联合常规细胞遗传学技术、多重巢式聚合酶链反应技术检测120例急性白血病患者遗传学异常

探讨如何提高急性白血病患者染色体／特异融合基因异常的检出率与准确率。联合常规细胞遗传学技术、多重巢式聚合酶链反应技术对120例急性白血病患者进行检测。结果表明：应用常规细胞遗传学检测出82例核型异常,占68．3％,而应用多重巢式聚合酶链反应技术检测出54例融合基因异常,占45％。联合这两种技术,120例急性白血病患者的遗传学异常检出率为：75％（90／120）,其中有65例明确了具体染色体改变或特异性融合基因异常。30例患者经常规细胞遗传学检测出具有t（8;21）（q22;q22）或t（15;17）（q22;q12）,多重巢式聚合酶链反应技术检测出39例患者具有AML1／ETO、PML／RARA或CBFB／MYH11融合基因异常。当存在染色体数目异常,或者不存在19种融合基因之一时多重巢式聚合酶链反应结果为阴性。提示常规细胞遗传学技术联合多重巢式聚合酶链反应技术可以有效地提高急性白血病患者染色体异常／特异性融合基因的检出率。     

Psychological contracts and their implications for commitment: A feature-based approach

Two studies were conducted to examine the link between employee perceptions of the psychological contract and their affective and normative commitments to the organization. The authors adapt a new approach to the study of psychological contracts by developing a generalizable measure of contract features (e.g., scope; time frame). In Study 1 (N = 301), the authors predicted and found that employees’ perceptions of the contract’s features contributed beyond perceptions of contract type (i.e., transactional; relational) and fulfillment to the prediction of affective and normative commitment. In Study 2 (N = 147), the features measure was refined and results from the first study were largely replicated. In both studies, affective and normative commitment were greater when employees viewed the contract as broad, trust-based, equal, negotiated, tangible, and long-term, and weaker when they saw it as unequal, imposed, and short-term. We also found evidence for patterns of features that correspond to transactional and relational contracts, as well as to recently proposed balanced contracts and I-Deals. Implications for theory and the management of psychological contracts are discussed.     

Reduction of appeasement‐related affect as a concomitant of diazepam‐induced aggression: evidence for a link between aggression and the expression of self‐conscious emotions

Aggressive responding following benzodiazepine ingestion has been recorded in both experimental and client populations, however, the mechanism responsible for this outcome is unclear. The goal of this study was to identify an affective concomitant linked to diazepam‐induced aggression that might be responsible for this relationship. Thirty males (15 diazepam and 15 placebo) participated in the Taylor Aggression Paradigm while covertly being videotaped. The videotapes were analyzed using the Facial Action Coding System with the goal of identifying facial expression differences between the two groups. Relative to placebo participants, diazepam participants selected significantly higher shock settings for their opponents, consistent with past findings using this paradigm. Diazepam participants also engaged in significantly fewer appeasement expressions (associated with the self‐conscious emotions) during the task, although there were no group differences for other emotion expressions or for movements in general. Aggr. Behav. 35:203–212, 2009. © 2008 Wiley‐Liss, Inc.     

How individualism–collectivism orientations predict happiness in a collectivistic context

We discuss how individualistic/collectivistic orientations of employees predict affective well-being at work, and how this relationship is moderated by the perceptions of spirit of camaraderie in organizations. The sample comprises 161 employees of 109 organizations operating in Portugal, a collectivistic culture. The findings suggest that: (a) collectivistic individuals show higher affective well-being than individualists; (b) this relationship is moderated by the employees’ perceptions of the spirit of camaraderie in their organizations; (c) higher affective well being levels tend to be experienced by collectivists who find working in an organizational context to be rich in spirit of camaraderie, and lower levels of affective well being are expressed by individualists who perceive poor spirit of camaraderie in their working environments. The paper emphasizes that employee happiness can have different bases in different cultures and that individualism/collectivism orientations do not operate in the same way in different cultural and organizational contexts. We are very grateful to the three anonymous reviewers for their helpful comments and suggestions.     

体验活动对冲动性购买行为的影响:情感反应视角

冲动性购买在商场和超市的零售中占有相当的比例,本研究以旅游者和旅游购物为实证研究对象,在323份调查问卷的基础上,采用方差分析和回归分析的方法探讨了体验活动对冲动性购买行为的影响及其情感反应机制。结果表明：在激发消费者冲动性购买行为方面,顾客参与的效果最好,其次是顾客学习,再次是顾客娱乐;顾客参与会导致更多的快乐的情感反应,而快乐的情感反应对冲动性购买意愿的影响最为显著;顾客学习会导致更多的支配的情感反应,而支配的情感反应对冲动性购买意愿的影响较为显著。     

数量化维度特征搜索的影响因素探索

有关数量化维度特征搜索的研究表明 ,目标搜索斜率 (反应时间对呈现项目数量函数的斜率 )是由目标与干扰子之间的差异决定的 ,然而以往研究中其差异的值取决于具体的实验条件。根据韦伯定律 ,笔者推测 ,目标搜索斜率应由目标与干扰子之间的相对差异 (C)决定 ,C为目标值 (T)与干扰子值 (D)的差值与该干扰子值的比值。当C值对应相等时 ,不同几何形状刺激的目标搜索斜率应无差异。为此笔者分别采用圆 (实验一 )和三角形 (实验二 )进行实验研究。实验结果支持了上述假设 ,并发现目标大于干扰子时的目标搜索斜率对C值的函数是单调递减函数     

Implicit learning revealed by the method of opposition

Complex information, such as that required for motor skills, can be learned implicitly, without awareness. Much debate has centered on the appropriate methods for proving that implicit learning is not influenced by explicit awareness. A recent study by Destrebecqz and Cleeremans has provided compelling evidence for implicit sequence learning without awareness by using the ‘method of opposition’.     

整合模型还是占优启发式模型? 从齐当别模型视角进行的检验

实验从齐当别模型的视角,通过对决策过程反应时的考察分别对以累积预期理论(cumulative prospect theory)为代表的整合模型和启发式模型家族的重要成员--占优启发式模型(priority heuristic)--进行检验。结果表明,决策过程反应时并未随着占优启发式模型所假定的决策步骤的增加而变慢;也未随着选项之间整体值差值的变大而变快;模糊决策过程的反应时反而快于风险决策过程的反应时。无论是以累积预期理论为代表的整合模型还是占优启发式模型均不能满意地描述和解释人们的实际决策过程,而齐当别模型则能解释大部分实验结果。文章建议多角度、多指标探讨人们的决策过程,检验、修改、完善,以及建立新的启发式模型或决策过程模型(process model),以增进对人们如何进行风险决策的理解。     

Bodies out of place: Affective encounters with whiteness

This essay foregrounds the role of affect in felt experiences of whiteness by illustrating two accounts, one that took place on 25th May 2020 between Amy Cooper and Christian Cooper in Central Park, and an encounter from the authors previous study on Black educators’ experiences of working in white spaces. In doing so, this essay is an affective attunement to the ways that felt intensities inform our experience of power relations and ultimately constrain the capacities of bodies to act.     

Empathy framework for embodied conversational agents

Empathy is a complex socio-emotional behavior that results from the interaction between affective and cognitive mechanisms. Equipping embodied conversational agents (ECAs) with empathic capacity can benefit from the integration and evaluation of these low and high level capabilities in a hierarchical manner. Following the theoretical background on empathic behavior in humans, this paper presents a framework to equip ECAs with real time multi-modal empathic interaction capabilities. We present the implementation of this framework, which includes basic dialogue capabilities as well as three levels of empathic behavior in a conversational scenario. Our approach is an inclusive stand on modeling levels of empathy and provides a baseline behavior for empathic interaction.