population males aged 18-45 years were analyzed separately in a naturalistic field experiment using a 3 × 3 Balanced Placebo Design (BPD). Participants were given a non-alcoholic drink, a drink targeting a Blood Alcohol Concentration (BAC) of .05%, or a drink targeting a BAC of .1%. Within these three groups, three expectancy levels were induced regarding the quantity of alcohol ingested. Aggressive behavior was measured as retaliation against an aggressive confederate, in the form of amounts of hot sauce and salt administered in a taste test. Expectancies significantly increased aggressive behavior, whereas actual quantity of alcohol ingested was unrelated to aggression. Aggressive dispositions also predicted aggressive behavior.  相似文献   
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173.
Ethanol is a frequently abused drug that impairs cognitive processes such as learning. Varenicline, an α4β2 nicotinic receptor partial agonist and α7 nicotinic receptor full agonist prescribed for smoking cessation, has been shown to decrease ethanol consumption. The current study investigated whether varenicline could ameliorate ethanol-induced deficits in learning and whether varenicline alters blood alcohol concentration in C57BL/6 mice. Conditioning consisted of two auditory conditioned stimulus (CS; 30 s, 85 dB white noise)—foot shock unconditioned stimulus (US; 2 s, 0.57 mA) pairings. For all studies, saline or ethanol (1.0, 1.5, 2.0 g/kg i.p.) was administered 15 min before training, and saline or varenicline (0.05, 0.1, 0.2 mg/kg i.p.) was administered 60 min before either training or testing. For blood alcohol analysis, saline or varenicline (0.1 mg/kg) was administered 60 min before collection, and saline or ethanol (1.0, 1.5, 2.0 g/kg) was administered 15 min before collection. Varenicline dose-dependently ameliorated ethanol-induced conditioning deficits for all three doses of ethanol when administered before training but not when administered 24 h later, before testing. In addition, varenicline did not alter blood alcohol concentration. The smoking cessation aid varenicline may have therapeutic uses for treating ethanol-associated disruptions in cognitive processes.  相似文献   
174.
    
Response expectancy is the anticipation of automatic, subjective, and behavioral responses to particular situational cues. More than a decade of research in diverse laboratories indicates that response expectancies are important considerations in designing and administering treatments and prevention programs for such problems as anxiety disorders, depression, substance abuse, and sexual dysfunction. Response expectancy also plays a central role in the effects of antidepressive medication, psychotherapy, and hypnosis. In addition, studies of the effects of placebos reveal that response expectancies can produce lasting changes in pain, anxiety, depression, alertness, tension, sexual arousal, alcohol craving and consumption, aggression, asthma, warts, and contact dermatitis. The veracity of many self-reported placebo effects have been corroborated by changes in physiological function.  相似文献   
175.
    
This paper is drawn from a narrative inquiry into how ex‐drug users understand the connection between childhood trauma and their subsequent drug misuse. The research was commissioned by a community drugs project. Eight participants were selected from respondents to an advertisement in a counselling journal, five of whom are qualified psychological therapists. The particular focus of this paper is on the interconnection of childhood trauma/abuse, drug misuse and parenting, by showing participants’ own experience of being parented and how the experience of becoming a parent helped them to transform their relationship with drugs. The paper draws attention to the therapeutic value of recognising the complex contextual factors that influence the parenting abilities of problematic drug users, and of building upon the positive attitudes, hopes, values and capabilities that underscore the ‘good parenting’ found in their stories. The work suggests that drug rehabilitation, treatment or counselling might usefully focus on parent–child relationships, which can become a turning point for identity transformation.  相似文献   
176.
    
It has been found that the Muslim population in the UK seek spiritual advice from traditional faith healers for psychiatric and related problems. The important role that religious beliefs may have on perceptions of mental illness and substance misuse warrants further investigation. The aims were to examine the views of Muslims faith healers on symptoms and changes in behaviour commonly described as “psychosis” and “substance misuse”. Eight semi-structured interviews were conducted with Muslim faith healers from various backgrounds. Data were analysed according to the conventions of qualitative research using grounded theory methods. Religious conceptualisations played a key role in the understanding of both the disorders and consequently the guidance given. There were similarities and differences in the narratives given for psychosis and substance misuse. Healers expressed doubt towards other faith healers and the methods utilised by scientific means. The findings suggest a need for close collaboration between faith healers and mental health workers in order to achieve a culturally sensitive health care system.  相似文献   
177.
    
The study assessed the prevalence of hazardous alcohol use among people living with HIV (PLHIV) and its correlates with socio-economic characteristics, disease variables and ART adherence in South Africa. The sample included 607 PLHIV (males =475, females =132; age range =18–61), sampled by all districts in the Eastern Cape. Participants were recruited through a health facility in the community through key informants or a support group. Results indicate that male PLHIV were more often than female PLHIV “past month” (18.9% vs. 6.1%) and hazardous alcohol drinkers (6.1% vs. 2.7%); using a cut-off score of 8 and more on the Alcohol Use Disorders Identification Test (AUDIT). Not having a disability grant for HIV/AIDS and the disability grant terminated were both related to past month alcohol use, while having the “disability grant stopped” was also related with hazardous or harmful drinking. Not having an AIDS diagnosis and not being on ART were both associated with past month alcohol use and hazardous or harmful drinking. CD4 counts and non-adherence to ART were both not significantly related with alcohol use status. Brief health provider initiated alcohol interventions for PLHIV should be promoted, with emphasis on targeting men.  相似文献   
178.
    
This study examined the cost of substance use disorders treatment in a large healthcare organization. A survival analysis demonstrated that family therapy utilised the least number of sessions (M = 2.41) when treating substance use disorders followed by individual therapy (M = 3.38) and mixed therapy (M = 6.40). Family therapy was the least costly of the three types, at $124.55 per episode of care for a client, with individual therapy costing $170.22 and mixed therapy $319.55. The ratio of family therapists utilising family therapy was more than three to one compared to other licensed professionals. The percentages of clients coming back for more than one episode of care are fewest for family therapy (8.9%) followed by mixed therapy (9.5%) and individual therapy (12.0%).  相似文献   
179.
    
This study examines the impact of acute alcohol intoxication on visual scanning in cross-race face learning. The eye movements of a group of white British participants were recorded as they encoded a series of own-and different-race faces, under alcohol and placebo conditions. Intoxication reduced the rate and extent of visual scanning during face encoding, reorienting the focus of foveal attention away from the eyes and towards the nose. Differences in encoding eye movements also varied between own-and different-race face conditions as a function of alcohol. Fixations to both face types were less frequent and more lingering following intoxication, but in the placebo condition this was only the case for different-race faces. While reducing visual scanning, however, alcohol had no adverse effect on memory, only encoding restrictions associated with sober different-race face processing led to poorer recognition. These results support perceptual expertise accounts of own-race face processing, but suggest the adverse effects of alcohol on face learning published previously are not caused by foveal encoding restrictions. The implications of these findings for alcohol myopia theory are discussed.  相似文献   
180.
    
The development of attention and executive functions in normal children (7–12 years) was investigated using a novel selective reaching task, which involved reaching as rapidly as possible towards a target, while at times having to ignore a distractor. The information processing paradigm allowed the measurement of various distinct dimensions of behaviour within a single task. The largest improvements in vigilance, set-shifting, response inhibition, selective attention, and impulsive responding were observed to occur between the ages of 8 and 10, with a plateau in performance between 10 and 12 years of age. These findings, consistent with a step-wise model of development, coincide with the observed developmental spurt in frontal brain functions between 7 and 10 years of age, and indicate that attention and executive functions develop in parallel. This task appears to be a useful research tool in the assessment of attention and executive functions, within a single task. Thus it may have a role in determining which cognitive functions are most affected in different childhood disorders.  相似文献   
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