情绪对认知加工的影响：事件相关脑电位系列研究

为探讨情绪与认知的相互作用关系及其脑机制,建立了情境图片、面孔、汉字和声音四个系列组成的中国情感刺激材料库,并通过ERP实验对情绪与注意、工作记忆的关系以及特质焦虑者的认知特点进行了研究。结果发现：⑴ 负性情绪刺激在信息加工过程中至少在注意、评价及反应准备这几个阶段具有某种优先权,注意偏向也可在内隐任务下发生,负性刺激对注意资源不足具有某种补偿作用;⑵ 威胁性视觉提示对其后的视觉加工具有调节作用,高焦虑个体对这类性刺激投入了更多的视觉加工资源,而且威胁性刺激对注意的影响可以跨通道进行,威胁性的视觉刺激可以影响触觉注意;⑶ 在情绪对工作记忆的影响方面,负性情绪下空间工作记忆任务引起的P300波幅减小,这种效应可能是基于情绪对顶叶注意系统的调节作用,而在词语工作记忆任务中这种效应消失     

音乐绝对音高信息加工的脑机制

音乐绝对音高(absolute pitch, AP)一直是音乐心理学者感兴趣的问题。AP能力是一种特殊的音乐能力。ERP研究表明具有AP能力的群体只需较少的认知资源进行音高加工, 同时不同AP能力的加工机制也不同; 功能神经成像研究表明大脑左侧额叶背侧后部和左侧颞叶平面对AP加工发挥重要作用; 脑结构研究发现AP群体的某些脑区皮层厚度低于没有绝对音高能力(Non-AP)群体, 这可能与AP特殊的加工机制有关。AP能力形成需要先天遗传和后天环境的共同作用, 其相互作用的脑机制需结合行为遗传学的研究方法及成果。     

创造发明中顿悟的原型启发脑机制

科学界关于“原型启发”催化创造发明中顿悟发生的事例十分普遍, 从中国的“鲁班从带齿边的茅草中得到启发而发明锯子”的传说, 到“瓦特从沸腾的开水壶上受到启发而发明蒸汽机”的经典故事, 都说明“原型启发”是创造发明的一种重要思维方式。然而, 由于创造发明思维过程的复杂性, 国内外关于创造性思维脑机制的研究还停留在非科学问题解决的研究上。依据科学家运用原型启发而成功发明创造的最新实例, 项目组编制了《创造发明实验问题材料库》, 并计划以功能性磁共振成像(fMRI)和事件相关电位(ERP)作为技术手段系统探讨原型启发催化创造发明中顿悟发生的脑机制, 例如, 原型激活和启发信息利用的脑机制、问题意识下灵感捕捉的脑机制以及原型知识表征、动机与情绪状态、大脑工作状态等因素对原型启发影响的脑机制。该研究的开展, 对理解人类的创造性本质具有重要的理论意义, 对培养和激发人的创造力具有一定的实践价值。     

心理神经免疫学的研究及其思路问题

回顾并分析了心理神经免疫学的研究历史和发展,指出要深入揭示行为、精神活动是如何转化为影响健康的生理状态的奥秘,需要新的研究思路并讨论了新的研究路线     

Intimate Partner Violence (IPV) and Neurological Outcomes: A Review for Practitioners

ABSTRACT

Thirty-eight million women will experience intimate partner violence (IPV) during the course of their lifetime. Many of these women will experience brain injuries as a result of IPV and may not seek medical attention. Several types of practitioners who work with IPV survivors consistently, e.g., first responders, advocates, and clinicians, may be unfamiliar with brain functioning, screening, assessment, and treatment. This article reviews the dual traumas of IPV and TBI, the impact on neurological processes and symptomatology, and short and long-term outcomes. Recommendations for screening, intervention, interprofessional collaboration, and research are outlined.     

基因-脑-行为视角下的自伤行为产生机制

自伤是遗传与环境共同作用的结果。目前对于自伤行为的探讨已深入到基因及神经系统层面，基因-脑-行为的综合视角为客观揭示自伤产生机制提供了一条有效途径。本文将在已有研究的基础上，结合分子遗传学和神经生物学的最新成果，对自伤候选基因多态性及其可能的脑机制进行系统阐述，并提出今后应在基因多态性的交互作用及其脑机制、积极环境下自伤行为研究、自伤青少年的追踪研究以及自伤行为的系统性探讨等方面进一步深化。     

Mind matters: A narrative review on affective state-dependency in non-invasive brain stimulation

Variability in findings related to non-invasive brain stimulation (NIBS) have increasingly been described as a result of differences in neurophysiological state. Additionally, there is some evidence suggesting that individual differences in psychological states may correlate with the magnitude and directionality of effects of NIBS on the neural and behavioural level. In this narrative review, it is proposed that the assessment of baseline affective states can quantify non-reductive properties which are not readily accessible to neuroscientific methods. Particularly, affective-related states are theorized to correlate with physiological, behavioural and phenomenological effects of NIBS. While further systematic research is needed, baseline psychological states are suggested to provide a complementary cost-effective source of information for understanding variability in NIBS outcomes. Implementing measures of psychological state may potentially contribute to increasing the sensitivity and specificity of results in experimental and clinical NIBS studies.     

Depression and cognitive sequelae registered within the first year among young Danish TBI survivors

The aim of the study was to determine the proportion of depression and cognitive sequelae among young (15-30 years) Danish TBI survivors referred to interdisciplinary evaluation through a nationwide government-initiated health initiative. The cross-sectional study is based on data from the “Danish register for young adults with acquired brain injury” on TBI survivors included from October 2013 to December 2016. The main measures were Major depression inventory, Trail making test A and B, Fluency, Word learning with selective reminding, Matrix reasoning, Coding and Glasgow outcome scale - extended (GOS-E). During the study period, 131 young TBI survivors were referred to one of five national outpatient clinics. Ninety-six had complete data and of these 14.6% fulfilled the ICD-10 diagnostic criteria for depression and 34.4% had cognitive sequelae. An association was found between depression and cognitive sequelae (p = 0.004). Patients with both depression and cognitive sequelae (n = 10) had a significantly lower mean score on GOS-E (p = 0.0001). Depression and cognitive sequelae were frequent and associated with a poorer global functional outcome among young TBI survivors referred within a year after trauma. This finding and the notion that only 20% of the expected TBI population was referred to this nationwide health initiative indicate an unacknowledged need for interdisciplinary follow-up.     

Traumatic brain injury and adverse psychological effects: Examining a potential pathway to aggressive offending

Contemporary scholarship has demonstrated an association between traumatic brain injury (TBI) during adolescence and aggressive offending. Research, however, has yet to identify any mechanisms linking TBI to subsequent aggressive offending. Consequently, the current study hypothesized that adverse psychological effects is one such pathway. The current study used the Pathways to Desistance data set (n = 416) to examine the pathway of TBI to aggressive offending through adverse psychological effects. The findings of the structural equation model supported the hypothesized association. Specifically, increased exposure to TBI was indirectly associated with aggressive offending through adverse psychological effects. An additional supplemental analysis illustrated that a direct link between TBI and aggressive offending did not exist for the analytical sample. The findings suggested that the neurological disruptions commonly associated with TBI could result in direct increases in negative psychological outcomes and indirect increases in subsequent negative behavioral outcomes.     

Positive post‐disaster images: A daydream machine?

This study explores the impact of post‐earthquake images inserted in a vigilance task, in terms of performance, self‐reports of task‐focus, and cerebral activity using functional near‐infrared spectroscopy (fNIRS). Vigilance tasks present a sequence of stimuli in which only a few are pre‐designated critical or target stimuli requiring an overt response from the participant. Seventy‐one residents participated (51 women, 20 men) by taking part in a vigilance task with task‐irrelevant images inserted in the sequence. There were three conditions consisting positive (emotive inducing), negative (emotive inducing), and control (devoid of meaning) images embedded in the vigilance task to assess possible impacts on vigilance performance. The images were obtained through crowdsourcing and represented parts of the city 3–4 years post‐earthquake. Task performance was assessed with signal detection theory metrics of sensitivity A’ and bias β’’. This enables the separation of an individual's ability to accurately discriminate critical signals from non‐critical stimuli (sensitivity) and shifts in their willingness to respond to any stimuli whether critical or not (bias). Individuals viewing the positive images, relating to progress, rebuild, or aesthetic aspects within the city, had a more conservative response bias (they responded less to both rare critical and distractor stimuli) than those in the other conditions. These individuals also reported lower task‐focus, as would be expected. However, contrary to expectations, indicators of cerebral activity (fNIRS) did not differ significantly between the experimental groups. These results, when combined, suggest that mind wandering events may be being generated when exposed to positive post‐earthquake images.