Large-scale ensemble averaging of ambulatory impedance cardiograms

Impedance cardiography has been used increasingly to measure human physiological responses to emotional and mentally engaging stimuli. The validity of large-scale ensemble averaging of ambulatory impedance cardiograms was evaluated for preejection period (PEP), interbeat interval, and dZ/dt_(min) amplitude. We tested whether the average of “classical” 60-sec ensemble averages across periods with fixed activity, posture, physical load, social situation, and location could be accurately estimated from a single large-scale ensemble average spanning these entire periods. Impedance and electrocardiograms were recorded for about 24-h from 21 subjects. Recordings were scored by seven raters, using both methods for each subject. Good agreement (average intraclass correlation coefficient was .91) between both ensemble averaging methods was found for all three cardiac function measures. The results indicate that for unambiguous ambulatory impedance cardiograms, large-scale ensemble averaging is valid, which makes measuring prolonged changes in cardiac sympathetic activity by measuring ambulatory PEP feasible even in large epidemiological samples.     

Changes in executive control across the life span: examination of task-switching performance

A study was conducted to examine changes in executive control processes over the life span. More specifically, changes in processes responsible for preparation and interference control that underlie the ability to flexibly alternate between two different tasks were examined. Individuals (N = 152) ranging in age from 7 to 82 years participated in the study. A U-shaped function was obtained for switch costs (i.e., the time required to switch between tasks compared with a repeated-task baseline), with larger costs found for young children and older adults. Switch costs were reduced with practice, particularly for children. All age groups benefited from increased preparation time, with larger benefits observed for children and older adults. Adults benefited to a greater extent than children when the interval between the response to one task and the cue indicating which task to perform next was lengthened, which suggested faster decay of interference from the old task set for adults than for children. A series of hierarchical analyses indicated that the age-related variance in task-switching performance is independent, at least in part, from the age-related variance in other cognitive processes such as perceptual speed and working memory. The results are discussed in terms of the development and decline of executive control processes across the life span.     

Effect of inapplicable items in the factor structure of the Spanish version of the Ways of Coping Questionnaire

The aim of this work was to examine how the presence of inapplicable items might change the factor structure of the 1984 Ways of Coping Questionnaire by Lazarus and Folkman. The Spanish version of the Ways of Coping Questionnaire was administered to 156 subjects with university degrees. The 95 women and 61 men whose ages were from 18 and 45 years (M = 27.8, SD = 12.1) were of middle socioeconomic status. All were residents of Buenos Aires. To study whether relevant items modify the factor structure of the Ways of Coping Questionnaire, two factor analyses were carried out, one with items rated as not relevant (Item Mean) and the other with the same items rated as not chosen. In both factor analyses, principal axes method and oblimin rotation were performed, and five factors were considered. Congruence indexes were performed. Analysis showed that not choosing an item because it does not coincide with one's behavior or ideas is not the same as not selecting that item because it does not apply to the current threatening situation. Lack of discrimination between situations when analyzing data leads to a distorted interpretation of the way in which the subject actually behaves or copes with the situation.     

Quality of life before and after lung transplantation in patients with emphysema versus other indications

Whether lung transplantation improves Health-related Quality of Life in patients with emphysema and other end-stage lung diseases before and after lung transplantation was examined. Between 1992 and 1999, 23 patients with emphysema and 19 patients with other indications completed self-administered questionnaires before lung transplantation, and at 4, 7, 13, and 25 mo. after transplantation. The questionnaire included the Nottingham Health Profile, the State-Trait Anxiety Inventory, the Self-rating Depression Scale, the Index of Well-being, the self-report Karnofsky Index, and four respiratory-specific questions. Neither before nor after transplantation were significant differences found on most dimensions of Health-related Quality of Life between patients with emphysema and other indications. Before transplantation, both groups report major restrictions on the dimensions Energy and Mobility of the Nottingham Health Profile, low experienced well-being, depressive symptoms, and high dyspnea. About 4 mo. after transplantation, most Health-related Quality of Life measures improved significantly in both groups. These improvements were maintained in the following 21 mo.     

Functional recovery of skilled forelimb use in rats obliged to use the impaired limb after grafting of the frontal cortex lesion with homotopic fetal cortex

The long-term effect of transplanting embryonic frontal cortex into a unilateral frontal cortex lesion has been studied in adult rats. Before surgery, activity in an open field, muscular strength of both forelimbs, and performance in a paw-reaching-for-food task were scored in 26 rats. In 21 animals a unilateral cortex lesion was then made in the forelimb motor area of the hemisphere contralateral to the preferred paw in the paw-reaching-for-food task, while the other 5 animals were sham-operated. On retesting, the lesion animals changed the preferred paw. A solid homotopic transplant of embryonic tissue (embryonic day 17) was then placed in the lesion cavity in 11 of the lesion rats. Three months later neither lesion alone nor lesion plus transplantation affected open field behavior and muscular strength, but the lesion permanently affected performance in the paw-reaching-for-food task, as shown by a change of preferred paw and a functional deficit in the paw contralateral to the lesion. Transplantation ameliorated the deficits caused by the lesion, but this was only evident when animals were forced to reach with the paw contralateral to the lesion plus transplant. The behavioral results were independent of the size of the lesion and graft. Connections between graft and host tissue were studied by means of the fluorescent tracer 1,1'-dioctadecyl-3,3,3'3'-tetramethylindocarbocyanine perchlorate (DiI). A dense array of labeled fibers was found in the host cortex adjacent to the transplant. The results suggest that functional recovery depends on grafting but is only evident when the animal is obliged to use the affected limb.     

Ethics and engineering courses at Delft University of Technology: Contents, educational setup and experiences

This article reports on the development and teaching of compulsory courses on ethics and engineering at Delft University of Technology (DUT). Attention is paid to the teaching goals, the educational setup and methods, the contents of the courses, involvement of staff from engineering schools, experiences to date, and challenges for the future. The choices made with respect to the development and teaching of the courses are placed within the European and Dutch context and are compared and contrasted with the American situation and experiences. Previous versions of this article were presented at the meeting of the SEFI Working Group on Engineering Ethics in Rzeszow, Poland, April 29–May 1, 1999 and at the SEFI Annual Conference in Zurich, Switzerland, September 1–3, 1999.     

Towards a research programme for ethics and technology

In this editorial contribution, two issues relevant to the question, what should be at the top of the research agenda for ethics and technology, are identified and discussed. Firstly: can, and do, engineers make a difference to the degree to which technology leads to morally desirable outcomes? What role does professional autonomy play here, and what are its limits? And secondly, what should be the scope of engineers' responsibility; that is to say, on which issues are they, as engineers, morally obliged to reflect? The research agendas proposed by the authors contributing to this special section, implicitly, give different answers to these questions. We suggest that an explicit discussion of these issues would greatly help in constructing a common research agenda.     

Stronger suboptimal than optimal affective priming?

The finding of stronger affective priming in less conscious (suboptimal) conditions than in fully conscious (optimal) conditions (S. T. Murphy & R. B. Zajonc, 1993) is theoretically important because it contradicts notions that emotions are primarily reflected by conscious states. In 2 experiments, this pattern of results was obtained. Happy and angry faces were presented both optimally and suboptimally and were masked by unknown ideographs. In Experiment 1, instructions for the conscious and less conscious affective priming conditions were matched, and affective ratings of ideographs were determined. In Experiment 2, a more implicit affective measure (facial electromyography of musculus zygomaticus major and musculus corrugator supercilii) served as the dependent variable. Stronger suboptimal than optimal affective priming was found in both experiments. It is concluded that stronger suboptimal than optimal processing is characteristic for affective processing and that it can also be found when instructions are matched and when a more implicit measure is assessed.     

How tree shrews (Tupaia belangeri) perform in a searching task: evidence for strategy use

This study investigated how male tree shrews (Tupaia belangen) performed in a searching task while in their home cages and assessed whether different food distributions affected their performance. The animals were faced with a holeboard containing 9 food sources arranged in a 3 x 3 matrix or in 3 clusters, each containing 3 sources. Animals tended to start and end the trials from preferred locations, thereafter solving the task by strategically organizing the reward collection according to a minimum-distance principle. In the cluster configuration, they visited the sources hierarchically. Food distribution did not affect the performance. Comparison with data from mice and capuchin monkeys revealed that tree shrews and capuchins solved the task in a similar strategic way, whereas mice did not. These findings attract particular attention because of the phylogenetic position of tree shrews, which are regarded as closely related to primates.     

A satisfied clientele seeking more diverse services: Latinos and the courts

This article assesses Latino views of the court system, both of their beliefs about the courts and their experiences with the courts. Relying primarily on the Latino over-sample of the National Center for State Courts (2000) survey of public attitudes toward the courts, we evaluate three aspects of the Latino-judicial relationship. First, we measure whether there are differences between Latino and non-Latino views of the courts. Second, we assess whether there are differences within the Latino community, particularly differences based on nativity, in Latino attitudes toward the courts. Finally, we assess the implications of Latino views of the courts for US society in general. We are particularly concerned about whether having a greater share of Latinos in the population will create new pressures to reform the judiciary.