Quantum mechanics, interference, and the brain

In this paper we discuss the use of quantum mechanics to model psychological experiments, starting by sharply contrasting the need of these models to use quantum mechanical nonlocality instead of contextuality. We argue that contextuality, in the form of quantum interference, is the only relevant quantum feature used. Nonlocality does not play a role in those models. Since contextuality is also present in classical models, we propose that classical systems be used to reproduce the quantum models used. We also discuss how classical interference in the brain may lead to contextual processes, and what neural mechanisms may account for it.     

The effects of switching between targets on the performance of a simple motor skill

Little direct evidence has emerged regarding the influence of switching between tasks on the performance of skills studied in the motor domain. The present study reported the results of two experiments that examined the effects of task switching on a simple object projection task, which presumably emphasized processes related to response planning and execution. The experimental task required participants to gently tap a knob to make it travel along two parallel rods until it reached a specified target distance. In both experiments, participants in the repeated conditions performed a single target distance while participants in the switched conditions alternated between two target distances. Results indicated that switching between targets degraded accuracy for the two short targets (30cm, Exp. 1; 20cm, Exp. 2). Results were consistent with the preservation of parameter values [Rosenbaum, D. A., Weber, R. J., Hazelett, W. M., & Hindorff, V. (1986). The parameter remapping effect in human performance. Evidence form tongue twisters and finger fumblers. Journal of Memory and Language, 25, 710-725; Sherwood, D. E. (2007). Separate movement planning and spatial assimilation effects in sequential bimanual aiming movements. Perceptual and Motor Skills, 105, 501-513] and suggested an additional role for persisting activation in accounting for spatial assimilation and magnitude effects.     

Undecidability,incompleteness and Arnol'd problems

We present some recent technical results of us on the incompleteness of classical analysis and then discuss our work on the Arnol'd decision problems for the stability of fixed points of dynamical systems.Partially supported by FAPESP and CNP_q (Brazil, Philosophy Section).     

Health care utilization by low-income clients of a community clinic: an archival study

An archival study was done of 500 medical records from a community clinic serving a low income predominantly Hispanic area of Los Angeles. The data collected included demographic characteristics and presented symptoms or reasons for visit, as well as diagnosis and treatment. The greatest number of patient visits were made for family planning services. A large porportion of the patients who received initial family planning services failed to return to the clinic for follow ups or additional supplies. A total of 208 pregnancy tests were performed in 151 of the 500 cases sampled. Of these, 152 were positive. The most frequently stated reason for requesting pediatric services was for physical exams, accounting for 30% of the visits. It should be noted that the discontinuity of care and insufficient utilization of preventive care seen in these results deserve serious attention by medical clinic administrators. The rate of patients who do not return for family planning after the initial visit is worrisome. A greater effort to attract women to family planning services at the time they request pregnancy verification could reduce the need for abortion of unwanted pregnancy. The data also indicate that changes in the wording of certain questions commonly asked of clients may be needed. This study allowed service providers to obtain important information about their performance, their needs, and the future direction that their services might take. This type of analysis is relatively low in cost and can yield important benefits, espicially if done on a periodical base in a search for policy implications.     

Histamine reverses a memory deficit induced in rats by early postnatal maternal deprivation

Early partial maternal deprivation causes long-lasting neurochemical, behavioral and brain structural effects. In rats, it causes a deficit in memory consolidation visible in adult life. Some of these deficits can be reversed by donepezil and galantamine, which suggests that they may result from an impairment of brain cholinergic transmission. One such deficit, representative of all others, is an impairment of memory consolidation, clearly observable in a one-trial inhibitory avoidance task. Recent data suggest a role of brain histaminergic systems in the regulation of behavior, particularly inhibitory avoidance learning. Here we investigate whether histamine itself, its analog SKF-91844, or various receptor-selective histamine agonists and antagonists given into the CA1 region of the hippocampus immediately post-training can affect retention of one-trial inhibitory avoidance in rats submitted to early postnatal maternal deprivation. We found that histamine, SKF-91844 and the H2 receptor agonist, dimaprit enhance consolidation on their own and reverse the consolidation deficit induced by maternal deprivation. The enhancing effect of histamine was blocked by the H2 receptor antagonist, ranitidine, but not by the H1 receptor antagonist pyrilamine or by the H3 antagonist thioperamide given into CA1 at doses known to have other behavioral actions, without altering locomotor and exploratory activity or the anxiety state of the animals. The present results suggest that the memory deficit induced by early postnatal maternal deprivation in rats may in part be due to an impairment of histamine mediated mechanisms in the CA1 region of the rat hippocampus.     

Józef Tischner’s epistemology of “political reason” and the “ethics of truth”

Studies in East European Thought - That which connects ethics and epistemology is the concept of truth. The threads concerned with the ethical and epistemological understanding of truth are...     

Should Authors be Requested to Suggest Peer Reviewers?

As part of a continuous process to explore the factors that might weaken or corrupt traditional peer review, in this paper, we query the ethics, fairness and validity of the request, by editors, of authors to suggest peer reviewers during the submission process. One of the reasons for the current crisis in science pertains to a loss in trust as a result of a flawed peer review which is by nature biased unless it is open peer review. As we indicate, the fact that some editors and journals rely on authors’ suggestions in terms of who should peer review their paper already instills a potential way to abuse the trust of the submission and publishing system. An author-suggested peer reviewer choice might also tempt authors to seek reviewers who might be more receptive or sympathetic to the authors’ message or results, and thus favor the outcome of that paper. Authors should thus not be placed in such a potentially ethically compromising situation, especially as a mandatory condition for submission. However, the fact that they do not have an opt-out choice during the submission process—especially when using an online submission system that makes such a suggestion compulsory—may constitute a violation of authors’ rights.