干扰素治疗慢性乙型肝炎管理策略初探

在慢性乙肝抗病毒治疗中干扰素作为一线治疗取得了一定的疗效。在治疗过程中通过选择合适的慢性乙肝患者、监测疗效、确立个体化的疗程和剂量、及时监测不良反应和恰当的处理和最大限度的提高患者的依从性可使干扰素的疗效达到最大化。     

已婚育龄少数民族妇女生殖健康现状调查研究

已婚育龄妇女的生殖健康水平影响家庭经济和后代素质,存在着民族差异.笔者调查少数民族已婚育龄妇女生殖健康现状,从社会、经济、文化等方面分析发现,民族、文化水平、经济状况、社会生殖保健服务体系是其影响因素.在生活方式、禁忌习俗与社会风尚方面,如何兴利除弊、因势利导和促进男女平等是改善各民族生殖健康状况的关键.     

辨体施膳对亚健康状态改善作用的理论机制探讨

就辨体施膳对亚健康状态改善作用从历史渊薮、理论基础、药食五味功效理论及发挥的现代作用等4个方面进行了探讨.认为对亚健康状态予以辨体施膳有其理论渊薮和基础,其概念和方法符合中医学整体观和辨证观等基本理论,是中医理、法、方、药(食)的具体体现,也是对中医药食五味功效理论的继承和发扬;辨体施膳在保证中医传统功效的同时,发挥着营养、免疫调节、调节代谢等一定的药理作用.     

药物临床试验中民事责任探析

药物临床试验是由申办者、研究者和受试者共同参与的一项实验性医疗行为.申办者与研究者应当对受试者因试验引起的不良后果承担共同民事责任.其中,因研究者的过错造成的损害后果,申办者也要基于安全保障义务承担补充责任.补充责任的承担有利于受害人的顿害能得到及时完全的赔偿.     

Can Sex‐Undifferentiated Teacher Expectations Mask an Influence of Sex Stereotypes?Alternative Forms of Sex Bias in Teacher Expectations1

This research investigated different forms of sex bias in teacher expectations relative to gymnastics performance. First, a laboratory experiment including 163 physical education teachers confirmed that stereotypes favorable to boys may influence teacher expectations in gymnastics. Next, a naturalistic study involving 15 teachers and 422 students showed that teachers expected no sex differences, even though girls performed better than boys. However, this sex bias was a result of reliance on nondiagnostic student personal characteristics favorable to boys, rather than on a stereotype per se. These results suggest that egalitarian beliefs may mask a bias in favor of a social group when group differences actually exist, and that sex‐biased teacher expectations do not inevitably involve an influence of sex stereotypes.     

Neural correlates of Traditional Chinese Medicine induced advantageous risk-taking decision making

This fMRI study examined the neural correlates of the observed improvement in advantageous risk-taking behavior, as measured by the number of adjusted pumps in the Balloon Analogue Risk Task (BART), following a 60-day course of a Traditional Chinese Medicine (TCM) recipe, specifically designed to regulate impulsiveness in order to modulate risk-taking behavior. The 14 participants recruited for this study were randomly assigned to the experimental and control groups and the TCM recipe (Panax, 520 mg; Astragalus membranaceous Bunge, 520 mg; Masnetitum, 840 mg; Ostrea gigas Thumb, 470 mg; Thinleaf Milkwort Root Radix Polygalae, 450 mg; and Os Draconis, 470 mg) was administered, as a diet supplement, to the seven participants in the experimental group. The neural activity of the two groups was monitored by a 3T MRI scanner, before and after the 60-day treatment. Associated with the improved advantageous risk-taking behavior seen in the experimental group, significantly stronger blood oxygenation level dependent (BOLD) responses were observed in the bilateral dorsolateral prefrontal cortex (DLPFC), left putamen, left thalamus, right insula, and right anterior cingulate cortex (ACC), regions which have previously been reported as being involved in risk-taking decision making. The effect of the TCM in improving advantageous risk-taking decision making appears to have been related to the enhanced efficiency of the cognitive affective system, the PFC–ACC–insula–striatum network, which functions to inhibit impulsiveness, to sensitize reward-related information, and to allow the opportunity, during risk estimation, to evaluate potential gains and losses. The findings of this study suggest that interventions acting on factors modulating risk-taking decision making could have a beneficial effect in terms of optimizing risk-taking behavior.     

奖惩线索条件下内外倾个体的自主唤醒和行为反应

将停止信号任务和金钱激励延迟任务相结合,使用16导生理记录仪记录被试的生理指标,探讨内外倾者在动机凸显情景下的生理唤醒特点以及反应调节能力。结果发现,隐含奖励和惩罚线索呈现之后,内外倾者的心率增快,内倾者的皮肤电活动显著增强。在停止信号任务中的优势反应阶段,内外倾者表现为对奖励凸显线索刺激的反应时缩短;而在非优势反应阶段,和外倾者相比较,内倾者的抑制反应错误率增高。表明内外倾者在奖惩线索条件下表现出不同的生理唤醒特点和行为反应。     

吉林、大连举办道教文化活动

我国的东北地区,是道教传播的重要区域之一.战国秦汉之际,东北地区就有方仙道的踪迹.全真道兴起后,很快就传到了东北地区.现已发现一些金末元初的全真道碑刻.人清以后,东北道教中兴.道教在东北民众的生活中打下了深深的烙印,渗透到了民间风俗之中.东北地区的年节时令和日常礼俗与道教文化有着密切的关系.     

The Challenge-and-Response Model of Normal Anxiety

This article attempts to provide a conceptual framework placing anxiety in a personal growth perspective. The authors first discuss two different theories of anxiety, review some structural models of anxiety, and stress that anxiety should be studied as a certain kind of relation or interaction between the subject and her stimuli. Then a challenge-and-response model of normal anxiety of its cognitive components is established, which sorts anxiety into heteronomous one and autonomic one, and supposes that heteronomous anxiety includes two dimensions: the fall between the level of external challenge and the level of self challenge, and the importance of the external challenge. Some related evidences for the preceding hypothesis are examined, and then compared with related models. Finally, based on the model, a valid coping strategy of anxiety was put forward, from which the mechanism of normal coping style of anxiety in daily life can be well understood.     

奖惩对注意缺陷多动障碍儿童情感决策的影响

采用简化版儿童赌博任务,其中操纵了奖励和惩罚的强度,探察两种亚型（注意缺陷型和混合型）ADHD儿童的情感决策能力,同时采集儿童在任务中的皮肤电活动以探析ADHD儿童在情感决策中的生理机制。结果发现,在不同的奖惩强度下,ADHD儿童情感决策模式不同,在即刻奖励条件下,ADHD儿童情感决策的能力明显弱于正常对照组儿童,倾向于不利选择,所产生的预测性皮电振幅也明显低于正常对照组;在即刻惩罚条件下,ADHD儿童的情感决策能力未见异常。两种亚型ADHD儿童的表现模式相似。上述结果证明,ADHD儿童仅存在对奖励的异常敏感性,并确实影响了其决策能力,而其回避惩罚的能力正常。两种亚型ADHD儿童存在的问题相似