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41.
Involvement of hippocampal nitric oxide in spatial learning in the rat   总被引:1,自引:0,他引:1  
Nitric oxide (NO) is thought to be involved in synaptic plasticity contributing to learning and memory in several brain areas including the hippocampus. The hippocampus is believed to have a critical role in the processing of spatial information. But, data on the role of hippocampal NO in spatial learning are not consistent. So the effect of NO synthase (NOS) inhibition in the CA1 region of rat hippocampus on spatial localization was investigated in the Morris water maze (MWM). Male albino Wistar rats cannulated in their CA1 region received bilateral injections of vehicle (saline) or N(omega)-nitro-L-arginine methyl ester (L-NAME), a NOS inhibitor (50, 100 and 200 microg/0.5 microl) through the cannulae 30 min before training each day. Animals were subjected to 5 days of training in the MWM; 4 days with the invisible platform to test spatial learning and the 5th day with the visible platform to test motivation and sensorimotor coordination. The results showed dose-dependent increases (p<0.001) in escape latency, traveled distance, heading angle, and dose-dependent decreases (p<0.01) in target quadrant entries in L-NAME-received groups as compared to the control group. This impairment was reversed by co-administration of mole-equivalent doses of L-arginine (L-Arg), the NO precursor. L-Arg alone at the dose of 129.2 microg, increased heading angle (p<0.01) with no effect on other parameters. On the basis of the present data, it is concluded that processes mediated by NO synthesis in the hippocampus are essentially involved in spatial learning.  相似文献   
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43.
A comparison of scores on locus of control by two groups of children, 89 who had experienced parental physical punishment and 174 who had not experienced parental physical punishment, showed that children with experience of physical punishment scored significantly more external than children who had not experienced physical punishment. The results are discussed in relation to previous studies, and some educational implications noted.  相似文献   
44.
A comparison of scores on locus of control by three groups of children in intact families (n=676), parent loss through death (n=30), and parent loss through divorce (n = 20) showed that children from divorced families scored significantly more external than children from intact families. The results are considered in relation to previous studies and some educational implications noted.  相似文献   
45.
A comparison was made of scores on locus of control by 210 Muslim and 210 Jewish school students. These two groups were matched on sex, age, and father's education. No significant differences were found between Muslim and Jewish students. Also, frequencies of the responses to each scale item in two religious groups were compared. The results are considered in relation to previous studies and some cultural implications are addressed.  相似文献   
46.
Journal of Contemporary Psychotherapy - With an increase in depression rates and medication and psychotherapy being the primary treatment interventions for decreasing depressive symptoms, exercise...  相似文献   
47.
Journal of Rational-Emotive & Cognitive-Behavior Therapy - Depression, anxiety, stress (DAS) are triggers of tension-type headaches. The current research investigates how irrational cognitions,...  相似文献   
48.
The Internet provides a space and medium within which Muslims can shape the relationship between their religious identity and their social and political affiliations. The subjectivities of Muslims who use online space are in turn shaped by the parameters and possibilities of the Internet’s architecture and language. The multiple linkages of online spaces and the particular vernacular spoken in these spaces, a mix of written text, imagery and sound, privilege new kinds of actors and new forms of expressive and rhetorical activities. In this new space and medium, the question of imagining (or rejecting) a global Muslim identity demonstrates the subtle interplay involved in the formation of religious and media subjectivities. Developing a critical understanding of multimodal representation and communication is an essential component in studying Muslim engagement with the Internet.  相似文献   
49.
It is well established that smoking is associated with impaired mental health and sleep problems. However, the possible effects of passive smoking on cognitive and emotional characteristics have not previously been evaluated in adolescents. We investigated the association between passive smoking and cognitive and emotional function, and sleep patterns in 940 adolescent girls. The girls were divided into two groups [305 exposed subjects and 635 non-exposed subjects (the controls)]. The passive smokers had a significantly lower cognitive function and higher depression, aggression, and insomnia scores compared to the control group (P?<?0.05). No significant difference was detected with respect to day-time sleepiness and sleep apnea. Logistic regression analyses showed that the passive smokers were more likely than the controls to have cognitive impairments, depressive mood, aggressive behavior, and insomnia. Adolescent passive smokers had significant differences in their cognitive abilities and emotional function.  相似文献   
50.
Even once children can accurately remember their experiences, they nevertheless struggle to use those memories in flexible new ways—as in when drawing inferences. However, it remains an open question as to whether the developmental differences observed during both memory formation and inference itself represent a fundamental limitation on children's learning mechanisms, or rather their deployment of suboptimal strategy. Here, 7–9-year-old children (N = 154) and young adults (N = 130) first formed strong memories for initial (AB) associations and then engaged in one of three learning strategies as they viewed overlapping (BC) pairs. We found that being told to integrate—combine ABC during learning—both significantly improved children's ability to explicitly relate the indirectly associated A and C items during inference and protected the underlying pair memories from forgetting. However, this finding contrasted with implicit evidence for memory-to-memory connections: Adults and children both formed A-C links prior to any knowledge of an inference test—yet for children, such links were most apparent when they were told to simply encode BC, not integrate. Moreover, the accessibility of such implicit links differed between children and adults, with adults using them to make explicit inferences but children only doing so for well-established direct AB pairs. These results suggest that while a lack of integration strategy may explain a large share of the developmental differences in explicit inference, children and adults nevertheless differ in both the circumstances under which they connect interrelated memories and their ability to later leverage those links to inform flexible behaviours.

Research Highlights

  • Children and adults view AB and BC pairs related through a shared item, B. This provides an opportunity for learners to connect A–C in memory.
  • Being encouraged to integrate ABC during learning boosted performance on an explicit test of A–C connections (children and adults) and protected from forgetting (children).
  • Children and adults differed in when implicit A–C connections were formed—occurring primarily when told to separately encode BC (children) versus integrate (adults), respectively.
  • Adults used implicit A–C connections to facilitate explicit judgments, while children did not. Our results suggest developmental differences in the learning conditions promoting memory-to-memory connections.
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