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121.
de Oliveira AR Reimer AE de Macedo CE de Carvalho MC Silva MA Brandão ML 《Neurobiology of learning and memory》2011,95(1):37-45
Excitation of the mesocorticolimbic pathway, originating from dopaminergic neurons in the ventral tegmental area (VTA), may be important for the development of exaggerated fear responding. Among the forebrain regions innervated by this pathway, the amygdala is an essential component of the neural circuitry of conditioned fear. The functional role of the dopaminergic pathway connecting the VTA to the basolateral amygdala (BLA) in fear and anxiety has received little attention. In vivo microdialysis was performed to measure dopamine levels in the BLA of Wistar rats that received the dopamine D(2) agonist quinpirole (1 μg/0.2 μl) into the VTA and were subjected to a fear conditioning test using a light as the conditioned stimulus (CS). The effects of intra-BLA injections of the D(1) antagonist SCH 23390 (1 and 2 μg/0.2 μl) and D(2) antagonist sulpiride (1 and 2 μg/0.2 μl) on fear-potentiated startle (FPS) to a light-CS were also assessed. Locomotor performance was evaluated by use of open-field and rotarod tests. Freezing and increased dopamine levels in the BLA in response to the CS were both inhibited by intra-VTA quinpirole. Whereas intra-BLA SCH 23390 did not affect FPS, intra-BLA sulpiride (2 μg) inhibited FPS. Sulpiride's ability to decrease FPS cannot be attributed to nonspecific effects because this drug did not affect motor performance. These findings indicate that the dopamine D(2) receptor pathway connecting the ventral tegmental area and the basolateral amygdala modulates fear and anxiety and may be a novel pharmacological target for the treatment of anxiety. 相似文献
122.
123.
Aznar-Casanova JA Matsushima EH Ribeiro-Filho NP Da Silva JA 《The Spanish journal of psychology》2006,9(2):273-284
The aim of this study is twofold: on the one hand, to determine how visual space, as assessed by exocentric distance estimates, is related to physical space. On the other hand, to determine the structure of visual space as assessed by exocentric distance estimates. Visual space was measured in three environments: (a) points located in a 2-D frontoparallel plane, covering a range of distances of 20 cm; (b) stakes placed in a 3-D virtual space (range = 330 mm); and (c) stakes in a 3-D outdoors open field (range = 45 m). Observers made matching judgments of distances between all possible pairs of stimuli, obtained from 16 stimuli (in a regular squared 4 x 4 matrix). Two parameters from Stevens' power law informed us about the distortion of visual space: its exponent and its coefficient of determination (R2). The results showed a ranking of the magnitude of the distortions found in each experimental environment, and also provided information about the efficacy of available visual cues of spatial layout. Furthermore, our data are in agreement with previous findings showing systematic perceptual errors, such as the further the stimuli, the larger the distortion of the area subtended by perceived distances between stimuli. Additionally, we measured the magnitude of distortion of visual space relative to physical space by a parameter of multidimensional scaling analyses, the RMSE. From these results, the magnitude of such distortions can be ranked, and the utility or efficacy of the available visual cues informing about the space layout can also be inferred. 相似文献
124.
Da Silva JA Matsushima EH Aznar-Casanova JA Ribeiro-Filho NP 《The Spanish journal of psychology》2006,9(2):285-294
The main purpose of the present study was to investigate whether in natural environment, using very large physical distances, there is a trend to overconstancy for distance estimates during development. One hundred and twenty-nine children aged 5 to 13 years old and twenty-one adults (in a control group), participated as observers. The observer's task was to bisect egocentric distances, ranging from 1.0 to 296.0 m, presented in a large open field. The analyses focused on two parameters, constant errors and variable errors, such as measuring accuracy and precision, respectively. A third analysis focused on the developmental pattern of shifts in constancy as a function of age and range of distances. Constant error analysis showed that there are two relevant parameters for accuracy, age, and range of distances. For short distances, there are three developmental stages: 5-7 years, when children have unstable responses, 7-11, underconstancy, and 13 to adulthood, when accuracy is reached. For large distances, there is a two-stage development: 5-11 years, with severe underconstancy, and beyond this age, with mild underconstancy. Variable errors analyses indicate that precision is noted for 7 year-old children, independently of the range of distances. The constancy analyses indicated that there is a shift from constancy (or slightly overconstancy) to underconstancy as a function of physical distance for all age groups. The age difference is noted in the magnitude of underconstancy that occurs in larger distances, where adults presented lower levels of underconstancy than children. The present data were interpreted as due to a developmental change in cognitive processing rather than to changes in visual space perception. 相似文献
125.
126.
The study explored the association between the perceptions 175 Chilean business students held about their parents' acceptance of academic dishonesty and their self-reports of academic dishonesty. Regressing scores for parental acceptance onto self-reported academic dishonesty indicated it accounted for a small (2.2%) but significant amount of variance beyond demographic and academic performance variables. Effect size analysis based on structure coefficients indicated that parental acceptance was the second best predictor in the equation, suggesting that parental acceptance is a correlate that merits further study. 相似文献
127.
T M Nelson T H Nilsson D J Piercey T Johnson J Frascara S Silva Delano E Susuki Sone M Villalon Bravo 《Perceptual and motor skills》1999,88(2):515-530
Information about letters and the physical structure of language printed in Roman characters was given to children beginning to read. Experimental investigations coupled three alternative graphic modes of printing upper- and lower-case letters with an instructional intervention termed "Alpha-Beta" which provides practice in letter sorting, matching of letters, associative matching, and memory matching. In respect to graphics, Mode A letters were in standard alphabet form. Mode B provided standard letters with each backed by a unique half-tone (Visually Stippled Alphabet); Mode C provided standard letters with each backed by a unique visual texture (Visually Patterned Alphabet). Pre-posttest change in reading readiness was measured using the Metropolitan Readiness Test. In the first study 224 English-speaking 5- to 6-yr.-old children were tested. In the second there were 158 Spanish-speaking girls and boys 6 to 7 years old. It was predicted that Alpha-Beta intervention involving visually patterned alphabet would lead to the greatest increases in readiness scores. This is confirmed in both studies for children low in reading readiness preexperiment. Children high in reading readiness are less affected. The second experiment involved Spanish-speaking children and investigated intervention by Alpha-Beta against a no-intervention control. This confirms the value of Alpha-Beta per se. Possible explanations for the improvements are identified. 相似文献
128.
Geners Ortet Manuel I. Ibez Micaela Moro Fernando Silva Gregory J. Boyle 《Personality and individual differences》1999,27(6):990
Psychometric characteristics of Eysenck's revised P scale were studied in a cross-cultural research. The Spanish version of the Eysenck Personality Questionnaire-Revised (EPQ-R) was administered to a Spanish sample of 527 males and 583 females. Maximum-likelihood factor analyses of the item intercorrelations and Direct Oblimin rotations of the extracted factors were carried out separately for males and females. The results revealed four factors identified as psychoticism (P), extraversion (E), neuroticism (N) and dissimulation/conformity (L). Internal consistency and test–retest reliability coefficients were satisfactory and very similar to the ones found in the original study. Skewness and kurtosis of the P scale distribution were closer to normal than on the original British revised P scale. 相似文献
129.
Francisco J. Silva 《Behavior research methods》1999,31(1):63-73
Shaping, or the method of successive approximations, is widely taught in introductory psychology and the psychology of learning as a procedure for establishing new behavior. This article illustrates a computer-controlled shaping demonstration that allows the user to specify several critical parameters of the shaping process and that then shapes the user’s mouse movements toward an arbitrary virtual (invisible) target on the computer screen. The relative effectiveness of different shaping parameters can be assessed by examining several dependent measures, such as the distance of the cursor from the target across time and the rate at which reinforcers were earned. This demonstration allows students to move beyond the notion that shaping is simply the application of the “hot-and-cold” game and to understand that there is a science underlying the art of shaping. 相似文献
130.
Overshadowed by more popular disciplines, the study of learning seems to have lost its prominent place in the undergraduate psychology curriculum. In the first part of this essay, we argue that one reason for this state of affairs is the current content of psychology of learning courses, namely, its disproportionate emphasis on facts, procedures, and everyday examples at the expense of functional and conceptual investigations. In the second part of the essay, we outline an alternative approach to the teaching of learning, one that emphasizes basic contents such as the conceptualization of learning as a biological adaptation or the study of temporal regulation, critical methodological issues such as the logic of experimental designs or the difficulties of measuring behavior, and broad epistemological problems such as the role of hypothetical constructs, the advantages of quantitative reasoning, or the origins of knowledge and its integration. By using learning as a means towards more fundamental ends, the splendor of the discipline and its prominent place in the undergraduate curriculum may be restored. 相似文献