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Trevor T.‐J. Chong Valerie Bonnelle Kai‐Riin Veromann Julius Juurmaa Pille Taba Olivia Plant Masud Husain 《Journal of Neuropsychology》2018,12(2):291-297
Methcathinone‐induced Parkinsonism is a recently described extrapyramidal syndrome characterized by globus pallidus and substantia nigra lesions, which provides a unique model of basal ganglia dysfunction. We assessed motivated behaviour in this condition using a novel cost‐benefit decision‐making task, in which participants decided whether it was worth investing effort for reward. Patients showed a dissociation between reward and effort sensitivity, such that pallidonigral complex dysfunction caused them to become less sensitive to rewards, while normal sensitivity to effort costs was maintained. 相似文献
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