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排序方式: 共有161条查询结果,搜索用时 7 毫秒
151.
Roepke SK Allison M Von Känel R Mausbach BT Chattillion EA Harmell AL Patterson TL Dimsdale JE Mills PJ Ziegler MG Ancoli-Israel S Grant I 《Stress (Amsterdam, Netherlands)》2012,15(2):121-129
The stress associated with providing care for a spouse diagnosed with Alzheimer's disease can have adverse effects on cardiovascular health. One potential explanation is that chronic caregiving stress may contribute to the development of atherosclerosis. The purpose of this study was to determine whether the duration that one has provided care is associated with the degree of atherosclerotic burden, as measured by carotid artery intima-media thickness (IMT). One hundred and ten Alzheimer caregivers [mean age 74?±?8 (SD) years, 69% female] underwent in-home assessment of carotid artery IMT via B-mode ultrasonography. Data regarding medical history, blood pressure, and multiple indicators of caregiving stress were also collected. Multiple regression indicated that duration of care was positively associated with IMT measured in the internal/bifurcation segments of the carotid artery (β?=?0.202, p?=?0.044) independent of risk factors such as age, gender, body mass index, smoking history, sleep quality, hypertension status, and caregiving stressors. Duration of care was positively associated with IMT in the common carotid artery, but the relationship was not significant. These findings provide more evidence of the link between chronic caregiving stress and cardiovascular disease and indicate that enduring the experience of caregiving over a period of years might be associated with atherosclerotic burden. 相似文献
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Jonathan Grainger Mathilde Muneaux Fernand Farioli Johannes C. Ziegler 《The Quarterly Journal of Experimental Psychology Section A: Human Experimental Psychology》2005,58(6):981-998
The present study investigated the role of phonological and orthographic neighbourhood density in visual word recognition. Three mechanisms were identified that predict distinct facilitatory or inhibitory effects of each variable. The lexical competition account predicts overall inhibitory effects of neighbourhood density. The global activation (familiarity) account predicts overall facilitatory effects of neighbourhood density. Finally, the cross-code consistency account predicts an interaction, with inhibition of phonological neighbours in sparse orthographic regions and facilitation of phonological neighbours in dense orthographic regions. In Experiment 1 (lexical decision), a cross-over interaction was indeed found, supporting the prediction of the cross-code consistency account. In Experiment 2, this cross-over interaction was exaggerated by adding pseudohomo-phone stimuli (e.g., brane) among the nonword targets. Finally, in Experiment 3 (progressive demasking), we tried to shift the balance between inhibitory and facilitatory mechanisms by using a perceptual identification task. As predicted, the inhibitory effects of phonological neighbourhood were amplified, whereas the facilitatory effects disappeared. We conclude that the level of compatibility across co-activated orthographic and phonological representations is a major causal factor underlying this pattern of effects. 相似文献
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It is often assumed that graphemes are a crucial level of orthographic representation above letters. Current connectionist models of reading, however, do not address how the mapping from letters to graphemes is learned. One major challenge for computational modeling is therefore developing a model that learns this mapping and can assign the graphemes to linguistically meaningful categories such as the onset, vowel, and coda of a syllable. Here, we present a model that learns to do this in English for strings of any letter length and any number of syllables. The model is evaluated on error rates and further validated on the results of a behavioral experiment designed to examine ambiguities in the processing of graphemes. The results show that the model (a) chooses graphemes from letter strings with a high level of accuracy, even when trained on only a small portion of the English lexicon; (b) chooses a similar set of graphemes as people do in situations where different graphemes can potentially be selected; (c) predicts orthographic effects on segmentation which are found in human data; and (d) can be readily integrated into a full‐blown model of multi‐syllabic reading aloud such as CDP++ (Perry, Ziegler, & Zorzi, 2010). Altogether, these results suggest that the model provides a plausible hypothesis for the kind of computations that underlie the use of graphemes in skilled reading. 相似文献
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Peter Mitchell Gregory Currie Fenja Ziegler 《The British journal of developmental psychology》2009,27(3):513-543
We review evidence relating to children's ability to acknowledge false beliefs within a simulation account according to which our focus is set by default to the world as we know it: hence, our current beliefs assume salience over beliefs that do not fall into this category. The model proposes that the ease with which we imaginatively shift from this default depends on the salience of our current belief, relative to the salience of the belief that is being simulated. However, children do use a rule‐based approach for mentalizing in some contexts, which has the advantage of protecting them from the salience of their own belief. Rule‐based mentalizing judgements might be faster, cognitively easier and less prone to error, relative to simulation‐based judgements that are much influenced by salience. We propose that although simulation is primary, rule‐based approaches develop as a shortcut; we thus grow from individuals capable of using only simulation into individuals capable of both techniques. 相似文献
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