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61.
为了探讨肝激酶B1(LKB1)蛋白在食管鳞癌组织中的表达水平及其与食管鳞癌临床特征及生存期的关系,应用免疫组化方法检测120例食管鳞癌患者组织中LKB1蛋白表达情况并对诸多临床特征进行相关性分析研究,发现LKB1蛋白在食管癌旁正常组织的阳性表达率高于癌组织;LKB1蛋白表达与患者年龄、性别、肿瘤部位、病变长度及浸润深度无关而与分化程度、淋巴结转移及临床分期(TNM)相关,且LKB1蛋白阴性组预后较阳性组差.可见LKB1视为抑癌基因影响食管鳞癌的预后,可能成为食管鳞癌新型的临床预后指标之一. 相似文献
62.
This paper addresses B. F. Skinner's utopian vision for enhancing social justice and human well-being in his 1948 novel, Walden Two. In the first part, we situate the book in its historical, intellectual, and social context of the utopian genre, address critiques of the book's premises and practices, and discuss the fate of intentional communities patterned on the book. The central point here is that Skinner's utopian vision was not any of Walden Two's practices, except one: the use of empirical methods to search for and discover practices that worked. In the second part, we describe practices in Skinner's book that advance social justice and human well-being under the themes of health, wealth, and wisdom, and then show how the subsequent literature in applied behavior analysis supports Skinner's prescience. Applied behavior analysis is a measure of the success of Skinner's utopian vision: to experiment. 相似文献
63.
干扰素治疗慢性乙型肝炎管理策略初探 总被引:4,自引:0,他引:4
在慢性乙肝抗病毒治疗中干扰素作为一线治疗取得了一定的疗效。在治疗过程中通过选择合适的慢性乙肝患者、监测疗效、确立个体化的疗程和剂量、及时监测不良反应和恰当的处理和最大限度的提高患者的依从性可使干扰素的疗效达到最大化。 相似文献
64.
Roger Baumann 《Journal for the scientific study of religion》2023,62(Z1):48-67
W.E.B. Du Bois was thoroughly ambivalent about the political significance of American Black churches regarding their role in challenging racial inequality. He saw them as integral to Black social life, but also as failing to live up to their potential as drivers of liberation. And, while he focused primarily on Black churches within the United States, Du Bois was also committed to Black liberation on a global level. This suggests great potential for applying DuBois’ analyses of Black religion to the question of transnational religious and racial solidarities and the global political salience of “the Black Church” as a category. In this context, this article explores the significance of DuBois’ work for analyzing the category of “the Black Church.” It does so through a comparative case study of African American Christian engagement with the issue of Israel and Palestine, with four case studies ranging from African American Christian Zionists to Palestinian solidarity activists. Across these cases, the analysis highlights the ways that the history, identity, and mission of “the Black Church” are invoked in the context of Palestine and Israel. It argues that “the Black Church” is best understood as a contested category of collective religious and racial identity. 相似文献
65.
Traffic safety has always been a hot topic for human-driven (HDV) and autonomous vehicles (AV) mixed flow. The conflict between permitted right-turn vehicles (PRT) and opposing through vehicles (TH) at signalized intersections (left-handed traffic) is extraordinarily critical. AVs with aggressive behaviors are able to accept short gap time without losing safety. However, such a turning maneuver may lead to dangerous feelings and cause unexpected reactions of approaching drivers. This study aims to investigate and model drivers’ reactions in TH movements to PRT AVs considering the trust degree of drivers to AVs. Questionnaire surveys and driving simulator experiments were conducted for 41 participants. Results reveal that the right turn timing of PRT AV will significantly influence drivers’ reactions. Basically, TH drivers will brake with a high probability under the situation of small expected post encroachment time (PET). It is also found that female drivers and drivers with low trust in AVs are more vigilant to PRT AVs than other drivers. Based on this finding a two-layer model for reproducing TH drivers’ reactions to PRT AVs is proposed. The first layer is to determine the braking decision and the second layer is to calculate the parameters of braking behaviors (brake lag, braking time, and speed drop). The significance and coefficients variables in these models proved that the trust in AV will influence drivers’ decisions and braking behaviors (brake lag and braking time). The more the drivers trust AVs, the smaller the expected PET to AVs they can accept for passing without braking, and the more gently they will brake (longer brake lag and shorter braking time) due to the cutting in of PRT AVs. This effect will become significant after drivers have experienced several interactions with AVs. 相似文献
66.
Sandra F. Fox 《Journal of Modern Jewish Studies》2018,17(2):156-172
The postwar period brought sweeping changes for American Jews. Communal socioeconomic transitions and the aftermath of the Holocaust triggered intense anxieties among Jewish leaders regarding the preservation of so-called Jewish “authenticity,” and to an increased focus on the moulding of American Jewish youth. This article considers how Jewish summer camps used Tisha B’Av and secular, alternative memorial days, to lead campers toward various, ideologically imbued visions of Jewish authenticity. Through fostering an aura of tragedy in what was otherwise a world of play, songs, and enjoyment, Jewish educators used memorial days as transformative educational tools. Though camps’ ceremonies looked remarkably similar, often including a carefully crafted sombre atmosphere, dirges, and responsive readings, the message of the days proved malleable to different ideological perspectives. This article considers how Zionist, Yiddishist, Reform and Conservative camps came to use memorial days to produce “real,” “ideal,” or “authentic” Jews in accordance with their ideological visions in the decades immediately following the Holocaust. 相似文献
67.
68.
The vasopressin V1b receptor (AVPR1B) gene has been shown to be closely associated with bipolar disorder and depression. However, whether it relates to positive social outcomes, such as empathy and prosocial behavior, remains unknown. This study explored the possible role of the AVPR1B gene rs28373064 in empathy and prosociality. A total of 256 men, who were genetically unrelated, non‐clinical ethnic Han Chinese college students, participated in the study. Prosociality was tested by measuring the prosocial tendencies of cognitive and emotional empathy using the Interpersonal Reactivity Index (IRI). The single nucleotide polymorphism (SNP), rs28373064, was genotyped using a polymerase chain reaction–restriction fragment length polymorphism (PCR‐RFLP) analysis. The results suggest that the AVPR1B gene rs28373064 is linked to emotional empathy and prosociality. The mediation analysis indicated that the effect of the AVPR1B gene on prosociality might be mediated by emotional empathy. This study demonstrated the link between the AVPR1B gene and prosociality and provided evidence that emotional empathy might mediate the relation between the AVPR1B gene and prosociality. 相似文献
69.
Maria Johansson Linda Forssman Gunilla Bohlin 《Scandinavian journal of psychology》2014,55(2):130-135
This study used the classical A‐not‐B task (Piaget, 1954 ) to explore individual differences in cognitive flexibility in 10‐month‐old infants by: (1) examining how differences in search performance during A trials relate to search performance during B trials; (2) studying the relation between temperamental dimensions and A‐not‐B performance; and (3) investigating differences in search performance between looking and reaching responses within the same task. Forty infants were tested on a fixed‐design‐version of the A‐not‐B task, not allowing for training or individual adjustment, but instead eliciting additional search behaviors than the common correct responses in A trials and perseverative errors in B trials. Infants were also rated by their parents on the temperamental scales Activity level and Attention span. The main findings were: (1) performance on A trials affected B trial performance, with infants being more correct on A trials having more incorrect and less ‘no search’ responses on B trials; (2) activity level, but not attention span, was related to performance on the A‐not‐B task, with infants performing better on A trials having a lower activity level; and (3) there were a few differences in performance with regard to modality, indicating that responding correctly by looking may be less cognitively demanding than doing so by reaching. This study demonstrated that 10‐month‐olds show a wide variation of search behaviors on this A‐not‐B task, resulting in individual differences in performance. These differences are suggested to reflect variation in temperamental activity level as well as maturity of short term/working memory, inhibition and cognitive flexibility. 相似文献
70.