对人类不良记忆的修饰：来自记忆再巩固的证据

已经巩固的长时记忆被再次提取后, 进入一个记忆的不稳定期, 在此过程中, 记忆可被更新、强化、削弱甚至抹除, 这个过程称为再巩固。人类不良记忆再巩固研究揭示记忆激活后口服普萘洛尔(propranolol)或进行消退训练可削弱或抹除不良情绪记忆, 此过程中涉及杏仁核、海马、前额叶皮层等脑区的参与及其构成的神经环路的调控。当前临床上利用再巩固原理可通过药物治疗、行为干预或无创脑部刺激的方法改变不良记忆。然而, 由于其形成过程复杂并受多种因素影响, 未来研究应尽可能模拟临床中人类不良记忆形成的复杂环境, 深入探讨再巩固“边界问题”, 推动实验室研究向临床应用的转化。     

Are economic conditions related to nonnormative life satisfaction development? Evaluating the relative impact of economic conditions,personality, and subjective health

This study examined the relative contribution of psychological and socioeconomic resources to explaining qualitative individual differences in life satisfaction development. We used growth mixture modeling and a cohort‐sequential design to investigate life satisfaction development from ages 25 to 65, in a nationally representative panel (the Socioeconomic Panel). Eighty‐three percent of the participants experienced stability in life satisfaction. In a subgroup of individuals (10%), life satisfaction declined. This subgroup lived under less favorable economic conditions and reported downward moves on an index of socioeconomic status. In another subgroup (7%), life satisfaction was low at age 25 and increased up to age 65. This group was also socioeconomically disadvantaged but scored higher on adaptive personality traits and experienced upward social mobility. Generally, personality traits explained level differences in life satisfaction better than economic conditions. However, economic conditions explained nonnormative life satisfaction development better than generalized control beliefs and the Big Five traits.     

Living Conditions and Psychological Distress in Latino Migrant Day Laborers: The Role of Cultural and Community Protective Factors

The purpose of this study was to examine the relationship between typically difficult living conditions and psychological distress in Latino migrant day laborers (LMDLs), with attention to the potentially protective roles of contact with family in country of origin (i.e., communication, sending money, etc.), availability of local culture (i.e., food, music, people from one's country of origin), and utilization of community resources perceived to be culturally competent (i.e., services that are respectful, able to serve Latinos, able to solve problems, in Spanish, etc.). Participants were 344 LMDLs surveyed in the San Francisco Bay Area. As hypothesized: (a) difficult living conditions were related to depression, anxiety, and desesperación [desperation], the latter a popular Latino idiom of psychological distress recently validated on LMDLs; (b) contact with family moderated the relation between difficult living conditions and depression and desesperación but not anxiety and (c) access to local culture, and utilization of community resources, mediated the relation between difficult living conditions and depression and desesperación but not anxiety. Implications for intervening at local and larger levels in order to provide some protection against distress built into the LMDL experience in the United States are discussed.     

Relevance differently affects the truth,acceptability, and probability evaluations of “and”, “but”, “therefore”, and “if–then”

In this study, we investigate the influence of reason-relation readings of indicative conditionals and “and”/“but”/“therefore” sentences on various cognitive assessments. According to the Frege–Grice tradition, a dissociation is expected. Specifically, differences in the reason-relation reading of these sentences should affect participants’ evaluations of their acceptability but not of their truth value. In two experiments we tested this assumption by introducing a relevance manipulation into the truth-table task as well as in other tasks assessing the participants’ acceptability and probability evaluations. Across the two experiments, a strong dissociation was found. The reason-relation reading of all four sentences strongly affected their probability and acceptability evaluations, but hardly affected their respective truth evaluations. Implications of this result for recent work on indicative conditionals are discussed.     

A concise derivation of the contact conditions at a migrating sharp interface

A sharp interface model can be used to simulate the kinetics of diffusional phase transformations provided the transformation process is controlled by migration of the interface and by diffusion of components in the bulk phases only. The contact conditions at the migrating sharp interface can be derived by applying the principles of mass balance and maximum dissipation. A concise derivation of the contact conditions on this basis is presented in this work.     

Systematic studies of modified vocalization: speech production changes during a variation of metronomic speech in persons who do and do not stutter

The most common way to induce fluency using rhythm requires persons who stutter to speak one syllable or one word to each beat of a metronome, but stuttering can also be eliminated when the stimulus is of a particular duration (e.g., 1 second [s]). The present study examined stuttering frequency, speech production changes, and speech naturalness during rhythmic speech that alternated 1 s of reading with 1 s of silence. A repeated-measures design was used to compare data obtained during a control reading condition and during rhythmic reading in 10 persons who stutter (PWS) and 10 normally fluent controls. Ratings for speech naturalness were also gathered from naïve listeners. Results showed that mean vowel duration increased significantly, and the percentage of short phonated intervals decreased significantly, for both groups from the control to the experimental condition. Mean phonated interval length increased significantly for the fluent controls. Mean speech naturalness ratings during the experimental condition were approximately “7” on a 1–9 scale (1 = highly natural; 9 = highly unnatural), and these ratings were significantly correlated with vowel duration and phonated intervals for PWS. The findings indicate that PWS may be altering vocal fold vibration duration to obtain fluency during this rhythmic speech style, and that vocal fold vibration duration may have an impact on speech naturalness during rhythmic speech. Future investigations should examine speech production changes and speech naturalness during variations of this rhythmic condition.Educational objectives: The reader will be able to: (1) describe changes (from a control reading condition) in speech production variables when alternating between 1 s of reading and 1 s of silence, (2) describe which rhythmic conditions have been found to sound and feel the most natural, (3) describe methodological issues for studies about alterations in speech production variables during fluency-inducing conditions, and (4) describe which fluency-inducing conditions have been shown to involve a reduction in short phonated intervals.     

Univariate repeated measures techniques applied to multivariate data

Repeated measures designs in psychology have traditionally been analyzed by the univariate mixed model approach, in which the repeated measures effect is tested against an error term based on the subject by treatment interaction. This paper considers the extension of this analysis to designs in which the individual repeated measures are multivariate. Sufficient conditions for a valid multivariate mixed model analysis are given, and a test is described to determine whether or not given data satisfy these conditions.     

System and flexibility in law

Usually, rhetoric is supposed to provide a model of law which describes legal interactions as volitive, arbitrary, and void of any system. However, the Mainz School, founded by Theodor Viehweg, proves the contrary: without referring to any metaphysics, such as consensus or auditoire universel, it seeks to discover the systematic character and the more or less flexible structures of legal rhetoric.