De Finetti's earliest works on the foundations of probability

Bruno de Finetti's earliest works on the foundations of probability are reviewed. These include the notion of exchangeability and the theory of random processes with independent increments. The latter theory relates to de Finetti's ideas for a probabilistic science more generally. Different aspects of his work are united by his foundational programme for a theory of subjective probabilities.This work would not have been possible in its present form without the generous help of Prof. Maria Carla Galavotti. For several years, she has unfailingly answered all my requests for papers difficult of access, and discussed the details of interpretation as well as the philosophy of probability in general. To her I express my gratitude for everything.     

Pharmacological dissociation of memory: anisomycin, a protein synthesis inhibitor, and leupeptin, a protease inhibitor, block different learning tasks

Inhibition of protein synthesis by anisomycin for a short duration impairs memory of a one-trial inhibitory avoidance task in rats. Memory of escape conditioning involving eight trials is disrupted only if the duration of protein synthesis is prolonged by repeated injections. In marked contrast, olfactory memory of rats trained on two odor discriminations is not affected by anisomycin even if the duration of inhibition is prolonged and the number of trials is reduced to a minimum. In previous work, leupeptin, a thiol proteinase inhibitor, was shown to impair olfactory discrimination learning, but left inhibitory and avoidance conditioning intact. Together, these results provide a pharmacological double dissociation of memory, and suggest that the same chemistries, or mixtures of chemistries, may not be involved in all types of memory.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Barriers to Adult Career Change

Adults have unique problems in making career changes. They face crucial economic, educational, and psychological barriers that require special guidance services. In this article, barriers to adult career change are identified and a five-county regional learning service using paraprofessionals is described. Results in working with more than 200 adults making career changes is reported. Suggestions for overcoming some of the problems adults face in making career changes are explained.     

Additivity and expected utility in risky multiattribute preferences

This experiment analyzed human preferences among even chance gambles for commodity bundles. The purpose of the experiment was to test several independence assumptions that distinguish between models for risky multiattribute preferences. In particular, the additivity and the expected utility part of the additive expected utility model were tested symmetrically. The degree and form of model violations were established, and the effects of instructions and of response modes were examined. All independence assumptions were violated by a bias to prefer a gamble or a commodity bundle that was previously matched against a standard. Systematic and strong violations that superseded this bias questioned the validity of the additive expected utility model. In violation of the additivity part of that model subjects consistently preferred the gamble with more balanced outcomes when comparing gambles with identical marginal probability distributions. This trend, called multiattribute risk aversion, was independent of subjects' single attribute risk attitude. Instructions and response modes had no noticeable impacts on these response patterns.     

A vector graphic CRT display system

A vector graphic CRT display system for research in visual information processing is described. The vector graphic processor includes a 4K-byte display memory. The processor communicates with the controlling computer via a serial channel. The system is capable of exposure durations below 1 msec, and it allows on-line generation and modification of display files during an experiment. Brightness can be controlled separately for each vector of a picture. A graphic display editor in FORTRAN IV for interactive editing and debugging of display files has been developed.     

Perception of American sign language in dynamic point-light displays

Perception of dynamic events of American Sign Language (ASL) was studied by isolating information about motion in the language from information about form. Four experiments utilized Johansson's technique for presenting biological motion as moving points of light. In the first, deaf signers were highly accurate in matching movements of lexical signs presented in point-light displays to those normally presented. Both discrimination accuracy and the pattern of errors were similar in this matching task to that obtained in a control condition in which the same signs were always represented normally. The second experiment showed that these results held for discrimination of morphological operations presented in point-light displays as well. In the third experiment, signers were able to accurately identify signs of a constant handshape and morphological operations acting on signs presented in point-light displays. Finally, in Experiment 4, we evaluated what aspects of the motion patterns carried most of the information for sign identifiability. We presented signs in point-light displays with certain lights removed and found that the movement of the fingertips, but not of any other pair of points, is necessary for sign identification and that, in general, the more distal the joint, the more information its movement carries.     

A two-year follow-up study of a preventive mental health program for preschoolers

The long-term effects of a preschool intervention program for high-risk experimental children were assessed and compared to a high-risk placebo control group and low-risk normal controls. Seventy first-grade children were involved in this 2-year follow-up. The experimental treatment group was superior to that of the placebo control group at follow-up on the criteria measures of behavioral adjustment and achievement. The low-risk normal control group was significantly different from that of the placebo control groups, but generally not significantly different from that of the experimental groups, suggesting that the intervention had boosted the high-risk experimental treatment children to the point where their performance was comparable to that of children who had not experienced behavioral or learning difficulties.The study was supported by grants from the McGregor Fund and the Eloise and Richard Webber Foundation, and by the Detroit Public Schools, for which the authors express grateful appreciation. A version of this paper was presented at the Annual Meeting of the American Psychological Association, New York, September 1979.     

The treatment of epilepsies with Convulsofin

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.     

Choice reaction time with a random foreperiod

Choice reaction latencies were measured at three different a priori probabilities for two stimulus alternatives. Unlike the results of some other studies, the mean latency of a given response was nearly the same whether the response was correct or incorrect. The discriminable stimuli were a 1000- or a 1700-Hz tone presented at 70 dB SPL. Latencies and standard deviations, based on about 17,000 observations, are reported for three observers. The data are compared with predictions of the optimum sequential model of Wald and Stone and two modifications of that random-walk model, one proposed by Link and Heath and the other proposed by Laming. Fast-guess analyses were also carried out. The three-parameter version of either the sequential or the modified random-walk models provided reasonably accurate predictions of the mean data for each observer. The parameters estimated by the fast-guess analysis were unrealistic. There are three obvious differences between this experiment and most previous choice reaction-time experiments. First is stimulus modality#x2014;we used an auditory signal, whereas most of the previous studies used a visual signal. Second, the observers practiced more in this experiment than in most previous experiments. Finally, there was a random foreperiod with a heavy penalty for anticipations. One or more of these factors is the probable reason for the discrepancy between our results and those of previous studies.