Minds, persons, and space: an fMRI investigation into the relational complexity of higher-order intentionality

Mental state reasoning or theory-of-mind has been the subject of a rich body of imaging research. Although such investigations routinely tap a common set of regions, the precise function of each area remains a contentious matter. With the help of functional magnetic resonance imaging (fMRI), we sought to determine which areas are involved when processing mental state or intentional metarepresentations by focusing on the relational aspect of such representations. Using non-intentional relational representations such as spatial relations between persons and between objects as a contrast, the results ascertained the involvement of the precuneus, the temporal poles, and the medial prefrontal cortex in the processing of intentional representations. In contrast, the anterior superior temporal sulcus and the left temporo-parietal junction were implicated when processing representations that refer to the presence of persons in relational contexts in general. The right temporo-parietal junction, however, was specifically activated for persons entering spatial relations. The level of representational complexity, a previously unexplored factor, was also found to modulate the neural response in some brain regions, such as the medial prefrontal cortex and the right temporo-parietal junction. These findings highlight the need to take into account the critical roles played by an extensive network of neural regions during mental state reasoning.     

Circulating fibrinogen but not D-dimer level is associated with vital exhaustion in school teachers

Meta-analyses have established elevated fibrinogen and D-dimer levels in the circulation as biological risk factors for the development and progression of coronary artery disease (CAD). Here, we investigated whether vital exhaustion (VE), a known psychosocial risk factor for CAD, is associated with fibrinogen and D-dimer levels in a sample of apparently healthy school teachers. The teaching profession has been proposed as a potentially high stressful occupation due to enhanced psychosocial stress at the workplace. Plasma fibrinogen and D-dimer levels were measured in 150 middle-aged male and female teachers derived from the first year of the Trier-Teacher-Stress-Study. Log-transformed levels were analyzed using linear regression. Results yielded a significant association between VE and fibrinogen (p = 0.02) but not D-dimer controlling for relevant covariates. Further investigation of possible interaction effects resulted in a significant association between fibrinogen and the interaction term "VE x gender" (p = 0.05). In a secondary analysis, we reran linear regression models for males and females separately. Gender-specific results revealed that the association between fibrinogen and VE remained significant in males but not females. In sum, the present data support the notion that fibrinogen levels are positively related to VE. Elevated fibrinogen might be one biological pathway by which chronic work stress may impact on teachers' cardiovascular health in the long run.     

An Internet-Based Compassion-Focused Intervention for Increased Self-Criticism: A Randomized Controlled Trial

Increased levels of self-criticism and a lack of self-compassion have been associated with the development and maintenance of a range of psychological disorders. In the current study, we tested the efficacy of an online version of a compassion-focused intervention, mindfulness-based compassionate living (MBCL), with guidance on request. A total of 122 self-referred participants with increased levels of self-criticism were randomly assigned to care as usual (CAU) or the intervention group (CAU + online intervention). Primary endpoints were self-reported depressive, anxiety and distress symptoms (DASS-21) and self-compassion (SCS) at 8 weeks. Secondary endpoints were self-criticism, mindfulness, satisfaction with life, fear of self-compassion, self-esteem, and existential shame. At posttreatment, the intervention group showed significant changes with medium to large effect sizes compared to the control group regarding primary outcomes (Cohen’s d: 0.79 [DASS] and -1.21 [SCS]) and secondary outcomes (Cohen’s ds: between 0.40 and 0.94 in favor of the intervention group). The effects in the intervention group were maintained at 6-months postrandomization. Adherence measures (number of completed modules, self-reported number of completed exercises per week) predicted postintervention scores for self-compassion but not for depressive, anxiety, and distress symptoms in the intervention group. The current study shows the efficacy of an online intervention with a transdiagnostic intervention target on a broad range of measures, including depressive and anxiety symptoms and self-compassion.     

Beyond Hume: Demea a rehabilitation with systematic intent

International Journal for Philosophy of Religion - Traditionally, Demea is considered to be the weakest character in Hume’s famous Dialogues concerning Natural Religion; the stage is...     

Children's metamemorial judgments in an event recall task

Two studies were conducted in which two different indicators of metacognitive monitoring were investigated in a complex everyday memory task. In the first phase of each experiment, 8- and 10-year-olds as well as adults were shown a short event (video) and gave judgments of learning, that is, rated their certainty that they would later be able to recall specific details correctly. In the second phase of the experiments, participants underwent a memory interview about the event and in Study 2 also gave confidence judgments, that is, rated their certainty that the provided answers to the memory questions were correct. Results revealed significant influences of memory characteristics on monitoring in that delaying judgments and monitoring judgments concerning irretrievable information affected judgments of learning. From 8 years of age onward, there were relatively appropriate metamemorial monitoring abilities in both indicators. Moderate intraindividual consistency was found across the two measures of metacognitive monitoring, with a tendency toward higher consistency in older age groups. The results are discussed in terms of the adequacy of the underlying theoretical construct.     

Trajectories of maternal depressive symptoms, maternal sensitivity, and children's functioning at school entry

Using data from the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development, the authors modeled trajectories of maternal depressive symptoms from infant age 1 month to 7 years. The authors identified 6 trajectories of maternal depressive symptoms: high-chronic, moderate-increasing, high-decreasing, intermittent, moderate-stable, and low-stable. Women on these depression trajectories varied in sociodemographic risk and in changes in observed maternal sensitivity over time. Maternal sensitivity was generally higher and increased when depressive symptoms were low; sensitivity was lower and decreased when depressive symptoms were either high or increasing. Child outcomes at 1st grade were examined by trajectory group. The authors discuss the complexity of disentangling maternal symptoms from maternal sensitivity and sociodemographic risk when predicting children's functioning.     

Validation of the SASB Introject Surface in a Norwegian clinical and nonclinical sample

In this study, we examined the reliability and construct validity of the Structural Analysis of Social Behavior Introject Surface, Intrex long form A (SASB-IS; Benjamin, 1995) in 2 Norwegian samples. The fit of the 8 SASB-IS scales to the structural requirements of a circumplex model with relaxed equal spacing constraints was reasonably good in an outpatient sample, but poor in a normal reference sample. The deviations from the equal spacing based on an ideal circumplex model, however, seem to have minimal implications for the utility of the instrument in clinical assessment. The reliability of the SASB-IS was acceptable on most scales, but two scales had unacceptable low reliability. Correspondence with external criteria supported the validity of the SASB-IS in both samples. Profile patterns related to different segments of the introject circumplex model were systematically related to severity of psychopathology: Hostile and accepting patterns of self-relatedness formed polar opposites; control patterns and intermediate patterns gave intermediate pathology scores.     

Top-down inhibition of search distractors in parallel visual search

In three experiments, we examined distractor inhibition in parallel ("pop-out") visual search. Distractor inhibition was measured in terms of reaction time (RT) to a simple luminance increment probe presented, after the search task response, at display locations that either contained a search distractor (on-probe) or were blank (off-probe). When the search stimuli remained in view, the on-probe (relative to off-probe) RT cost was larger than in a baseline condition in which observers had only to passively view, rather than search, the display. This differential on-probe RT cost, which discounts effects of masking, was interpreted as a measure of distractor inhibition associated with target selection in parallel visual search. Taken together, the results argue that the distractor inhibition is an object-based and local phenomenon that affects all distractors (of a particular type) in an equal manner.     

Experimental comparison of dyspnea and pain

Dyspnea and pain are similarly unpleasant, alarming physical sensations, but studies examining both sensations in combination are lacking. In the present study, dyspnea was induced in 7 healthy volunteers by breathing through inspiratory resistive loads and the effects were compared with those of a heat pain stimulus. End-tidal partial pressures of carbon dioxide (PET_CO2), inspiratory time (Ti), breathing frequency (f), experienced unpleasantness, and intensity were measured. No difference was observed between dyspnea and pain in experienced intensity and unpleasantness (p >.05). During dyspneic stimulation, slightly higherTi was found than for pain (p<.08). PET_CO2 showed slight increases during the dyspneic versus the baseline and painful conditions (ΔPET_CO2=1.5 and 1.3 mmHg, respectively;p<.01 andp<.05). This study shows that the effects of dyspnea and heat pain can be compared within one experiment; both stimuli can be presented with similar intensity and unpleasantness, which is a prerequisite for comparing responses to them. The changes in PET_CO2 between our conditions were minimal, allowing an application of the present design to future fMRI studies.     

The time course of attentional and oculomotor capture reveals a common cause

Eye movements are often misdirected toward a distractor when it appears abruptly, an effect known as oculomotor capture. Fundamental differences between eye movements and attention have led to questions about the relationship of oculomotor capture to the more general effect of sudden onsets on performance, known as attentional capture. This study explores that issue by examining the time course of eye movements and manual localization responses to targets in the presence of sudden-onset distractors. The results demonstrate that for both response types, the proportion of trials on which responses are erroneously directed to sudden onsets reflects the quality of information about the visual display at a given point in time. Oculomotor capture appears to be a specific instance of a more general attentional capture effect. Differences and similarities between the two types of capture can be explained by the critical idea that the quality of information about a visual display changes over time and that different response systems tend to access this information at different moments in time.