如何克服边界条件：来自记忆强度影响记忆去稳定的分子机制的启示

长时记忆在激活后首先会变得不稳定(去稳定过程), 继而会经历一个再巩固过程重新稳定下来以维持记忆的关联性。在再巩固期间给予电击、药理或行为训练以干预记忆再巩固, 可以更改原有记忆的强度或内容。这有望成为临床上治疗病理性记忆的一种方法。然而, 一些边界条件(记忆痕迹强、时间久远等)导致记忆在简单激活后不能去稳定, 不会经历再巩固过程, 使干预再巩固的方法无法发挥作用。动物实验表明, 通过药理学地调控参与记忆去稳定的分子的活动以促进记忆去稳定, 可以成功克服边界条件。可见, 边界条件不是绝对的。未来研究可进一步探索更多、更优的促进记忆去稳定并克服边界条件的方法, 提升干预记忆再巩固疗法的临床应用潜能。     

Pragmatic Inconsistency and Credibility

A critic may attack an arguer personally by pointing out that the arguer’s position is pragmatically inconsistent: the arguer does not practice what he preaches. A number of authors hold that such attacks can be part of a good argumentative discussion. However, there is a difficulty in accepting this kind of contribution as potentially legitimate, for the reason that there is nothing wrong for a protagonist to have an inconsistent position, in the sense of committing himself to mutually inconsistent propositions. If so, any such charge seems to be irrelevant. The questions to be answered in this essay are: what, if any, is the dialectical rationale for this type of criticism, and in what situations, if any, is this kind of charge dialectically legitimate? It will be shown that these attacks can be dialectically legitimate, in special circumstances, and that they can be seen as strategic?manoeuvres where a party attempts to reconcile his dialectical and his rhetorical objectives.     

Test of a social cognitive model of work satisfaction in teachers

Lent and Brown [Lent, R. W., & Brown, S. D. (2006). Integrating person and situation perspectives on work satisfaction: A social-cognitive view. Journal of Vocational Behavior,69, 236-247] recently proposed an integrative model of work satisfaction linked to social cognitive career theory. The model posits that work satisfaction is predicted by five classes of variables: work conditions, goal progress, self-efficacy, goal and efficacy relevant supports, and personality traits (e.g., positive affect). We tested this model in a sample of 366 teachers, finding good overall model-data fit. Of the five predictor classes, work conditions, self-efficacy, and positive affect were each found to explain unique predictive variance. This suggests that teachers who are most satisfied with their jobs see their work environment as supportive, are confident in their abilities to complete work-related tasks and goals, and report high levels of trait positive affect. Findings also offered support for the contention that measures of subjective person-environment fit may not be empirically distinct from work satisfaction. Implications of these findings for future research and applied efforts are considered.     

The partnership between the Early Intervention Institute,St Petersburg,and the Anna Freud Centre,London

The authors describe study and teaching links between the Early Intervention Institute in St Petersburg and the Anna Freud Clinic in London. Some brief clinical examples from a variety of settings are given as well as a longer case presentation. The impact of widespread institutional care, alcoholism and terrible housing conditions on child mental health are illustrated. This raises questions about the role of child psychotherapy when social conditions are so harsh. The case material indicates that, despite this, children can be helped in some measure to feel more secure, by the therapist providing constancy and reliability within an often frightening and dangerous external world.     

The relationship between sleep and working memory in children with neurological conditions

The objective of this study is to investigate whether sleep problems might account for the increased working memory deficits observed in school-aged children with neurological conditions. A novel, transdiagnostic approach to the investigation was chosen, and sleep is treated as a process that can potentially account for working memory difficulties across a range of neurological conditions. Prevalence estimates of sleep problems are also examined. Archival data of 237 children aged 6 to 11 years were collected from a Western Australian statewide neuropsychological service for the period 26 July 2011 to 14 January 2014. Measures of parent-reported sleep quality, snoring, and daytime sleepiness were obtained, in addition to objective measures of verbal and spatial working memory, storage capacity, and processing speed. The results of the data analysis reveal that over one third of participants reported having clinically-significant levels of sleep problems and that poor sleep quality is significantly associated with verbal working memory difficulties. This association remains after partialling out the variance contributed to performance by storage capacity and processing speed, suggesting that sleep is impacting upon an executive component of working memory. No other significant associations are observed. The results suggest that poor sleep quality is associated with an executive component of verbal (rather than spatial) working memory in children with neurological conditions. This has implications for the biological mechanisms thought to underlie the relationship between sleep and cognition in children. The results also demonstrate the clinical utility of a transdiagnostic approach when investigating sleep and cognition in children with neurological conditions.     

Determining Activity of the Autonomic Nervous System from Measurements of Autonomic Change

Three hundred and fifty female high school students observed an outcome of a hypothetical interpersonal dyadic interaction. The outcome was either a suicide (serious outcome) or a half-hearted suicide attempt (less serious outcome). In one condition, one of the actors was presented as intentionally performing certain actions which he or she knew could cause the other actor to attempt or actually commit suicide. In the other condition, the perpetrator acted in an unintentional manner. Ss' identifications with either the victim or the perpetrator were also manipulated. Furthermore, Ss were independently classified as to whether they considered circumstances (C) or intentionality (I) as the important factor in attributing responsibility. C-attributers identifying with the victim assigned more responsibility to the perpetrator for the serious outcome. C-attributers identifying with the perpetrator assigned more responsibility to that perpetrator in the less serious condition. Predictions for I-attributers were also confirmed.     

Thurstonian-Based Analyses: Past, Present, and Future Utilities

Current psychometric models of choice behavior are strongly influenced by Thurstone’s (1927, 1931) experimental and statistical work on measuring and scaling preferences. Aided by advances in computational techniques, choice models can now accommodate a wide range of different data types and sources of preference variability among respondents induced by such diverse factors as person-specific choice sets or different functional forms for the underlying utility representations. At the same time, these models are increasingly challenged by behavioral work demonstrating the prevalence of choice behavior that is not consistent with the underlying assumptions of these models. I discuss new modeling avenues that can account for such seemingly inconsistent choice behavior and conclude by emphasizing the interdisciplinary frontiers in the study of choice behavior and the resulting challenges for psychometricians. The author would like to thank R. Darrell Bock whose work inspired many of the ideas presented here. The paper benefitted from helpful comments by Albert Maydeu-Olivares and Rung-Ching Tsai. The reported research was supported in parts by the Social Sciences and Humanities Research Council of Canada.     

A new vision of a classical question: How to become a mother?

Abstract

This article offers a reflection on conception, pregnancy, and the first mother–infant relationships of mothers with motoric and sensory disabilities. Based on more than 13 years of experience with women with motoric and sensory disabilities who had a desire for a child, the author analyzes this unusual situation from three different points of view: the medical help to procreate, meeting a partner for the mother, and the link with the initial maternal family, i.e. the mother’s mother. The last part concerns the possibility of the development of a mother–infant relationship when bodily function is lacking.