Type D personality,but not Type A behavior pattern,is associated with coronary plaque vulnerability

Personality traits are associated with major adverse coronary events (MACE) in patients with coronary artery disease (CAD). However, the link between personality traits and intravascular morphology in CAD patients is poorly understood. This study investigated the relationship between personality traits, specifically Type A behavior pattern and Type D personality, and plaque vulnerability. After adjustment for demographic and clinical factors, multivariable regression analysis showed no association between Type A and optical coherence tomography indices. However, Type D personality was independently associated with lipid plaque, thin cap fibroatheroma (TCFA), and fibrous cap thickness. More specifically, negative affectivity of Type D was related to lipid plaque, TCFA and fibrous cap thickness, and social inhibition was associated with plaque rupture. Our results show that Type D personality was associated with plaque vulnerability, independent of clinical factors. Measurement of negative affectivity and social inhibition will increase our understanding of the progressive phase of the plaque vulnerability, which can contribute to the early identification of high risk patients and reduce the incidence of MACE.     

Effects of telephone support on exercise capacity and quality of life in patients with chronic obstructive pulmonary disease: a meta-analysis

The aim of this meta-analysis was to evaluate the effects of disease education or pulmonary rehabilitation programs assisted with telephone support on physical capacity and quality of life (QOL) in chronic obstructive pulmonary disease (COPD) patients. A systematic search of PubMed, Embase, Web of Science and The Cochrane Library was conducted until May 2017. Randomized controlled trials (RCTs) examining the effects of telephone-assisted intervention versus a control group on exercise tolerance and QOL in patients with COPD were included. Two independent authors assessed the methodological quality of the trials using the Cochrane risk of bias tool. A meta-analysis was conducted with the Revman5.3 to quantify the effects of telephone-assisted interventions on walking capacity and QOL. In total, 10 studies involving 1037 participants were included. Due to the effect of telephone-assisted interventions, statistically significant results were found on Saint-George’s Respiratory Questionnaire (SGRQ) symptom scores [standard mean difference (SMD) ?.18, 95% confidence interval (CI) ?.33, ?.03, p-value .02)], SGRQ impact scores [SMD ?.35, 95% CI ?.60, ?.10, p-value .006)], SGRQ activity scores [SMD ?.30, 95% CI ?.45, ?.15, p-value < .0001)], SGRQ total score [SMD ?.36, 95% CI ?.51, ?.21, p-value < .00001)]. The effects on 6-min walk test (6MWT) and all Chronic Respiratory Questionnaire (CRQ) subscales were not significant (p > .05) based on the insufficient evidence. In conclusion, the role of telephone-assisted interventions in the management of COPD remains equivocal. Some encouraging results were seen with regard to SGRQ symptom, SGRQ impact, SGRQ activity and SGRQ total score. We believe that more methodologically rigorous large-scale randomized controlled trials are necessary to answer this study question.     

Both Earlier Times and the Future Are “Front”: The Distinction Between Time‐ and Ego‐Reference‐Points in Mandarin Speakers’ Temporal Representation

Mandarin speakers, like most other language speakers around the world, use spatial terms to talk about time. However, the direction of their mental temporal representation along the front‐back axis remains controversial because they use the spatial term “front” to refer to both earlier times (e.g., front‐year means “the year before last”) and the future (e.g., front‐road means “prospect”). Although the linguistic distinction between time‐ and ego‐reference‐point spatiotemporal metaphors in Mandarin suggests a promising clarification of the above controversy, there is little empirical evidence verifying this distinction. In this study, Mandarin speakers’ time‐ and ego‐reference‐point temporal representations on three axes (i.e., sagittal, lateral, and vertical) were separately examined through two tasks. In a time‐reference‐point task, Mandarin speakers judged whether the time point of the second picture was earlier or later than the time point of the first picture, while in an ego‐reference‐point task, they judged whether an event or phase had happened in the past or would happen in the future. The results indicate that Mandarin speakers construe an earlier‐times‐in‐front‐of‐later‐times temporal sequence and adopt the front‐to‐the‐future orientation.     

No advantage for remembering horizontal over vertical spatial locations learned from a single viewpoint

Previous behavioral and neurophysiological research has shown better memory for horizontal than for vertical locations. In these studies, participants navigated toward these locations. In the present study we investigated whether the orientation of the spatial plane per se was responsible for this difference. We thus had participants learn locations visually from a single perspective and retrieve them from multiple viewpoints. In three experiments, participants studied colored tags on a horizontally or vertically oriented board within a virtual room and recalled these locations with different layout orientations (Exp. 1) or from different room-based perspectives (Exps. 2 and 3). All experiments revealed evidence for equal recall performance in horizontal and vertical memory. In addition, the patterns for recall from different test orientations were rather similar. Consequently, our results suggest that memory is qualitatively similar for both vertical and horizontal two-dimensional locations, given that these locations are learned from a single viewpoint. Thus, prior differences in spatial memory may have originated from the structure of the space or the fact that participants navigated through it. Additionally, the strong performance advantages for perspective shifts (Exps. 2 and 3) relative to layout rotations (Exp. 1) suggest that configurational judgments are not only based on memory of the relations between target objects, but also encompass the relations between target objects and the surrounding room—for example, in the form of a memorized view.     

“集体主义—个体主义”的差异:来自基因、大脑的证据

文章以"集体主义—个体主义"这一基本文化差异维度为基础,围绕文化、基因和大脑之间的关系,介绍了国内外最新研究进展。研究显示当人类执行各种文化任务时,那些为人类生存提供有力帮助的基因会被选择和保留下来;在自我表征,注意和知觉,决策、情绪和意向推断等心理状态或过程上的"集体主义—个体主义"文化差异都可追溯到脑功能的差异。研究者先后提出社会脑假设、文化—基因协同进化论、神经—文化交互作用模型等理论来解释基因、文化与大脑交互作用的现象。文章分析了当前研究中存在的问题,并对未来的研究进行了展望。     

Modeling of 1-3 piezoelectric composites operating in thickness-stretch vibration mode

For bulk piezoelectric ceramics plates, the fundamental thickness-stretch (TSt) waves are always coupled to the in-plane extension waves and the symmetric thickness-shear waves. The occurrence of these spurious modes in bulk piezoelectric ceramics plates is undesirable as it may interfere with the operation of transducers. 1–3 piezoelectric composites are promising candidates to suppress the spurious modes mentioned above. However, theoretical modelling of multiphase ceramic composite objects is very complex. In this study, a simple analytical TSt vibration model is constructed from three-dimensional equations of linear piezoelectricity. The mechanical damping is considered in the model by introducing a complex elastic constant. The performance of 1–3 piezoelectric composites is analysed and the electrical impedance results from theoretical and experimental analysis are compared. The results show that there is excellent agreement between the experimental electrical impedance and that obtained by the theoretical TSt vibration analysis. This indicates that 1–3 piezoelectric composites can be operated in a nearly pure TSt vibration mode near the fundamental resonance. The analytical model we present is valid for analysing 1–3 piezoelectric composites plates with large aspect ratios quickly and efficiently.     

美德伦理与规则伦理：由对立互竞到协同互补

当代西方规范伦理学在理论形态上表现为美德伦理学与规则伦理学的对立互竞。这种对立局面导源于对立双方理论动机上的共同错误:单极化企图以及对伦理学限度的认知不足。现实道德生活是多样化的,这就决定了伦理学必须采取多元化的基本概念。因此,美德伦理与规则伦理的协同互补将是规范伦理学的未来发展趋势。     

宗教本质新论

本文对现代意义上的宗教学诞生以来的各种宗教本质观作了回顾,着重探讨了对我国学界影响较大的几种宗教本质观之间的分歧及其各自的理论缺陷,提出了＂宗教是一种特殊形态的精神货币,宗教起源于人类为满足自己物质和精神需要所进行的人与异己力量之间的特殊的交换活动＂的宗教本质观与宗教起源说。并对宗教的核心─－信仰问题发表了独到的见解,认为,宗教的本质是中性的,无褒贬之分,宗教的积极意义与消极意义是宗教与政治挂钩的产物。     

Alteration of cingulate long-term plasticity and behavioral sensitization to inflammation by environmental enrichment

Exposure to an enriched environment (EE) has been shown to induce cortical plasticity. Considerable amount of research is focused on the effects of EE in the hippocampus; however, effects of EE on other brain regions and the mechanisms involved are not well known. To investigate this, we induced cortical plasticity by placing mice in an EE for one month and measured the effects of EE in the anterior cingulate cortex (ACC). Here, we show that EE enhanced the expression of the plasticity gene, egr-1, in the ACC of EE animals accompanied by enhanced cingulate long-term potentiation (LTP) and decreased cingulate long-term depression (LTD). The increased NMDA receptor NR2B/NR2A subunits current ratio is associated with the plasticity seen in the ACC while total protein levels remain unchanged. Furthermore, behavioral experiments show that these mice exposed to EE demonstrate enhanced responses to acute and long-term inflammation. Our findings suggest that exposure to EE alters physiological properties within the ACC which results in enhanced responses to inflammation.     

略论清代前期的五台山藏传佛教

清代前期,因五台山独特的地理优势,博大而悠久的佛教文化和清朝统治者的极力推崇,五台山藏传佛教渐至鼎盛。清初诸帝多次巡幸五台山;蒙藏高僧频繁朝拜;藏传佛教寺院数量、僧人人数迅猛增加;寺院管理制度日趋完善,为清初巩固民族团结和国家统一做出了重要贡献。