The Compassionate Treatment of Animals

The compassionate treatment of animals has been the focal point of speeches and writings by one of the most influential Buddhist cleric‐scholars on the Tibetan plateau today, Khenpo Tsultrim Lodrö of Larung Buddhist Academy. This essay surveys the Khenpo's broad‐based advocacy for animal welfare and details his discrete appeals to nomads in eastern Tibet to forgo selling livestock for slaughter, to eat a vegetarian diet on religious holidays, to relinquish wearing animal fur, to protect wildlife habitat, and to liberate the lives of animals. I focus on the modernist “this worldly” dimension of his advocacy, calling attention to how Tsultrim Lodrö goes beyond traditional scare tactics that emphasize the karmic effects of negative deeds in future lives and instead invokes compassion by attending to the lived experience and suffering of animals. In doing so, the Khenpo positions Buddhism as a civilizing force in order to reform certain Tibetan customs and mitigate the influence of Chinese modernity and state marketization policies. I argue that his strategy of “reverse orientalism” appropriates state civilizational discourse and reverses its terms.     

Current issues in theory construction: A commentary on Waters and Sroufe

The view of competence proposed by Waters and Sroufe remains faithful to a kind of theorizing about human personality which emphasizes its unitary and universal properties. Developments in other areas of inquiry, however, are redirecting theoretical efforts toward a more pluralistic and contextualistic view of human nature and development. Implications for future theories of development are discussed.     

Using targeted visceroception to improve interoceptive sensibility and emotion regulation

Focusing on one's body can improve the awareness and regulation of emotion. Interoception – sensing the physiological condition of the body, particularly of the viscera – appears to play an important role. While the majority of previous research studies have examined interoceptive sensitivity (i.e., detection of objectively measurable physiological changes), there has been relatively limited investigation of interoceptive sensibility (i.e., subjective awareness of those changes), and even fewer studies permitting causal conclusions. The current study is part of a randomised controlled trial on visceroception in the context of emotion regulation, using an 8-week intervention involving focused attention on either cardiac or gastrointestinal activity. Group differences in emotion regulation and reactivity were assessed using the Multidimensional Assessment of Interoceptive Awareness (MAIA), the Difficulties in Emotion Regulation Scale, and the Emotion Reactivity Scale (ERS). The findings suggest that focussed attention on gastrointestinal activity (i.e., gastroception), in particular, improves interoceptive sensibility and emotion regulation, as evidenced by increases on the MAIA's Noticing, Body Listening, and Self-regulation subscales, and decreases on the Arousal subscale of the ERS. Gastroception may make distinct contributions to the benefits of body focus in a research context where the gut is often overlooked.     

Stages-of-learning analysis of developmental interactions in memory,with illustrations from developmental interactions in picture-word effects

Although Age × Treatment interactions have been widely viewed as key results in theories of memory development, most examples of such results (e.g., Age × Treatment interactions in the effects of item concreteness, item elaboration, and organizational context) have been identified in list-learning experiments where children of different ages receive a small, fixed number of study-test cycles on the target list. A stages-of-learning analysis reveals that such designs confound a treatment's potential interactions with age and its potential interactions with stage of learning. The analysis also reveals specific situations in which such designs will produce converging, diverging, and crossover Age × Treatment interactions even though the treatment does not interact with age in any way. A series of experiments is reported in which a mathematical model that incorporates stages-of-learning distinctions is applied to the well-known interaction between age and item concreteness (pictures versus words) in cued recall. Although a diverging Age × Treatment interaction has been observed in previous research, it was found that there are at least four different interactions between the picture-word manipulation and age; (a) a diverging interaction at storage that operates throughout elementary school; (b) a diverging interaction localized within retrieval learning and operating during the first half of the elementary school; (c) a converging interaction localized within retrieval learning and operating during the second half of elementary school; and (d) a diverging interaction localized within retrieval performance and operating throughout elementary school.     

Towards modern post-coma care based on neuroscientific evidence

BackgroundUnderstanding the mechanisms underlying human consciousness is pivotal to improve the prognostication and treatment of severely brain-injured patients. Consciousness remains an elusive concept and the identification of its neural correlates is an active subject of research, however recent neuroscientific advances have allowed scientists to better characterize disorders of consciousness. These breakthroughs question the historical nomenclature and our current management of post-comatose patients.MethodThis review examines the contribution of consciousness neurosciences to the current clinical management of severe brain injury. It investigates the major impact of consciousness disorders on healthcare systems, the scientific frameworks employed to identify their neural correlates and how evidence-based data from neuroimaging research have reshaped the landscape of post-coma care in recent years.ResultsOur increased ability to detect behavioral and neurophysiological signatures of consciousness has led to significant changes in taxonomy and clinical practice. We advocate for a multimodal framework for the management of severely brain-injured patients based on precision medicine and evidence-based decisions, integrating epidemiology, health economics and neuroethics.ConclusionsMajor progress in brain imaging and clinical assessment have opened the door to a new era of post-coma care based on standardized neuroscientific evidence. We highlight its implications in clinical applications and call for improved collaborations between researchers and clinicians to better translate findings to the bedside.     

Impaired social learning in patients with major depressive disorder revealed by a reinforcement learning model

Background/objectivePatients with major depressive disorder (MDD) have altered learning rates for rewards and losses in non-social learning paradigms. However, it is not well understood whether the ability to learn from social interactions is altered in MDD patients. Using reinforcement learning during the repeated Trust Game (rTG), we investigated how MDD patients learn to trust newly-met partners in MDD patients.MethodSixty-eight MDD patients and fifty-four controls each played as ‘investor’ and interacted with ten different partners. We manipulated both the level of trustworthiness by varying the chance of reciprocity (10, 30, 50, 70 and 90%) and reputation disclosure, where partners’ reputation was either pre-disclosed or hidden.ResultsOur reinforcement learning model revealed that MDD patients had significantly higher learning rates for losses than the controls in both the reputation disclosure and non-disclosure condition. The difference was larger when reputation was not disclosed than disclosed. We observed no difference in learning rates for gains in either condition.ConclusionsOur findings highlight that abnormal learning for losses underlies the social learning process in MDD patients. This abnormality is higher when situational unpredictability is high versus low. Our findings provide novel insights into social rehabilitation of MDD.     

Sleep dependent consolidation of gross motor sequence learning with motor imagery

Acquisition of gross motor sequence learning with physical and mental training elicits gains in performance. However, the effects of sleep or daytime consolidation after both types of practice remain unclear, especially the effects upon the goal- and movement-based components of a gross motor sequential task. The main purpose of this study was to test the effect of physical practice (PP) and motor imagery practice (MIP) on the acquisition and consolidation processes of gross motor sequence learning.Seventy-six participants were tested before and after PP or MIP on a whole-body sequential paradigm, following either a night of sleep (PP_sleep and MIP_sleep groups) or an equivalent daytime period (PP_day and MIP_day groups). Control groups without training were tested following similar timespans (CTRL_sleep and CTRL_day groups). The number of sequential movements and the centre of mass displacement – corresponding to goal and movement-based components, respectively – were assessed.Results showed that relative to the CTRL groups, the PP and MIP groups improved performance during acquisition. Importantly, only the MIP_sleep group further improved performance after a night of sleep; participants of other groups stabilised their performance after consolidation. Additionally, the number of sequential movements and the centre of mass displacement evolved conjointly without being influenced by the type of training or the nature of the consolidation.To conclude, these results confirm that sleep contributes to the consolidation of gross motor sequence learning acquired with MIP but not PP. The relationship between the goal- and movement-based components of a gross motor sequential task is discussed.