Development and Pilot Testing of a Decision Aid for Genomic Research Participants Notified of Clinically Actionable Research Findings for Cancer Risk

Germline genomic testing is increasingly used in research to identify genetic causes of disease, including cancer. However, there is evidence that individuals who are notified of clinically actionable research findings have difficulty making informed decisions regarding uptake of genetic counseling for these findings. This study aimed to produce and pilot test a decision aid to assist participants in genomic research studies who are notified of clinically actionable research findings to make informed choices regarding uptake of genetic counseling. Development was guided by published literature, the International Patient Decision Aid Standards, and the expertise of a steering committee of clinicians, researchers, and consumers. Decision aid acceptability was assessed by self-report questionnaire. All 19 participants stated that the decision aid was easy to read, clearly presented, increased their understanding of the implications of taking up research findings, and would be helpful in decision-making. While low to moderate levels of distress/worry were reported after reading the booklet, a majority of participants also reported feeling reassured. All participants would recommend the booklet to others considering uptake of clinically actionable research findings. Results indicate the decision aid is acceptable to the target audience, with potential as a useful decision support tool for genomic research participants.     

Emotional Separation,Autonomy in Decision-Making,and Psychosocial Adjustment in Adolescence: A Proposed Typology

Adolescence is critical for learning autonomous behavior; however, little research is available on the most appropriate balance of the emotional and behavioral dimensions of autonomy for psychosocial adjustment during this period. In this study we present a novel autonomy typology that combines both these aspects, which can be implemented as autonomy in decision-making and emotional separation. Specifically, examined age differences in emotional separation and autonomy in decision-making during adolescence. We also assessed differences in psychosocial adjustment associated with profiles of autonomy typology, sex, and age. The participants were 567 adolescents (296 males and 271 females), aged between 12 and 18 years (M?=?14.48; SD?=?1.69), recruited in Spanish high schools. Each participant filled out questionnaires on identity commitment, self-esteem, emotional separation and autonomy in decision-making. The results showed that the most advantageous autonomy profile is ‘autonomous in decisions’ (those showing low emotional separation combined with autonomous behavior in decisions) which was associated with higher levels of self-esteem and occupational and ideological identity commitment. In addition, we also concluded that the balance of autonomy affects adjustment throughout adolescence, although early adolescence may be an especially critical period.     

Validation of the Visual Analogue Scale for Anxiety-Revised and school refusal across anxiety profiles

Background/Objectives

This paper aimed to validate the Spanish version of scores of the Visual Analogue Scale for Anxiety-Revised (VAA-R) in child population, and to verify the existence of anxiety profiles and to relate them to school refusal.

Event Semantics: A Husserlian Critique

Event semantics is concerned with the formal structure of sentences which appear to describe an event of some kind, e.g. ‘Brutus kills Caesar,’ or ‘My tooth fell out.’ Phenomenologists should be interested in work in this field, if they hope to rescue Husserl’s phenomenology of judgment from its narrow focus on copular judgments of the form ‘S is p.’ An adequate phenomenology of judgment must ultimately develop an account of judgments whose intentional correlates seem to be events, rather than states of affairs, since such judgments are ubiquitous. For this endeavor, existing work on the formal structure of event sentences provides a crucial foothold. However, phenomenologists cannot simply import semantic theories for their own use, without first evaluating them for phenomenological plausibility. This concern is particularly acute in the case of the widely-adopted “Davidsonian” approach, according to which the logical structure of event sentences diverges radically from natural language syntax. The Davidsonian form introduces a “covert” variable, which stands in for an event. Thus, the sentence ‘Brutus kills Caesar’ becomes, ‘There is an event e that is a killing of Caesar by Brutus.’ Such a theory, if correct, would have decisive consequences for the phenomenology of event sentences, and even of events themselves. Yet the introduction of covert variables in turn introduces—I argue—a covert intentional object, without assessing this idea for phenomenological plausibility. Building on Husserl’s phenomenology of predication, I develop a criterion for evaluating this hypothesis, and argue that the Davidsonian approach, as it stands, is phenomenologically untenable.     

The future is now: the impact of present fluency in judgments about the future

Recent research has emphasised the role of episodic memory in both remembering past events and in envisaging future events. On the other hand, it has been repeatedly shown that judgments about past events are affected by the fluency with which retrieval cues are processed. In this paper we investigate whether perceptual fluency also plays a role in judgments about future events. For this purpose we conducted four experiments. The first experiment replicated recent findings showing that stimuli that are processed fluently tend to be wrongly recognised as having been encountered in the past outside the laboratory walls [Brown, A. S., & Marsh, E. J. (2009). Creating illusions of past encounter through brief exposure. Psychological Science, 20, 534–538. doi:10.1111/j.1467-9280.2009.02337.x]. Two follow-up experiments using Brown and Marsh’s [(2009). Creating illusions of past encounter through brief exposure. Psychological Science, 20, 534–538. doi:10.1111/j.1467-9280.2009.02337] task tested the influence of perceptual fluency on future judgments. The fourth and last experiment was designed to rule out a potential confounding factor in the two previous experiments. Across experiments, we found that people rely on fluency when making judgments about events that are yet to come. These results suggest that fluency is an equally valid cue for past and future judgments.     

Trust within Limits

Abstract

There have two recent challenges to the orthodoxy that ‘X trusts Y to ø’ is the fundamental notion of trust. Domenicucci and Holton maintain that trust, like love and friendship, is fundamentally two-place. Paul Faulkner argues to the more radical conclusion that the one-place ‘X is trusting’ is explanatorily basic. I argue that ‘X trusts Y in domain D’ is the explanatorily basic notion. I make the case that only by thinking of trust as domain-specific can we make sense of the relationships between trust and belief in goodwill, trust and distrust, and trust and trustworthiness. In addition, by modeling trust as essentially domain-specific we can account for the way in which wise trust in others is finely discriminating.     

Reducing behavioural risk factors for cancer: An affect regulation perspective

Nearly half of all cancer deaths are attributable to preventable causes, primarily unhealthy behaviours such as tobacco use, alcohol use and overeating. In this review, we argue that people engage in these behaviours, at least in part, as a means of regulating their affective states. To better understand why people engage in these behaviours and how researchers might design interventions to promote the selection of healthier methods for regulating affect, we propose a conceptual model of affect regulation. We synthesise research from both the stress and coping tradition as well as the emotion and emotion regulation tradition, two literatures that are not typically integrated. In so doing, we indicate where researchers have made headway in understanding these behaviours as affect regulation and note how our model could be used to structure future work in a way that would be particularly advantageous to cancer control efforts.