Concurrent access to two concentrations of orally delivered phencyclidine: effects of feeding conditions.

Two experiments addressed the effects of food satiation and deprivation on oral self-administration of two concurrently available phencyclidine concentrations. In the first experiment, 8 rhesus monkeys self-administered either of two concentrations of phencyclidine ("PCP, angel dust") and water under concurrent fixed-ratio 16 schedules. One concentration was always held constant (0.25 mg/mL) while a series of other phencyclidine concentrations, ranging from 0 (water) to 1.0 mg/mL, was presented in a nonsystematic order. Initially the monkeys were tested while food satiated, and the procedure was then repeated during food deprivation. The monkeys usually selected the higher concentration within the first few minutes of the session, indicating that taste and/or other immediate postingestional effects were important factors. Contrary to a number of previous reports, there were no consistent differences across subjects in the mean number of liquid deliveries or mean drug intake (mg/kg) during food satiation and deprivation. However, for all monkeys the within-session time course of responding during food satiation consistently differed from that during deprivation. A second experiment assessed whether the failure to find consistent differences in drug intake during food satiation and deprivation had been due to the history of concurrent access to different phencyclidine concentrations or to the extended experience with phencyclidine under food-satiation conditions. Six additional monkeys (Group 2) were exposed to the phencyclidine self-administration procedure (during food satiation and deprivation) for the same length of time as the monkeys in Experiment 1 (Group 1), except they received only concurrent access to phencyclidine (0.25 mg/mL) and water. Both groups then received concurrent access to phencyclidine and water during five repeated cycles of food deprivation and satiation. There were also marked individual differences in Group 2: During food satiation, 2 of the monkeys' responding increased, 1 showed no change, and 3 decreased. Examination of a number of historical variables indicated that the greater the percentage of total sessions spent during food satiation with phencyclidine available (before these experiments began), the greater the amounts of phencyclidine consumed during food satiation and the smaller the differences in phencyclidine intake when the two feeding conditions were compared.     

Behavior regulation and learned performance: Some misapprehensions and disagreements

The behavior-regulation approach to learned performance has been the subject of misapprehension and disagreement concerning: (1) the nature and importance of behavior regulation, (2) the definition and role of behavioral set-points, (3) the relation of optimal schedule performance to behavioral set-points, and (4) the question of whether deviations from total responding or from response patterns are the primary determinant of molar responding under schedule constraint. After clarifying the nature and role of behavior regulation and set-points, this paper shows that the data used to question optimal schedule performance (Allison, 1981a) actually strongly support the general behavior-regulation approach. These data also indicate a role for response-pattern set-points in determining schedule behavior, but contradict the hypothesis that deviations from response-pattern characteristics are the primary determinant of molar schedule effects.     

Affection deprivation is more aversive than excessive affection: A test of affection exchange theory

Affection exchange theory predicts that both excessive affection and affection deprivation are associated with poorer health, compared with receiving the level of affectionate communication that one desires. A similar yet-untested prediction is that affection deprivation is more aversive than excessive affection. This preregistered study tested both hypotheses on a battery of mental and physical health outcomes, including depression, loneliness, stress, physical pain, frequency of nightmares, and sleep quality, using a Census-matched sample of U.S. American adults (N = 827). As hypothesized, receiving the right amount of affection was associated with more health-supportive scores on all outcomes than either excessive or deficient affection. Similarly, excessive affection was associated with lower depression, loneliness, stress, and pain, and higher sleep quality, than affection deprivation.     

Food-deprivation effects on punished schedule-induced drinking in rats.

Food-deprived rats (at 80% of their free-feeding weights) were exposed to a fixed-time 60-s schedule of food-pellet presentation and developed schedule-induced drinking. Lick-dependent signaled delays (10 s) to food presentation led to decreased drinking, which recovered when the signaled delays were discontinued. A major effect of this punishment contingency was to increase the proportion of interpellet intervals without any licks. The drinking of yoked control rats, which received food at the same times as those exposed to the signaled delay contingency (masters), was not consistently reduced. When food-deprivation level was changed to 90%, all master and yoked control rats showed decreases in punished or unpunished schedule-induced drinking. When the body weights were reduced to 70%, most master rats increased punished behavior to levels similar to those of unpunished drinking. This effect was not observed for yoked controls. Therefore, body-weight loss increased the resistance of schedule-induced drinking to reductions by punishment. Food-deprivation effects on punished schedule-induced drinking are similar to their effects on food-maintained lever pressing. This dependency of punishment on food-deprivation level supports the view that schedule-induced drinking can be modified by the same variables that affect operant behavior in general.     

The economics of daily consumption controlling food- and water-reinforced responding

In the first experiment, two rhesus monkeys earned their entire ration of food and water during daily sessions with no provisions to ensure constant daily intakes. Two variable-interval schedules of food presentations were concurrent with one variable-interval schedule of water presentations; the maximum rate of food presentations arranged by one food schedule was varied. As the rate of food presentations was increased, the absolute level of responding on the two food schedules combined decreased, while responding on the water schedule increased. The preference for the variable food schedule compared to the other food schedule approximately matched the proportion of reinforcers obtained from it. The preference for the variable food schedule compared to the water schedule did not match, but greatly decreased, as the proportion of reinforcers from the food schedule increased. When Experiment I was replicated, with provisions to ensure constant daily intakes of food and water (Experiment II), the absolute response rates under the two food schedules combined and under the water schedule no longer changed with increases in the rate of food during the sessions. On the other hand, choice between the two food schedules remained proportional to the distribution of obtained food pellets. These results were interpreted as indicating that behavior to obtain nonsubstitutable commodities, such as food and water, is strongly controlled by the economic conditions of daily consumption, while choice between substitutable commodities is independent of these factors.     

Beyond the relational principle of reinforcement

Behavior under baseline conditions in which the contingency is absent can shed some light on the individual's performance under a schedule, but is insufficient as a basis for prediction of performance. This insufficiency of the baseline data runs counter to a recent formalization of the relational principle of reinforcement (Donahoe, 1977). A more satisfactory predictive model must incorporate not only the baseline level of the instrumental response and that of the contingent response, but also the schedule requirements, the character of each response in relation to the other, and the behavior required in simply switching from each to the other.     

Effects of food deprivation and reinforcement magnitude on conditioned suppression

In Experiment I, the responding of rats lever pressing on a variable-interval schedule for sucrose solution was partially suppressed by a variable duration conditioned stimulus followed by shock. When food deprivation was increased, response rates during and before the conditioned stimulus increased monotonically. Varying the concentration of sucrose across blocks of sessions or from session to session in a semi-random sequence had little effect on response rates either before or during the conditioned stimulus. With a fixed sequence of increasing concentrations across a five-session block, increased concentration produced much more rapid increases in response rates before than during the conditioned stimulus. In Experiment II, rats were presented with the same sequence of increasing concentrations across a five-session block. When tested at 80% body weight, response rates increased rapidly as concentration increased, but at 100%, body-weight rates increased only slightly. The effect of a change in body weight in Experiment II thus mimicked the effect of the conditioned stimulus in the latter part of Experiment I. These findings support the view that the effect of a pre-aversive conditioned stimulus is similar to that of a change in food deprivation, but unlike that of a change in reinforcement magnitude.     

Relation between level of food deprivation and rate of schedule-induced attack

The relation between food deprivation and schedule-induced attack was investigated in four White Carneaux pigeons. Attack toward a mirror target was induced by a schedule of reinforcement in which 3-sec food presentations occurred at alternate intervals of 15 and 120 sec (multiple fixed-time 15-sec fixed-time 120-sec schedule). A continuous tone was presented during the 15-sec periods; it was absent during the 120-sec periods. Each pigeon was tested at 65, 80, and 95% of its free-feeding weight in ascending, descending, and ascending orders, respectively. Two relations were apparent; an inverse relation between body weight and rate of attack, and a tendency for rate of attack to increase during the experiment. Reduction or elimination of attack when the mirror was covered with brown paper for some sessions indicated that the results were due neither to changes in activity that might covary with weight nor to habituation to the experimental situation.     

Naturalistic Partial Sleep Deprivation Leads to Greater Next-Day Anxiety: The Moderating Role of Baseline Anxiety and Depression

The detrimental effects of insufficient sleep on emotional functioning have been well established. Total sleep deprivation usually leads to increased anxiety and depressive symptoms the following day. However, no study has yet examined the relationships between unmanipulated partial sleep deprivation and next-day symptoms of anxiety and depression in everyday life, which this study sought to characterize. Participants (N = 94) completed daily diary surveys twice per day for 2 weeks without instructions to alter their sleep in any way. Nights of spontaneous, naturally occurring partial sleep deprivation were followed by increased levels of self-reported symptoms of anxious arousal the next day, but were unrelated to next-day symptoms of anhedonic depression or general distress. The relationship between partial sleep deprivation and next-day anxious arousal was found to be moderated by both baseline depressive symptoms and anxiety such that individuals reporting higher levels of depression or anxiety at baseline showed relatively greater increases in symptoms of anxiety following partial sleep deprivation. These results suggest that partial sleep deprivation occurring in everyday life can lead to higher next-day levels of anxious arousal, a relationship that is particularly deleterious for individuals with higher overall levels of anxiety or depressive symptoms.     

A time series analysis of the relation between motor skill acquisition and sleep in infancy

To systematically examine the relation between motor milestone onset and disruption of night sleep in infancy, three families kept microgenetic, prospective, daily checklist diaries of their infants’ motor behavior and sleep (197-313 observation days; 19,000 diary entries). Process control and interrupted time series analyses examined whether deviations from the moving average for night wakings and evening sleep duration were temporally linked to motor skill onset and tested for meaningful differences in individual sleep patterns before and after skill onset. Model assumptions defined skill onset as first day of occurrence or as mastery and moving average windows as 3, 7, or 14 days. Changes in infants’ sleep patterns were associated with changing expertise for motor milestones. The temporal relation varied depending on infant and sleep parameter. Intensive longitudinal data collection may increase our understanding of micro-events in infant development.