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141.
论马克思主义的整体性(上) 总被引:1,自引:0,他引:1
近年来,随着 "马克思主义理论"被正式确立为国家一级学科,"马克思主义学院"在全国高等院校纷纷成立,国内马克思主义研究在表面上也呈现出一派热闹非凡的景象。于是马克思主义的整体性问题被提了出来。然而,与这种表面上热闹的景象形成鲜明对照的是,真正从心灵深处认同、信仰马克思主义的人并不很多。这种悖论式的现象不能不引起我们足够的重视。对于研究马克思主义的理论工作者而言,必须对眼前令人眼花缭乱的马克思主义 "热"进行 "冷"思考,就是说,必须认真地、郑重地提出并弄清这样一个问题: 马克思主义就其本义而言,是站在大众立场、为大众立言、为 相似文献
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143.
Stress can disrupt endocrine signalling in the male reproductive axis through high concentrations of glucocorticoids, the hallmark of stress. Our previous work revealed that a stress level of exogenous glucocorticoids could induce apoptosis of rat Leydig cells, which are the primary source of testosterone. The aim of this study was to investigate whether stress can induce apoptosis in rat Leydig cells in vivo and, if so, whether the process is the result of a direct effect of glucocorticoids. In a chronically stressed rat model, serum corticosterone concentration was increased significantly whereas serum testosterone was decreased. The frequency of apoptotic Leydig cells in stressed rats was also increased. Adrenalectomised rats subjected to chronic stress showed an elevated serum testosterone, while the apoptotic frequency of Leydig cells was not increased. It was established that glucocorticoid-induced Leydig cell apoptosis is mediated by glucocorticoid receptors (GRs), which translocate from cytoplasm to nucleus. Adenovirus microRNA-induced downregulation of GR expression in vitro alleviated the corticosterone-induced increase in apoptosis of Leydig cells. These results indicate that the stress-induced increase in corticosterone secretion resulted in apoptosis in rat Leydig cells in vivo, and thereby decreased testosterone synthesis. 相似文献
144.
It is established that stress impairs spatial learning and memory via the hypothalamus-pituitary-adrenal axis response. Dopamine D1 receptors were also shown to be responsible for a stress-induced deficit of working memory. However, whether stress affects the subsequent emotional learning and memory is not elucidated yet. Here, we employed the well-established one-trial step-through task to study the effect of an acute psychological stress (induced by tail hanging for 5, 10, or 20?min) on emotional learning and memory, and the possible mechanisms as well. We demonstrated that tail hanging induced an obvious stress response. Either an acute tail-hanging stress or a single dose of intraperitoneally injected dopamine D1 receptor antagonist (SCH23390) significantly decreased the step-through latency in the one-trial step-through task. However, SCH23390 prevented the acute tail-hanging stress-induced decrease in the step-through latency. In addition, the effects of tail-hanging stress and/or SCH23390 on the changes in step-through latency were not through non-memory factors such as nociceptive perception and motor function. Our data indicate that the hyperactivation of dopamine D1 receptors mediated the stress-induced deficit of emotional learning and memory. This study may have clinical significance given that psychological stress is considered to play a role in susceptibility to some mental diseases such as depression and post-traumatic stress disorder. 相似文献
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146.
Wang RF 《Psychonomic bulletin & review》2012,19(4):575-587
The issue of reference frame is central to theories of spatial representations. Various classifications have been made for different types of reference frames, along with prototypical research paradigms to distinguish between them. This article focuses on the configuration error paradigm proposed by Wang and Spelke (Cognition 77:215-250, 2000) that has been used to examine the nature of the spatial representations underlying object localization during self-movement. Three basic models of spatial memory and spatial updating are discussed, as well as the assumptions behind the configuration error paradigm, to distinguish between static representations, such as the traditional allocentric cognitive map and the egocentric snapshots, and dynamic representations, such as the egocentric updating system. Recent experimental findings are reexamined and shown to be consistent with multiple models, among which the egocentric-updating-and-reload model with an enduring egocentric component provides the simplest interpretations. 相似文献
147.
Rivkin A Alexander RC Knighton J Hutson PH Wang XJ Snavely DB Rosah T Watt AP Reimherr FW Adler LA 《Journal of attention disorders》2012,16(8):664-674
Objective: Preclinical models, receptor localization, and genetic linkage data support the role of D4 receptors in the etiology of ADHD. This proof-of-concept study was designed to evaluate MK-0929, a selective D4 receptor antagonist as treatment for adult ADHD. Method: A randomized, double-blind, placebo-controlled, crossover study was conducted in adults with primary ADHD. The primary end point was changed from baseline in total score on the Adult ADHD Investigator Symptom Rating Scale following a 4-week treatment regimen. Additional measures included Clinical Global Impression-Severity Scale, Hospital Anxiety and Depression Scale, and Brown Attention Deficit Disorder Scale and D4 genotype analysis. Results: No statistically significant treatment differences were found between MK-0929 and placebo in any of the primary or secondary assessments. Conclusion: Results from this study suggest that blockade of the D4 receptor alone is not efficacious in the treatment of adult ADHD. 相似文献
148.
Wong YJ Nguyen CP Wang SY Chen W Steinfeldt JA Kim BS 《Cultural diversity & ethnic minority psychology》2012,18(3):258-267
The goal of this study was to identify diverse profiles of Asian American women's and men's adherence to values that are salient in Asian cultures (i.e., conformity to norms, family recognition through achievement, emotional self-control, collectivism, and humility). To this end, the authors conducted a latent profile analysis using the 5 subscales of the Asian American Values Scale-Multidimensional in a sample of 214 Asian Americans. The analysis uncovered a four-cluster solution. In general, Clusters 1 and 2 were characterized by relatively low and moderate levels of adherence to the 5 dimensions of cultural values, respectively. Cluster 3 was characterized by the highest level of adherence to the cultural value of family recognition through achievement, whereas Cluster 4 was typified by the highest levels of adherence to collectivism, emotional self-control, and humility. Clusters 3 and 4 were associated with higher levels of depressive symptoms than Cluster 1. Furthermore, Asian American women and Asian American men had lower odds of being in Cluster 4 and Cluster 3, respectively. These findings attest to the importance of identifying specific patterns of adherence to cultural values when examining the relationship between Asian Americans' cultural orientation and mental health status. 相似文献
149.
Formerly, researchers often treated adult attachment as a trait‐like construct with consistency across relationship contexts. However, recent studies have shown that people possess multiple relationship‐specific attachment representations, and inter‐correlations among them are only in a small‐to‐medium range. The aim of this study is to test whether these variable‐centred results could be replicated in China and further supplement them with a person‐centred analysis focusing on identifying prototypical patterns of multiple working models across relationships. We administrated measurements of general and four relationship‐specific (mother/father/best friend/romantic partner) working models and indicators of psychological adjustment upon 302 Chinese college students. Results from variable‐centred analysis demonstrated the cross‐relationship variability in working models. Furthermore, global indicators of psychological adjustment were better predicted by general models, while relationship‐specific indicators were better predicted by corresponding relationship‐specific models. These results largely replicate previous Western studies, supporting the existence of multiple attachment representations in China. In person‐centred analysis, a latent profile analysis identified four typical classes of working model profiles: all‐average, all‐secure, romantic‐insecure and peer‐secure. These classes differed not only in the cross‐relationship variability of their working models, but also in their levels of psychological adjustment. These interesting patterns may have theoretical implications and are worthy of further examination. 相似文献
150.
Cangbai Wang 《Journal of International Migration and Integration》2012,13(4):565-581
Immigration labor in global cities is often framed in a dichotomy of skilled and nonskilled and explained from different perspective. Based on narratives of skilled immigrants from mainland China in postcolonial Hong Kong, this study shifts the focus of attention from generalized dissimilarities between migrant groups determined by the level of skills to commonalities of experience shaped by the broader social and cultural forces of their spatial, economic and political environments. It points to the importance of ??border?? in shaping the mode of incorporation of skilled migrants to localities in global city. It shows that skilled mainland immigrants in Hong Kong are deeply embedded in an overarching xin yimin (new immigrants) discourse according to which the Hong Kong?CChina border distinguishes all mainland immigrants from Hong Kong citizens regardless of the level of skills they possess. This discourse is associated with and defined by the cultural meaning of border between Hong Kong and China produced in the colonial past and reproduced in the postcolonial present. Despite being highly educated and skilled, mainland Chinese professionals experienced countless negotiation of sameness and difference in their everyday encountering localities and making place. The stories presented here ask us to rethink the assumptions informing the analytical distinctions between skilled and non-skilled and call for ??unifying?? skilled and non-skilled migration in global cities methodologically and theoretically. 相似文献