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排序方式: 共有351条查询结果,搜索用时 15 毫秒
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Artemis Traikapi Ioanna Kalli Andrea Kyriakou Elena Stylianou Rafaella Tereza Symeou Akrivi Kardama Yiolanda Panayiota Christou Phivos Phylactou Nikos Konstantinou 《Journal of Neuropsychology》2023,17(2):279-301
Episodic memory decline is the prominent neuropsychological feature of typical Alzheimer's Disease (AD), for which current treatments have a limited clinical response. Recently, gamma entrainment therapy has been used as a non-invasive treatment in AD, providing evidence that it may have the potential to alleviate brain pathology and improve cognitive function in AD patients. At the same time, the precuneus (PC) has been recognized as a key area involved in AD related memory deficits and as a key node of the Default Mode Network. This study aimed to investigate the effectiveness of a 40 Hz Transcranial Magnetic Stimulation (TMS) intervention, delivered bilaterally to the precuneus for 10 days, in improving the patients' episodic memory performance. Secondary outcome variables investigated included general cognitive function, semantic and spatial memory, as well as attention and executive function. A concurrent multiple baseline design across five cases was employed. Four patients completed the study. Visual analysis combined with effect size indices were used to evaluate changes across phases. An increase in the average level of immediate recalled words was observed in three out of four patients. Effect size indices indicated significant improvement of attention skills in two patients. No treatment effect was observed for semantic and visual memory, or for executive function. An immediate treatment effect was observed in all patients' general cognitive function as assessed with the Alzheimer's Disease Assessment Scale (mean reduction of 5 points), which was maintained and improved further three months post-treatment. The neuropsychological evaluations indicated improved performance three months post-treatment in immediate and delayed recall, attention, phonological verbal fluency, anxiety, and neuropsychiatric symptoms. This study provides preliminary evidence for the efficacy of a novel non-pharmacological treatment using gamma-band TMS in addressing cognitive dysfunction in AD. 相似文献
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中国传统情绪疗法及其应用 总被引:13,自引:1,他引:12
系统地探讨了中国传统情绪疗法:情志相胜疗法,相反情绪疗法,激情刺激疗法,与感觉刺激有关的情绪疗法,与别人有关的情绪疗法,顺情从欲疗法,抑情顺理疗法,移情易性疗法,情志导引疗法,七情合参疗法。这些中国传统心理疗法在现代仍有实用价值。 相似文献
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Effect of delay-interval stimuli on delayed symbolic matching to sample in the pigeon 总被引:4,自引:4,他引:0 下载免费PDF全文
In Experiment 1, food-deprived pigeons received delayed symbolic matching to sample training in a darkened Skinner box. Trials began with the illumination of the grain feeder lamp (no food sample), or illumination of this lamp, accompanied by the raising of the feeder tray (food sample). After a delay of a few seconds, the two side response keys were illuminated, one with red and one with green light, with positions counterbalanced over trials. Pecking the red (green) comparison produced grain reinforcement if the trial had started with food (no food); pecking red after a no-food sample or green after a food sample was not reinforced. Once matching performance was stable, four stimuli were presented during the delay interval, and their effects on matching accuracy were evaluated. Both illumination of the houselight and the center key with white geometric forms decreased matching accuracy, whereas presentation of a tone and vibration of the test chamber did not. In Experiment 2, pecking the red center key was reinforced with food according to a variable interval schedule. The effects of occasional brief presentations of the four stimuli used in the first experiment on ongoing pecking were assessed. The houselight and form disturbed key pecking, but the tone and vibration did not. Thus, stimuli that interfered with delayed matching also interfered with simple operant behavior. Implications of these results for theories of remembering are discussed. 相似文献
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Economic substitutability of electrical brain stimulation, food, and water. 总被引:1,自引:0,他引:1 下载免费PDF全文
Concurrent variable-ratio schedules of electrical brain stimulation, food, and water were paired in various combinations as reinforcement of rats' lever presses. Relative prices of the concurrent reinforcers were varied by changing the ratio of the response requirements on the two levers. Economic substitutability, measured by the sensitivity of response ratio to changes in relative price, was highest with brain stimulation reinforcement of presses on both levers and lowest with food reinforcement of presses on one lever and water reinforcement of presses on the other. Substitutability with brain stimulation reinforcement of presses on one lever and either food or water reinforcement for presses on the other was about as high as with brain stimulation for presses on both levers. Electrical brain stimulation for rats may thus serve as an economic substitute for two reinforcers, neither of which is substitutable for the other. 相似文献
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前人研究表明自动情绪调节能够自上而下地影响情绪及情绪性注意过程。近来有研究提示自动情绪调节与眶额皮层(orbitofrontal cortex, OFC)有关。也有研究表明左侧OFC的激活影响负性注意偏向。本研究采用经颅直流电刺激技术,考察阈下启动情绪控制目标条件下,抑制左侧眶额皮层兴奋性是否影响负性注意偏向。结果发现,使用阴极刺激抑制左侧OFC活动可以加快被试对与恐惧刺激位置一致的探测点的反应。该结果提示左侧眶额皮层是自动情绪调节下情绪性注意选择相关的重要脑区。 相似文献
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This study investigated whether multisensory stimulation with other-race faces can reduce racial prejudice. In three experiments, the faces of Caucasian observers were stroked with a cotton bud while they watched a black face being stroked in synchrony on a computer screen. This was compared with a neutral condition, in which no tactile stimulation was administered (Experiment 1 and 2), and with a condition in which observers’ faces were stroked in asynchrony with the onscreen face (Experiment 3). In all experiments, observers experienced an enfacement illusion after synchronous stimulation, whereby they reported to embody the other-race face. However, this effect did not produce concurrent changes in implicit or explicit racial prejudice. This outcome contrasts with other procedures for the reduction of self-other differences that decrease racial prejudice, such as behavioural mimicry and intergroup contact. We speculate that enfacement is less effective for such prejudice reduction because it does not encourage perspective-taking. 相似文献
8.
The purpose of this study was to examine the effects of a cognitive stimulation program with games on scores to cognitive tests (processing speed, mental flexibility, working memory, inhibition) and how this program can benefit to a psycho-affective measure, self-esteem in older adults. Forty-eight participants over 60 years old took part in the experiment. They were divided into two groups: 1 group followed a program of cognitive stimulation using leisure activities with games and 1 control group in which people gathered every week. There were 8 sessions of cognitive stimulation using leisure activities like games, one-hour session a week. Measures have focused on speed of processing and executive functions (shifting, updating and inhibition). They have been evaluated before and after the training program. Results show that the cognitive stimulation program using leisure activities with games is effective on speed of processing, memory span, inhibition and self-esteem but shows no benefits on shifting and updating. These results indicate that it seems to be possible to enhance cognitive resources, inhibition and self-esteem using leisure activities with games as a tool for cognitive stimulation. 相似文献
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抑郁症患者的负性心境可能源于其抑制功能障碍。患者在主动遗忘负性材料时无法有效调用背外侧前额叶(the dorsolateral prefrontal cortex, DLPFC)等负责抑制控制的额叶脑网络。同时, 患者对社会信息的加工比对非社会信息的加工存在更明显的认知神经障碍, 很难主动遗忘对自己不利的社会反馈信息。为了提高抑郁症患者对负性社会反馈的主动遗忘能力, 本研究采用经颅磁刺激技术(transcranial magnetic stimulation, TMS), 考察抑郁症患者在左侧(n = 32)或右侧DLPFC (n = 30)被激活后其记忆控制能力的改变。结果表明, 当患者的DLPFC被TMS激活时, 他们对社会拒绝的回忆正确率与健康对照组(n = 31)无差异, 且TMS激活右侧DLPFC还改善了患者对他人的社会态度。本研究是采用TMS提高抑郁症患者主动遗忘能力的首次尝试, 研究结果不但支持了DLPFC与记忆控制功能的因果关系, 还为临床治疗抑郁症、创伤后应激障碍、药物成瘾等患者的记忆控制缺陷提供了明确的神经靶点。 相似文献
10.
We present an empirically supported theoretical and methodological framework for quantifying the system-level properties of person-plus-tool interactions in order to answer the question: “Are person-plus-tool-systems extended cognitive systems?” Nineteen participants provided perceptual judgments regarding their ability to pass through apertures of various widths while using visual information, blindfolded wielding a rod, or blindfolded wielding an Enactive Torch—a vibrotactile sensory-substitution device for detecting distance. Monofractal, multifractal, and recurrence quantification analyses were conducted to assess features of person-plus-tool movement dynamics. Trials where people utilized the rod or Enactive Torch demonstrated stable “self-similarity,” or indices of healthy and adaptive single systems, regardless of aperture width, trial order, features of the participants’ judgments, and participant characteristics. Enactive Torch trials exhibited a somewhat greater range of dynamic fluctuations than the rod trials, as well as less movement recurrence, suggesting that the Enactive Torch allowed for more exploratory movements. Findings provide support for the notion that person-plus-tool systems can be classified as extended cognitive systems and a framework for quantifying system-level properties of these systems. Implications concerning future research on extended cognition are discussed. 相似文献