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Lai YT Fan HY Cherng CG Chiang CY Kao GS Yu L 《Neurobiology of learning and memory》2008,90(1):164-170
Drug-associated cues are critical in reinstating the drug taking behavior even during prolonged abstinence and thus are thought to be a key factor to induce drug craving and to cause relapse. Amygdaloid complex has been known for its physiological function in mediating emotional experience storage and emotional cues-regulated memory retrieval. This study was undertaken to examine the role of basolateral nuclei of amygdala and the intracellular signaling molecule in drug cues-elicited cocaine memory retrieval. Systemic anisomycin treatment prior to the retrieval test abolished the cues-provoked cocaine conditioned place preference (CPP) memory. Likewise, a similar blockade of cues-provoked cocaine CPP performance was achieved by infusion of anisomycin and cycloheximide into the basolateral nuclei of amygdala before the test. Intra-amygdaloid infusion of H89, a protein kinase A inhibitor, or U0126, a MEK inhibitor, did not affect retrieval of the cues-elicited cocaine CPP memory. In contrast, intra-amygdaloid infusion of NPC 15437, a PKC inhibitor, abolished the cues-elicited cocaine CPP expression, while left the memory per se intact. Intra-amygdaloid infusion of NPC 15437 did not seem to affect locomotor activity or exert observable aversive effect. Taken together, our results suggest that activation of PKC signaling pathway and probably downstream de novo protein synthesis in the basolateral nuclei of amygdala is required for the cues-elicited cocaine memory performance. However, temporary inhibition of this signaling pathway does not seem to affect cocaine CPP memory per se. 相似文献
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This paper introduces the development of the Cross‐Cultural (Chinese) Personality Assessment Inventory (CPAI) as a culturally relevant measure for personality assessment in collectivistic cultures. In addition to universal personality traits, the CPAI included indigenously derived scales that assessed the relational aspects of personality. We reported three studies that illustrated the usefulness of these indigenous scales in Chinese organizational settings. The Interpersonal Relatedness factor scales on the CPAI contributed additional value beyond scales from the universal factors of Social Potency and Dependability in profiling MBA students at senior‐level positions, in assessing hotel workers’ customer orientation, and in predicting senior executives’ leadership behaviors. 相似文献
917.
Steven D. Brown Selena Tramayne Denada Hoxha Kyle Telander Xiaoyan Fan Robert W. Lent 《Journal of Vocational Behavior》2008,72(3):298-308
This study tested Social Cognitive Career Theory’s (SCCT) academic performance model using a two-stage approach that combined meta-analytic and structural equation modeling methodologies. Unbiased correlations obtained from a previously published meta-analysis [Robbins, S. B., Lauver, K., Le, H., Davis, D., & Langley, R. (2004). Do psychosocial and study skill factors predict college outcomes? A meta-analysis. Psychological Bulletin, 130, 261–288.] were used to create the input correlation matrices for subsequent path-analytic tests of the model, using both college GPA and retention as performance criteria. Results suggested that SCCT does an adequate to excellent job of modeling academic performance and persistence, but that model fit was better when general cognitive ability versus high school GPA was used to operationalize the ability/past performance variable. Results are discussed in terms of their fit with SCCT and their practical implications. 相似文献
918.
基于计划行为理论,自编直接经验、自主学习意愿等量表,以武汉地区402名中学生为被试,系统分析直接经验对自主学习意愿的影响。结果发现:直接经验的积累可增强学习主体参与自主学习活动的意愿;直接经验对自主学习意愿的积极影响可通过行为态度等核心变量发挥间接效应实现,也可通过直接路径实现;直接经验与自主学习意愿的关系不受行为态度等核心变量调节。这些结果表明,直接经验是自主学习意愿的重要影响因子,对培养和提高学生自主学习意识具有重要价值。 相似文献
919.
采用分层抽样法在河南和云南抽取4988名高中生实施问卷调查,考察父母自主支持和教师自主支持与高中生学业、个性社会性和生涯发展的关系。结果发现:(1)学业和生涯方面,女生发展好于男生,重点学校学生发展好于普通学校学生;个性社会性方面,重点学校学生发展高于普通学校学生,高二、高三学生发展显著高于高一学生;(2)父母和教师自主支持显著正向预测高中生发展。父母自主支持对学业和个性社会性发展的影响显著高于其对生涯发展的影响;教师自主支持对学业发展影响最大,对生涯发展影响最小;(3)教师自主支持对高中生三方面发展的影响均显著大于父母自主支持;(4)父母和教师自主支持对高中生学业和生涯发展存在显著交互作用。 相似文献
920.
1557例违法犯罪者的人格研究 总被引:13,自引:0,他引:13
本研究对1557例违法犯罪者按其犯罪动机划分成利欲性、情感性、信仰性、过失性等各种类型,并应用明尼苏达多相人格测验对其人格特点进行定量的分析并引出定性的结论。 相似文献