Effects of psychological interventions for patients with osteoarthritis: a systematic review and meta-analysis

The aim of this study was to determine the effects of psychological interventions (e.g. cognitive restructuring, relaxation) on physiological and psychological health in osteoarthritis patients. A systematic literature search was done using PubMed, Embase, PsycINFO, Web of Science, China National Knowledge Infrastructure, and Wanfang Database through November 2016. Studies were included if they used a randomized controlled trial designed to explore the effects of psychological interventions in osteoarthritis patients. Two independent authors assessed the methodological quality of the trials using criteria outlined by Jadad et al. Meta-analysis was done with the Revman5.0. Twelve randomized controlled trials, including 1307 osteoarthritis patients, met the study inclusion criteria. Meta-analysis showed that psychological interventions could reduce the levels of pain [standard mean difference (SMD) ?0.28, 95% CI ?0.48, ?0.08, P-value 0.005)] and fatigue (SMD ?0.18, 95% CI ?0.34, ?0.01, P-value 0.04). In addition, psychological interventions significantly improved osteoarthritis patients’ self-efficacy (SMD 0.58, 95% CI 0.40, 0.75, P-value 0.00) and pain coping (MD 1.64, 95% CI 0.03, 3.25, P-value 0.05). Although the effects on physical function, anxiety, depression, psychological disability were in the expected direction, they were not statistically significant. In conclusion, the role of psychological interventions in the management of osteoarthritis remains equivocal. Some encouraging results were seen with regard to pain, pain coping, self-efficacy, and fatigue. We believe that more methodologically rigorous large-scale randomized controlled trials are necessary to answer this study question.     

Serotonin transporter 5-HTTLPR genotype is associated with intrusion and avoidance symptoms of DSM-5 posttraumatic stress disorder (PTSD) in Chinese earthquake survivors

Background and Objectives: Prior studies have found that the serotonin transporter gene-linked polymorphic region (5-HTTLPR) interacts with trauma exposure to increase general risk for Posttraumatic Stress Disorder (PTSD). However, there is little knowledge about the effects of the interaction on distinct symptom clusters of PTSD. This study aimed to investigate the relation between the interaction of 5-HTTLPR and earthquake-related exposures and a contemporary phenotypic model of DSM-5 PTSD symptoms in a traumatised adult sample from China.

Design: A cross-sectional design with gene-environment interaction (G?×?E) approach was adopted. Methods: Participants were 1131 survivors who experienced 2008 Wenchuan earthquake. PTSD symptoms were assessed with the PTSD Checklist for DSM-5 (PCL-5). The 5-HTTLPR polymorphism was genotyped with capillary electrophoresis (CE) in ABI 3730xl genetic Analyzer.

Results: Although there was no significant interaction between 5-HTTLPR and traumatic exposure on total PTSD symptoms, respondents with the LL genotype of 5-HTTLPR who were highly exposed to the earthquake experienced lower intrusion and avoidance symptoms than those with the S-allele carriers.

Conclusions: The findings suggest that the 5-HTTLPR may have an important impact on the development of PTSD and add to the extant knowledge on understanding and treating of posttraumatic psychopathology.     

Atomic imaging of the interface between M23C6-type carbide and matrix in a long-term ageing polycrystalline Ni-based superalloy

Besides the well-known cube-on-cube orientation relationship (OR) between M₂₃C₆ carbide and matrix, we have determined a new OR named as the twin-related OR in a long-term ageing Ni-based superalloy on the basis of the extensive and detailed electron diffraction analyses. Furthermore, by means of atomic-resolution high angle annular dark-field imaging technique which is implemented in the aberration-corrected scanning transmission electron microscope, we elucidated the interfacial characteristics between M₂₃C₆ and matrix for above two types of ORs. Taking into account of the interfacial characteristics, we propose that the twin-related OR possesses a higher total interfacial energy. Thus, its frequency of occurrence is lower than that of the cube-on-cube OR though both ORs are usually seen in the long-term ageing samples.     

Seeing Where the Stone Is Thrown by Observing a Point-Light Thrower: Perceiving the Effect of Action Is Enabled by Information,Not Motor Experience

People are very adept at perceiving biological motion (e.g., Johansson, 1973 Johansson, G. (1973). Visual perception of biological motion and a model for its analysis. Perception & Psychophysics, 14(2), 201–211.[Crossref], [Web of Science ®] , [Google Scholar]). This ability has been an essential life skill to members of this social species. The human niche during the ice age was socially coordinated hunting for big game. Being able to judge the location targeted by the throw of a conspecific would be a valuable perceptual ability that we now study to investigate 2 competing theories of biological motion perception: Common Coding (CC; Prinz, 1997 Prinz, W. (1997). Perception and action planning. European Journal of Cognitive Psychology, 9(2), 129–154.[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]) and Kinematic Specification of Dynamics (KSD; Runeson & Frykholm, 1983 Runeson, S., & Frykholm, G. (1983). Kinematic specification of dynamics as an informational bias for person-and-action perception: Expectation, gender recognition, and deceptive intent. Journal of Experimental Psychology: General, 112, 585–615.[Crossref], [Web of Science ®] , [Google Scholar]). The 2 theories diverge in attributing perceptual ability to either motor or visual experience, respectively. To test predictions of the CC theory, we performed 3 experiments to manipulate observers' specific motor experience while they judged the targeted location of throwing by watching point-light displays. In Experiment 1, we tested whether the identity of the thrower in the display mattered. In Experiment 2, we tested whether the motor expertise of the observer mattered. In Experiment 3, we tested whether the gender/style of throwing demonstrated by the point-light thrower mattered. The combined results failed to support CC theory, suggesting that motor experience is not required for the perception of action. Because all participants judged the target location of throwing quite well, KSD theory suggests that the kinematic information available in the displays may have enabled the perception. We performed Experiment 4 to analyze the information. We found that the judgment pattern exhibited by the observers in both Experiments 1 and 2 was well predicted by the KSD theory. Thus, we concluded that the perception of biological motion is enabled by visual information and improved by visual experience.     

Intuitive Conceptions of Dead Persons' Mentality: A Cross-Cultural Replication and More

Jesse Bering (2002) investigated how American university students in an interview task conceived of dead persons' mentality immediately after death. He found that different categories of mental states or capacities were conceived differently: psychobiological and perceptual states ceased, whereas emotional, desire, and epistemic states continued. Our Study 1 was a replication of Bering's experiment in a different cultural setting, in which the subjects were Chinese undergraduate students. A similar pattern of results was found. In Study 2, instead of being asked about a dead person's various mental states immediately following the death, participants were asked to judge a dead person's mental states after the person had been dead for 2 days. The overall pattern of participants' responses was not affected by this manipulation, but they did show an increase in attributions of certain mental states to dead agnostics. In addition, a more refined breakdown of responses revealed that individuals tended to judge that, upon death, visual and auditory perception continued, whereas olfactory and gustatory sensation ceased.     

The development of social value orientation across different contexts

This study aimed to explore Chinese children's social value orientation across different ages and contexts. Revised decomposed games were used to measure the social value orientation of 9‐, 11‐, and 14‐year‐old children and college students as an adult group. About half of them were assigned to the hypothetical context of “equal payment group,” providing equal compensation for participation in the study, and the others to the “real payment group,” who got payment according to their own choices in the games. Results showed that 9‐ and 11‐year‐old children's choices differed between the two contexts: They made more prosocial choices in the hypothetical context, and more competitive choices in the “real payment” context. The 14‐year‐olds’ and adults’ choices were not significantly different in the two contexts. These results may imply that by 14 years of age, children have stable social value orientation, and their behavior reflects this value.     

Exposure to violence reduces empathetic responses to other’s pain

Past researches showed that empathy for pain not only triggers a resonance mechanism between other and self, but also is modulated by contextual factors. Using functional magnetic resonance imaging, the present study demonstrated that short-term media violence exposure reduced both pain ratings and also the activation of anterior insula and anterior mid-cingulate cortex to other’s pain. Thus, violence exposure modulated empathic responses to other’s pain based on a physiological desensitization.     

中学生知识获得过程是从情景记忆向语义记忆转化的过程

本研究探讨中学生的知识掌握过程。针对2001—2002年度上学期教学内容,对初中二年级学生的四门课程分别进行两次测验。对于每道选择题,学生首先选择正确答案,然后指出记忆的意识状态：记住的、知道的、猜测的。结果发现,学生记忆意识类型的转变(由记住向知道)取决于课程类型、保持时间和学生等级。对于不同课程,学生占优势的意识类型不同,自然学科知道的反应占优势,社会学科记住的反应占优势;优等生知道的反应多于其他学生;随着学习时间的延长,中学生的意识类型发生了由记住向知道的转变,这表明知识掌握过程中,中学生的知识表征发生了由情景记忆向语义记忆的转变。     

关于哲学的问题研究

“恰当地提出问题”对于哲学甚至比对于科学更为重要,它体现出哲学活动的特殊性质。提问开放新的视域。使我们超出习见,进入思考和对话。着重于提出问题而非构造理论,在今天可以被视为一种研究哲学的方式。当今时代给我们提出了大量需要研究的课题,也要求我们能够提出自己的问题。另一方面,20世纪哲学的自我批判,不仅使哲学的一些基本范畴被重新审视,它的探索方式乃至其功能与合法性根据也受到质询。对问题的研究已成为把握时代和探索哲学发展途径的入手处。     

国外社会惰性的理论与相关研究概述

社会惰性是团队成员在从事趋向共同目标活动中出现的努力程度和平均贡献随着群体成员增加而减少的现象。该研究从社会惰性的概念、起源和发展、理论解释,影响因素及形成过程等几个方面对国外社会惰性的研究状况进行了述评,并指出存在的问题及今后研究的方向