Th17细胞在胸腺瘤合并MG发病机制中作用的探讨

探讨Th17细胞在胸腺瘤合并重症肌无力（MG）发病中的作用。分析27例胸腺瘤患者相关资料,免疫组化法确定瘤组织中IL-17和CD4^＋T细胞表达。结果为胸腺瘤合并MG男性年龄低于女性,瘤组织高表达IL-17和CD4^＋T细胞。B1和B2型易合并MG。结论是Th17细胞和IL-17在胸腺瘤合并MG发病中有一定作用。     

Resistance to yielding and the expectation of cooperative future interaction in negotiation

The expectation of cooperative future interaction (ECFI) encouraged especially high joint benefit (the total of the two bargainers' individual outcomes) when resistance to yielding was high, but especially low joint benefit when resistance to yielding was low. Process data suggest that this finding can be explained as follows: When resistance to yielding is high, ECFI encourages problem solving and reduced contentious behavior; when resistance to yielding is low, ECFI encourages a collapse of aspirations. The results support Filley's (1975) dualconcern model and cast doubt on Deutsch's (1973) blanket assertion that a cooperative process leads to constructive conflict resolution.     

A developmental perspective on reading dysfunction: Accuracy and rate criteria in the subtyping of dyslexic children

Children referred with specific reading dysfunction were subtyped as accuracy disabled or rate disabled according to criteria developed from an information processing model of reading skill. Multiple measures of oral and written language development were compared for two subtyped samples matched on age, sex, and IQ. The two samples were comparable in reading fluency, reading comprehension, word knowledge, and word retrieval functions. Accuracy disabled readers demonstrated inferior decoding and spelling skills. The accuracy disabled sample proved deficient in their understanding of oral language structure and in their ability to associate unfamiliar pseudowords and novel symbols in a task designed to simulate some of the learning involved in initial reading acquisition. It was suggested that these two samples of disabled readers may be best described with respect to their relative standing along a theoretical continuum of normal reading development.     

The effect of context during word perception in schizophrenic patients

Hospitalized chronic and acute schizophrenics were compared with age- and social-status-matched controls on word perception tests to measure the effect of context on recognition thresholds. In Experiment 1 the method of J. Morton (1964, British Journal of Psychology, 55, 165-180) was adopted to see how related and unrelated contexts influenced word recognition thresholds when both context and stimulus word were presented visually. Experiment 2 was an auditory analog of Experiment 1 and in addition the chronic schizophrenics were selected on the basis of a presence or absence of auditory hallucinations. The influence of context on perceptual thresholds was quite normal in all schizophrenics. However, analysis of the incorrect responses elicited showed that some schizophrenic subjects do produce bizarre or irrelevant responses or perseveration to a greater extent than their controls. These results are explained in terms of automatic and strategic modes of information processing. The automatic processes responsible for the adjustment of perceptual thresholds operate normally in schizophrenics but response production which demands strategic selection and editing of responses is prone to malfunction which results in the observed deviations in the normal use of language.     

Asymmetry of perception in free viewing of chimeric faces

We have devised a new free-vision task to index functional cerebral asymmetry for processing facial characteristics. Confirming its sensitivity to properties of lateralized hemispheric functions, left- and right-handers were clearly differentiated on this task with respect to several aspects of performance that conform with known differences between handedness groups in hemispheric asymmetry. Additionally, there were highly reliable and stable individual differences in perceptual asymmetries within handedness. Analyses of items in the task revealed that most of the differences between items in the asymmetries they elicited were random.     

Facing up to the issues: Reply to Hellige (1983)

In a recent article in this journal, Hellige (Brain and Cognition, 2, 199-203, 1983) presented a critique of the chimeric-face technique that was used by us to validate a hand preference questionnaire. Data were presented by Hellige to show that the left visual field (LVF) bias that occurs on this task is due primarily to differences in detail in the features of the two faces and not because of right hemisphere dominance for face perception. In our rebuttal, we acknowledge that the two faces are not mirror-image duplicates of each other, but contend that this fact does not explain why differences between left-handers and right-handers have been observed on this task. Further data on the role of handedness as well as other variables impacting on this task are presented. A possible explanation is also offered for the rather small extent of LVF bias that Hellige obtained when he used corrected (i.e., true mirror-image) versions of Jaynes' chimeric faces.     

Generalized and lateralized effects of concurrent verbal rehearsal upon performance of sequential movements of the fingers by the left and right hands.

College student subjects performed a sequential typing task requiring bilaterally synchronized movements (Experiment 1) or unilaterally synchronized movements (Experiment 2) singly, and concurrently with silent and vocal rehearsal of verbal lists varying in redundancy. Rehearsal interfered with bilaterally synchronized movements more when the right hand was leading the sequence than when the left hand led, and with movements of the right more than the left hand in unilaterally synchronized movements. Results are interpreted in terms of intrahemispheric and general capacity competition between the concurrent performances.     

Use of first person pronouns as a function of increased objective self-awareness and performance feedback

A recent integrating formalation in social psychology, the Duval-Wicklund theory of “objective self-awareness,” has the core assumption that attention focused on the self is always aversive and, hence, avoided. While faced with either a TV camera or a mirror, and after they had received false feedback concerning their creativity, 98 undergraduates guessed at the meaning of foreign language pronouns, the unobtrusive dependent measure of the direction of the focus of attention. The standard Duval-Wicklund effect was replicated—more attention to self, that is, more first-person pronouns—in the “camera” or “mirror” than in the “no camera” or “no mirror” conditions. However, within the camera or mirror conditions, avoidance of self-focused attention occurred only after negative feedback.     

Job satisfaction among students in work education programs

Data were collected from 1016 students in grades 9–14 from 50 work education programs. Data were also collected from 696 similar students who held part-time jobs but were not participating in work education programs. Participating students were significantly more satisfied with their jobs than were the nonparticipating students. Group atmosphere, availability of adult role models, meaningfulness of work roles, and availability of feedback accounted for much of the variation in job satisfaction among students.