HPV疫苗预防子宫颈癌的临床应用进展及思考

子宫颈癌是引起女性死亡的第二大癌症.研究证实人乳头瘤病毒(HPV)感染与子宫颈癌有着十分密切的关系.近年来,HPV疫苗在预防和治疗子宫颈癌方面备受关注,多种新型预防性HPV疫苗已在部分国家上市.但是HPV疫苗的研制、使用、推广仍面临许多难题,有待广大医疗工作者共同思考和解决.     

Intelligence and Prosocial Behavior: Do Smart Children Really Act Nice?

Results of previous studies of the relationship between prosocial behavior and intelligence have been inconsistent. This study attempts to distinguish the differences between several prosocial tasks, and explores the ways in which cognitive ability influences prosocial behavior. In Study One and Two, we reexamined the relationship between prosocial behavior and intelligence by employing a costly signaling theory with four games. The results revealed that the prosocial level of smarter children is higher than that of other children in more complicated tasks but not so in simple tasks. In Study Three, we tested the moderation effect of the average intelligence across classes, and the results did not show any group intelligence effect on the relationship between intelligence and prosocial behavior.     

Muscle dysmorphia: Current research and potential classification as a disorder

ObjectiveTo review the literature for scientific evidence in support of inclusion of Muscle Dysmorphia (MD) in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).DesignThe criteria proposed by Blashfield, Sprock, and Fuller (1990) were used for determining whether scientific evidence supports the introduction of MD as a new disorder into a disease classification system.MethodPeer-reviewed journal articles were identified by searching databases for articles published (in print and electronically) from 2001 to 2011.ResultsThe search identified 59 journal articles that specifically focused on MD, of which 39 were empirical journal articles. There is ample literature on MD, including a common set of diagnostic criteria and assessment instruments to measure MD. However, questions remain about the diagnostic reliability and validity, including inter-rater reliability, and whether MD represents a disorder that consists of symptoms that frequently co-occur. Also, evidence of syndrome differentiation is lacking. Only two of the five criteria proposed by Blashfield et al. have been met.ConclusionLiterature suggests that MD is associated with several indicators of clinical significance and distinctiveness. However the current review has found significant limitations and gaps in the scientific literature on MD. Possible options regarding the status of MD in the DSM-5 are proposed, including introducing MD as an example of an eating disorder not otherwise specified, retaining MD as a body dysmorphic disorder, introducing MD as a new disorder, or introducing MD as a provisional diagnosis in need of further study.     

逃生决策中的信息源直觉和分析对采纳偏向的影响

选取82名被试,探讨在突发危急事件的逃生判断和决策中人们对不同信息源的采纳偏向,同时探讨直觉和分析两种思维倾向以及直觉和分析两种决策风格对逃生判断和决策中信息源采纳的影响。结果：（1）在模拟突发危急事件的逃生判断和决策中人们对不同信息源的采纳倾向存在明显差异,来自权威、熟悉以及具有高信任度的信息源更容易被采纳;（2）直觉性思维倾向启动条件下和分析性思维倾向启动条件下的信息源采纳倾向差异不明显;（3）直觉型决策风格对信息源的采纳倾向具有明显预测性,而分析型决策风格对信息源的采纳倾向不具有明显预测性。主要结论     

Mathematics Performance of Immigrant Students Across Different Racial Groups: An Indirect Examination of the Influence of Culture and Schooling

Immigrant students are commonly assumed lower performers in US schools. Their inadequate English language skills and adaptation to the mainstream US school norms are often seen as obstacles to their successful school learning. However, whether and to what extent this assumption is sustainable for immigrant students' performances in mathematics is the question that has not been empirically explored. Proper answer to the question would help verify the popular assumption about the immigrant students and their learning in the mainstream US schools. Guided by the straight-line, segmented assimilation and cultural capital theories, this study examined this issue using US grades 4 and 8 datasets of Trend in International Mathematics and Science Study 2007 and 15-year-old dataset of Program for International Student Assessment 2009. It was found that there were substantial differences in the mathematics performances of students across different racial groups. Being immigrant students does not always mean they are lower performers than their mainstream peers. The immigrant students coming to the USA earlier did not always show worse mathematics performance over their immigrant peers who came to the USA later. These findings challenge the popular assumption that immigrant students' inadequate English language skills and adaptation to the mainstream US school norms are obstacles to their successful school learning and call for a deeper understanding about the academic performance of immigrant students in different content areas and at various stages of immigration across different racial groups.     

焦虑抑郁障碍误诊为慢性胃炎的临床分析

探讨焦虑抑郁障碍与慢性胃炎之间的关系。统计半年内在心理科门诊及住院治疗的焦虑抑郁障碍患者中曾被误诊为“慢性胃炎”的情况。结果有38例患者做胃镜检查,其中37例患者显示“浅表性胃炎”或“糜烂性胃炎”,仅1例患者胃镜报告正常。40％（15例）按“慢性胃炎”治疗能暂时减轻症状,而60％（23例）按“慢性胃炎”治疗不仅无效,症状反而加重。研究结果提示浅表性胃炎或糜烂性胃炎与人的情绪紧密相关,是焦虑抑郁障碍最常见的躯体症状之一。     

缓慢的力量——Ilizarov技术在中国微言

1950年前苏联骨科医师Ilizarov发现了牵张成骨技术,应用模仿自然的缓慢牵伸力能治愈复杂创伤骨折、骨与软组织的缺损、感染和肢体的严重畸形.这种治疗模式既不同于传统骨科手术技术,也不同于现代的创伤骨科的骨折内固定接骨(AO)技术或截骨矫形技术,这些技术的特征之一就是迅速进行骨的固定和矫正畸形.以每天1mm为特征的Ilizarov技术,不仅解决了缺损和畸形中的骨的问题,而且解决了包括血管、神经、肌肉和皮肤在内的其他软组织的生长问题,对骨科一些创伤和畸形的效果无以伦比.由于诸多原因,在我国的传播不够广泛,还需要各方努力,来一起推动该技术的发展和应用.     

缓慢的力量——Ilizarov技术在中国微言

1950年前苏联骨科医师Ilizarov发现了牵张成骨技术,应用模仿自然的缓慢牵伸力能治愈复杂创伤骨折、骨与软组织的缺损、感染和肢体的严重畸形。这种治疗模式既不同于传统骨科手术技术,也不同于现代的创伤骨科的骨折内固定接骨（AO）技术或截骨矫形技术,这些技术的特征之一就是迅速进行骨的固定和矫正畸形。以每天1mm为特征的Ilizarov技术,不仅解决了缺损和畸形中的骨的问题,而且解决了包括血管、神经、肌肉和皮肤在内的其他软组织的生长问题,对骨科一些创伤和畸形的效果无以伦比。由于诸多原因,在我国的传播不够广泛,还需要各方努力,来一起推动该技术的发展和应用。     

骨桥蛋白在心肌梗死后心力衰竭中研究进展

骨桥蛋白是一种糖基化的多功能蛋白,其具有激活细胞内信号传导、参与炎症细胞的趋化聚集、促进肿瘤的生长迁移等多种生物学功能。近年来研究表明其在心肌梗死后的炎症反应、心室重塑、细胞外基质沉积及肾素-血管紧张素-醛固酮系统的过度激活中具有重要的作用,同时其与心肌梗死后心力衰竭的严重程度及顸后亦密切相关。本文就骨桥蛋白在心肌梗死后心力衰竭中研究进展做一综述。     

Interpersonal self‐support and attentional bias on negative and positive interpersonal information

Interpersonal self‐support is an indigenous Chinese personality concept. It represents the idealized notion of the kind of personality traits that help individuals deal with interpersonal problems and develop and maintain the harmonic and appropriate social relationships required in China's collectivistic and interdependent culture. It also was assumed to be a protective personality factor with regard to mental health and was found to be negatively related to psychosomatic symptoms. In the current study, cognitive processing of interpersonal information is assumed to be an underlying mechanism that connects interpersonal self‐support with interpersonal relationships and mental health. To test this hypothesis, we conducted two experiments to investigate whether attentional bias on positive and negative interpersonal information was related to high and low interpersonal self‐support. A spatial cueing task and the emotional Stroop task were administered to two samples of high and low interpersonal self‐support Chinese undergraduate students to measure attentional bias. The results from both experiments suggested that high interpersonal self‐support students had an attentional bias toward positive interpersonal information, while low interpersonal self‐support students preferentially attended to negative interpersonal information. Study 1 indicated that attentional bias toward positive interpersonal information was easily engaged in the high interpersonal self‐support group, while attentional bias toward negative interpersonal information was both easy to engage and difficult to disengage in the low interpersonal self‐support students. These results support our hypotheses that high interpersonal self‐support people engage in positive processing of interpersonal information, whereas low interpersonal self‐support people engage in negative processing of interpersonal information. The differential balance between positive and negative processing on interpersonal information may explain why interpersonal self‐support predicts both mental health and interpersonal relationships. In addition, the relational schema may explain why interpersonal self‐support is associated with an attentional bias toward interpersonal information.