Mr. Grimace or Ms. Smile: does categorization affect perceptual processing in autism?

This study compared the influence of categorization on perceptual processing in adults with autistic spectrum disorders (ASD) and normal control participants. Participants were asked to categorize hybrid faces (composed of two overlapped faces of different spatial bandwidths) by gender and emotion. Control participants exhibited a bias for low-pass information during gender categorization and a bias for high-pass information during emotion categorization. By contrast, adults with ASD showed the same low-pass bias in both tasks. This absence of a shift in processing style in the ASD group is discussed in terms of diminished top-down modulation in autism.     

The effects of different intensity levels of background noise on dichotic listening to consonant-vowel syllables

It has previously been shown that the right ear advantage in dichotic listening to consonant-vowel syllables is affected if a background noise is presented at the same time as the dichotic stimuli. What is not known is, however, if there is also an effect of varying the intensity level of the background noise. We therefore presented conversation or traffic noise background noise simultaneously with the dichotic syllable stimuli to healthy adult subjects. The intensity of the background noises varied between 50-65 dB in steps of 5 dB. The results showed that the right ear correct reports decreased, while left ear correct reports increased as a consequence of increasing background noise intensity. The effects were also stronger for the right ear, and for the traffic background noise condition, particularly at the two highest intensity levels. The results are discussed in terms of alertness and attentional mechanisms.     

卫生保健的伦理教学:寻求一种新的教育学

鉴于要使全球性的生命伦理学包括边缘化人群进入主流社会,一个重要方面就是重构教育学.通过这种重构,伦理语境从一代代的医学专业人士或社会/医学研究者中复制出来.我们当前的伦理学教学是哲学的,从理性的观点来看,这不是奇怪的.如果伦理学教学方法本身是家长主义的,这种伦理学教学如何传递文化上的多种声音或真理的相对性?     

Preterm birth affects dorsal-stream functioning even after age 6

With increasing numbers of preterm infants surviving, the impact of preterm birth on later cognitive development presents a major interest. This study investigates the impact of preterm birth on later dorsal- and ventral-stream functioning. An atypical pattern of performance was found for preterm children relative to full-term controls, but in the dorsal-drawing task only. These findings suggest that the number of gestational weeks does affect dorsal-stream functioning, even after more than 6 years of favorable environmental conditions in healthy preterm children.     

Benefits of physical exercise on executive functions in older people with Parkinson’s disease

The benefits of physical exercise on cognitive functioning have been reported in the literature, but the potential benefits to slow the eventual decline in executive functioning (EF) caused by neurodegeneration from Parkinson’s Disease (PD) have rarely been studied. Thus the objective of this study was to analyze the effects of a multimodal physical exercise program on EF in older people with Parkinson’s disease. The EF of the older people was evaluated by neuropsychological testing, and for confounding variables such as attention, depressive symptoms and anxiety, before and after intervention. The 20 participants were assigned into Control (CG) and Trained (TG) Groups. The TG participated in generalized physical training for 6 months. The ANOVA showed a significant interaction (p < .05) that indicated a beneficial contribution of training on EF. No significant interactions were found in the results for confounding variables between groups and pre- and post-intervention, which supports the beneficial findings of physical exercise training on EF.     

The Effects of a Mental Health Video on the Social Skills Knowledge and Attitudes of Mexican Immigrants1

The purpose of this study was to evaluate the effects of a Spanish mental health video, “Cuida Su Salud Mental”, on the relationship attitudes and social skills knowledge of a Mexican immigrant sample. Subjects consisted of 72 Spanish speaking English as a second language (ESL) students recruited from the Paramount Adult School, in the county of Los Angeles. The Solomon (1949) Four Group Design was used. Half of the subjects were pretested on knowledge and attitudes about effective communication skills and relationships, respectively. All subjects view either the mental health video or a control video, and then were posttested on knowledge and attitudes. Results indicated that the mental healthy video (MHV) group exhibited more knowledge, F(1, 62) = 10.61, p= 0.002, and less risky attitudes, F(1, 62) = 4.29, p= 0.043, than the control video group. The MHV group also showed an increase in knowledge from the pretest to the posttest, F(1, 35) = 7.36, p= 0.01. Finally, both video groups reported a decrease in risky attitudes from pretest to posttest, F(1, 34) = 18.21, p= 0.001. These results support the use of “Cuida Su Salud Mental” as a productive and cost-effective mental health intervention that can be used to reach a large segment of the Spanish speaking community.     

Hey Buddy,Can You Spare Seventeen Cents? Mindful Persuasion and the Pique Technique1

According to the pique technique, a target is more likely to comply if mindless refusal is disrupted by a strange or unusual request. We demonstrated the use of this technique in two experiments. In Experiment 1, passersby on a local municipal wharf were approached by a confederate panhandler who made either one of two strange requests: “Can you spare 17¢ (or 37¢)?” or made either one of two typical requests “Can you spare a quarter (or any change)?” Subjects in the strange conditions were almost 60% more likely to give money than those receiving the typical plea. In addition, a strange request piqued interest as evidenced by increased verbal inquiries about the request. Experiment 2 replicated the first experiment in a laboratory setting and provides additional evidence (via a cognitive response analysis) that strange requests piqued subjects' interest in the appeal as well as increased liking for the panhandler.     

Stress and cardiac beta adrenoceptors

Most modern theories about stress recognize that although stress is not a disease, it may be the trigger for the majority of diseases when allostatic overload has been generated. During stress, the glucocorticoids and catecholamines play a key role in the regulation of physiological parameters and homeostasis during stress. In the heart, positive chronotropic, inotropic, and lusitropic responses to catecholamines are mediated by various subtypes of adrenergic receptors (beta-ARs), mainly beta1- and beta2-adrenergic receptors. beta-ARs also control cardiomyocyte growth and death, thus contributing to cardiac remodelling. The structural basis of each beta-AR subtype, as well as their signalling pathways, and adaptive responses to stress are discussed. The participation of beta3- and putative beta4-ARs in the control of cardiac function is also discussed, with emphasis on low affinity beta-AR isoforms and the role they play in the response to the catecholamines under stress. The changes in beta-AR signalling under pathogenic conditions as well as under stress are reviewed.     

The association of macro- and microstructure of the corpus callosum and language lateralisation

The present study aimed to examine how differences in functional lateralisation of language are related to interindividual variations in interhemispheric connectivity. Utilising an fMRI silent word-generation paradigm, 89 left- and right-handed subjects were subdivided into four lateralisation subgroups. Applying morphological and diffusion-tensor MRI, midsagittal cross-sectional area as well as quantitative measures of molecular diffusion (anisotropy, mean diffusion) of the corpus callosum were determined to assess interhemispheric connectivity. Statistical analyses revealed group differences in molecular diffusion but not in callosal size, which may be interpreted to reflect a stronger and/or faster interhemispheric connection in strongly left-lateralised subjects as compared to moderately left-lateralised, bilateral, or moderately right-lateralised subjects.