文明的"早生晚熟"和"晚生早熟"--中、英两国文明特征的比较与反思

本文从经济形态、政治制度、社会结构、思想观念、人格特征五个方面对中英两国文明进行观照,认为中英文明分别具有“早生晚熟”和“晚生早熟”的不同特征,而这又是与双方文明进程迥然、专制程度差异、社会结构有别以及对待传统态度不同分不开的。正是这些差别造成了中华文明从先行到落后,而英国文明虽后来反居上。因此,只有丢掉包袱。轻装上阵。中华民族才能浴火重生。     

Spermine improves recognition memory deficit in a rodent model of Huntington’s disease

Huntington’s disease (HD) is a progressive neurodegenerative disorder associated with motor and cognitive impairment. Intrastriatal administration of quinolinic acid (QA) causes neurodegeneration, glial proliferation and cognitive impairment in animals, which are similar to these seen in human HD. Since polyamines improve memory in cognitive tasks, we now tested if the post-training intrastriatal administration of spermine, an agonist of the polyamine site at the NMDA receptor, reverses the deficits in the object recognition task induced by QA. Bilateral striatal injections of QA (180 or 360 nmol/site) caused object recognition impairment, neuronal death and reactive astrogliosis. A single injection of spermine (0.1 and 1 nmol/site), 5 days after QA injection, reversed QA-induced impairment of object recognition task. Spermine (0.1 nmol/site) also inhibited QA-induced reactive astrogliosis measured by a semi-quantitative determination of GFAP immunolabelling, but did not alter neuronal death, measured by a semi-quantitative determination of fluoro-Jade C staining. These results suggest that polyamine binding sites may be considered a novel therapeutic target to prevent reactive astrogliosis and mnemonic deficits in HD.     

Rules and Self-Rules: Effects of Variation Upon Behavioral Sensitivity to Change

The Psychological Record - Four experiments compared the effects of self-rules and rules, and varied and specific schedules of reinforcement. Participants were first exposed to either several...     

Suppes Predicates for Space-Time

We formulate Suppes predicates for various kinds of space-time: classical Euclidean, Minkowski's, and that of General Relativity. Starting with topological properties, these continua are mathematically constructed with the help of a basic algebra of events; this algebra constitutes a kind of mereology, in the sense of Lesniewski. There are several alternative, possible constructions, depending, for instance, on the use of the common field of reals or of a non-Archimedian field (with infinitesimals). Our approach was inspired by the work of Whitehead (1919), though our philosophical stance is completely different from his. The structures obtained are idealized constructs underlying extant, physical space-time.     

Improving adherence to medication regimens for children with asthma and its effect on clinical outcome.

We examined the effects of a combined education and token system intervention to improve adherence to inhaled corticosteroids for an 8-year-old girl and a 10-year-old boy with asthma. Adherence was measured by an electronic chronolog monitor, and disease outcome was assessed by repeated pulmonary function testing. A withdrawal design demonstrated improved adherence and, for 1 child, an associated improvement in pulmonary function occurred. Methodological and clinical implications are discussed, including variables other than adherence that may affect disease outcome.     

Ratio estimation of distance in a large open field

Psychophysical power functions were obtained from ratio estimation of apparent distance in a large open field with two ranges of distance. The findings showed that the exponent varied with the ranges of the distances, but less steeply than previously assumed by Kunnapas (1960). Comparisons with previous results furthermore showed that the exponents obtained from ratio estimation were greater than those obtained from magnitude estimation.     

Microinfusions of flumazenil into the basolateral but not the central nucleus of the amygdala enhance memory consolidation in rats.

Extensive evidence indicates that benzodiazepine receptors in the amygdala are involved in regulating memory consolidation. Recent findings indicate that many other drugs and hormones influence memory through selective activation of the basolateral amygdala nucleus (BLA). This experiment examined whether the memory-modulatory effect of flumazenil, a benzodiazepine receptor antagonist, selectively involves the BLA. Bilateral microinfusions of flumazenil (12 nmol in 0.2 microl) into the BLA of rats administered immediately after training in an inhibitory avoidance task significantly enhanced 48-h retention performance whereas infusions into the central nucleus were ineffective. These findings indicate that the BLA is selectively involved in mediating flumazenil's influence on memory storage and are thus consistent with extensive evidence indicating that the BLA is involved in regulating memory consolidation.     

Cause as an implication

An appropriately unprejudiced logical investigation of causation as a type of implication relation is undertaken. The implication delineated is bounded syntactically. The developing argument then leads to a very natural process analysis, which demonstrably captures the established syntactical features. Next relevantly-based semantics for the resulting logical theory are adduced, and requisite adequacy results delivered. At the end of the tour, further improvements are pointed out, and the attractive terrain beyond present developments is glimpsed.This paper was presented at the 1986 Annual Conference of the Australasian Association of Logic in Auckland, 9–12 July, 1986.     

Illiteracy and brain damage. 2. Manifestations of unilateral neglect in testing "auditory comprehension" with iconographic materials

This report concerns the sentence-picture matching behavior of 100 neurologically healthy and 169 brain-damaged subjects, all of whom were unilingual adult right-handers. Within this population, 144 subjects were totally unschooled illiterates and the remaining 125 had received school education and thereafter had retained writing skills and reading habits. Brain-damaged subjects were tested less than 2 months after a first left- or right-hemisphere stroke. All subjects were administered an aphasia screening battery including, among other subtests, a set of six sentence-picture matching stimuli. For each of these six stimuli, subjects heard a sentence uttered by the examiner and were then requested to match this sentence with one of four drawings presented within a single display divided into four quadrants of equal surface. Three sentences were syntactically "simple" (noun subject + verb) and three were relatively more "complex" (noun subject + verb + one or two noun complements). Evidence of unilateral neglect was found in both left- and right-brain-damaged illiterates and literates. Moreover, the right neglect of left-brain-damaged subjects was manifest mostly when target sentences were relatively "complex" whereas the left neglect of right-brain-damaged subjects was manifest irrespective of the syntactic complexity of target sentences. Our data are interpreted as indicative of an interaction between two cognitive disorders resulting from dysfunctions of asymmetrically represented cognitive mechanisms. The implications of these findings with respect to clinical and research aphasia testing are discussed.