New anticonvulsant medication uses in bipolar disorder

Therapy of bipolar disorders is a rapidly evolving field. Lithium has efficacy in classic bipolar disorders whereas divalproex sodium and carbamazepine may have broader spectrum efficacy that includes non-classic bipolar disorder. In the last 10 years, a series of anticonvulsants have been approved for marketing in the United States. Gabapentin has indirect g-aminobuytric acid-ergic actions, is generally well tolerated, and appears to have anxiolytic, analgesic, and hypnotic effects. Lamotrigine has antiglutamatergic actions and is generally well tolerated (aside from rash in 1 in 10, and serious rash in 1 in 1,000 patients). Lamotrigine is indicated for maintenance treatment in bipolar disorder. Emerging evidence suggests lamotrigine may have utility in bipolar disorder patients with depression and treatment-refractory rapid cycling, as well as analgesic effects. Topiramate and zonisamide may allow both weight loss, while topiramate may have specific efficacy in bulimia, binge eating disorder, and alcohol dependence. Two small studies found oxcarbazepine had similar efficacy to lithium and haloperidol in acute mania. Phenytoin, an older anticonvulsant, may have adjunctive acute mania efficacy. Levetiracetam, a newer anticonvulsant, may be worth exploring and has minimal drug-drug interactions. None of these newer agents has been shown effective in a large placebo controlled trial for acute mania. Although the clinical profiles of these newer anticonvulsants do not appear to overlap markedly with divalproex and carbamazepine (except perhaps for oxcarbazepine), these novel agents may still offer important new options in relieving a variety of specific target symptoms in patients with bipolar disorder.     

Rowed to recovery: the use of phonological and orthographic information in reading Chinese and English

To examine how readers of Chinese and English take advantage of orthographic and phonological features in reading, the authors investigated the effects of spelling errors on reading text in Chinese and English using the error disruption paradigm of M. Daneman and E. Reingold (1993). Skilled readers in China and the United States read passages in their native language that contained occasional spelling errors. Results showed that under some circumstances very early phonological activation can be identified in English, but no evidence for early phonology was found in Chinese. In both languages, homophone errors showed a benefit in measures of later processing, suggesting that phonology helps readers recover from the disruptive effects of errors. These results suggest that skilled readers take advantage of the special features of particular orthographies but that these orthographic effects may be most pronounced in the early stages of lexical access.     

教师心理素质的隐含研究

本研究旨在运用隐含研究方法揭示教帅应具备的心理素质及其结构。为此,本研究进行了一个预备测试与3个正式测试。研究结果表明：①创造性,责任感,教育效能感等21项特性是教师重要的心理品质;②在这些心理品质中,客观公正性、移情性、角色认同、有恒性、监控陛、责任感、非权势等11项心理品质被教师、家长、学生共同认定为最重要最基本的心理品质;③人们心目中教师心理品质由工作动因,工作行为、行为调控三个维度构成的;④综合三项测试结果,本研究认为教师心理素质是由3个维度、10项基本特性构成的。此外,文章还分析了这一结论与以前研究结果的关系及隐含研究方法对于该项研究的适用性。     

Thermal sensitivity in Tourette syndrome: preliminary report

The effects of heat on tic symptoms were studied in a sample of 78 adults with Tourette syndrome. 62 men and 16 women completed a survey concerning the type, onset, and course of their tics. 10 adult male subjects also participated in a thermal challenge during which ambient temperature was raised from 22 degrees C to 35 degrees C following a control period. Of the 78, 24% or 19 reported increased tics upon exposure to heat. Compared to the remaining 59 subjects, there were no differences in sex distribution, current age, or overall course of illness. In the thermal challenge, there was general increase in tics that was correlated with sweat rate (r = .55, p = .001). This effect was prominent in 5 of 10 subjects (rs = .29 to .63). There were no mean differences in current age, age of onset, or current severity of symptoms between the five subjects of each group. Tic symptoms in a subgroup of patients with Tourette syndrome may be sensitive to heat. Abnormal heat regulation is not a likely explanation for the observed increase in tics. The increase may be due to normal heat-loss mechanisms through dopaminergic pathways.     

声旁与整字的音段、声调关系对形声字命名的影响

采用命名任务研究了汉字形声字的声旁与整字的音段、声调关系对形声字命名反应时的影响,探讨声旁的音段、声调在汉字形声字发音中的作用。实验材料是180个汉字形声字。实验结果表明,汉字形声字的声旁与整字的音段关系对命名时间有重要影响。汉字形声字的命名存在着“规则效应”,声旁与整字音段相同时反应快,声旁与整字音段相异时反应慢。汉字形声字的命名也存在着“声调效应”。声旁与整字的声调关系对命名有重要影响。当声旁与整字声调相同时反应快,当声旁与整字声调相异时反应慢,这种效应不受字频影响。整个实验结果支持汉字认知中强的亚词汇成分自动激活的观点。     

A parallel distributed processing model of stimulus-stimulus and stimulus-response compatibility.

A parallel distributed processing (PDP) model is proposed to account for choice reaction time (RT) performance in diverse cognitive and perceptual tasks such as the Stroop task, the Simon task, the Eriksen flanker task, and the stimulus-response compatibility task that are interrelated in terms of stimulus-stimulus and stimulus-response overlap (Kornblum, 1992). In multilayered (input-intermediate-output) networks, neuron-like nodes that represent stimulus and response features are grouped into mutually inhibitory modules that represent stimulus and response dimensions. The stimulus-stimulus overlap is implemented by a convergence of two input modules onto a common intermediate module, and the stimulus-response overlap by direct pathways representing automatic priming of outputs. Mean RTs are simulated in various simple tasks and, furthermore, predictions are generated for complex tasks based on performance in simpler tasks. The match between simulated and experimental results lends strong support for our PDP model of compatibility.     

论学习的基本类型与教学设计──学习双机制理论的教学模式

本文阐述了学习的双机制理论关于学习的基本机制的观点,根据该学习理论对知识分类进行了新的划分,并分析了不同类型知识学习的信息加工过程与特点,然后提出了课堂学习与教学的“七阶段模型”及相应的教学设计。     

时间记忆层次网络模型的实验检验

实验采用分类性实验材料,使被试在对词单项目加工时形成较清晰的群集,进而形成时间组块,目的在于对时间记忆层次网络进行直接检验。其中时序判断用反时间时和正确率两种反应指标,时距估计用再现和口头估计两种方法。结果发现,时间信息记忆既存在层次网络的特征,又存在线性结构的特征。     

大学生自发反应式的互联自我与独立自我:性别差异与专业差异

Ｍａｒｋｕｓ和Ｋｉｔａｙａｍａ的自我构念理论以文化差异为基础,将人的自我观念分为独立自我和互联自我,研究假说,体育专业的学习由于有更多的社会交互作用,有助于培养学生的互联自我,文理专业的学习由于有列多的独立性,有助于培养学生的独立自我,应用２０项陈述测验对２５８名大学生的研究部分地支持了这一假设;体育专业学生有更多的具体化自我表述,文理专业学生有更多的抽象化自我表述,但是,两类学生在自我定向和社会     

阅读保持的类比结构映射效应研究

探讨文章阅读过程中类比结构映射效应与共同元素效应对阅读信息保持的迁移作用,包括两个实验,实验Ｉ探讨前阅读的源文章与目标文章在结构上与命题上的共同性对目标文章信息保持的迁移效果,结果表明,前后阅读文献的结构共同目标文章的保持有显著的促进作用,命题共同的促进作用不显著,实验２进一步探讨在源文章与目标文章结构或命题有共同性的情况下,提示与否对目标文章的信息保持效果的影响作用,结果证明,有两种情况下,提示