Atypical inter‐hemispheric communication correlates with altered motor inhibition during learning of a new bimanual coordination pattern in developmental coordination disorder

Impairment of motor learning skills in developmental coordination disorder (DCD) has been reported in several studies. Some hypotheses on neural mechanisms of motor learning deficits in DCD have emerged but, to date, brain‐imaging investigations are scarce. The aim of the present study is to assess possible changes in communication between brain areas during practice of a new bimanual coordination task in teenagers with DCD (n = 10) compared to matched controls (n = 10). Accuracy, stability and number of mirror movements were computed as behavioural variables. Neural variables were assessed by electroencephalographic coherence analyses of intra‐hemispheric and inter‐hemispheric fronto‐central electrodes. In both groups, accuracy of the new coordination increased concomitantly with right intra‐hemispheric fronto‐central coherence. Compared to typically developing teenagers, DCD teenagers presented learning difficulties expressed by less stability, no stabilization of the new coordination and a greater number of mirror movements despite practice. These measures correlated with reduced inter‐hemispheric communication, even after practice of the new coordination. For the first time, these findings provide neuro‐imaging evidence of a kind of inter‐hemispheric ‘disconnection’ related to altered inhibition of mirror movements during motor learning in DCD.     

How patients’ representations of cystic fibrosis-related diabetes inform their health behaviours

Background: Although diabetes is a frequent complication of cystic fibrosis (CF), patients’ behaviours tend not to comply with best practice recommendations. Using Leventhal’s Common-Sense Model, we address this issue by exploring patients’ representations of CF-related diabetes (CFRD) to better understand the discrepancy between patients’ expected and observed health behaviours.

Methods: Semi-structured individual interviews were conducted with patients (n = 39) in six CF clinics in Quebec, Canada. These interviews were part of a larger research project on screening and management practices for CFRD.

Results: Illness representations differed between two groups of interviewed patients: (1) one group had either CF without dysglycemia or CF with impaired glucose tolerance; and (2) the other group had CFRD. Both representations were internally consistent and encompassed Leventhal’s five dimensions of illness representation: illness identity, cause, timeline, consequences and control.

Conclusions: Patients require specific information on CFRD. The screening phase could be a crucial time to help patients adjust their representations to fit the reality of CFRD.     

Effect of Transient Perturbations of Short-Term Memory on Target-Directed Blind Locomotion

It is difficult to walk without vision to a nearby destination if there is a time delay between watching the destination and walking toward it. Indeed, path deviation occurred when delays were introduced before initiating straight ahead blindfolded walking (R. A. Tyrrell, K. K., Rudolph, B. G., Eggers, &; H. W. Leibowitz, 1993 Tyrrell, R. A., Rudolph, K. K., Eggers, B. G., &; Leibowitz, H. W. (1993). Evidence for the persistence of visual guidance information. Perception &; Psychophysics, 54, 431–438.[Crossref], [PubMed] , [Google Scholar]). The questions are whether the location of a 60-s delay in the walking path and whether performing a cognitive task during the delay influence the accuracy in reaching a previously seen target while walking without vision. Thirty young adults walked blindfolded and stopped when they believed they had reached a target at 8 m. Delays were 60 s in duration, were located at 0, 4, and 7 m, and involved waiting or backward counting. Significant differences were found between 0-m and 4-m delay locations for distance to target, distance travelled and path deviation (p < .05). Significant effect of backward counting during the 60-s delay was found at the 0-m delay for distance travelled (p < .05). The interaction between retaining visual guidance information during 60 s and performing a cognitive task likely influenced target-directed blind navigation.     

Towards statistical multicriteria decision modelling: a first approach

Many real life situations result from decisions taken by a very large number of decision makers. Among them, we may cite road traffic congestion, crowding during shopping, equity market behaviour, distribution of holiday destinations, etc. Furthermore, these decisions often depend on the optimisation of several conflicting criteria. In this paper, we introduce a new multicriteria tool based on Markov chains to model and manage these macroscopic phenomena. Finally, the road traffic congestion problem will be considered to illustrate the applicability of our approach. Copyright © 2003 John Wiley & Sons, Ltd.     

The computational complexity of scenario-based agent verification and design

We first advocate that the AUML (Agent Unified Modeling Language) notation, even in its new version, is not precise enough to adequately describe protocols. This problem was long identified by Harel and we propose to follow his solution: extend sequence diagrams with a “prechart”, i.e. single out the initiation sequence of the protocol. This new notation keeps readability and intuition, but is also technically adequate and is given a formal semantics. It actually is a form of simple temporal logics, equipped with a game-based semantics, which is appropriate for modeling agent-based systems. We then go on to study its complexity. Unsurprisingly, the version with protocol roles is undecidable. The main interesting problem is to synthesize agents that follow the protocol described. Surprisingly, it is undecidable even if we remove roles, alternatives, loops, asynchronous communication, conditions, constraints, negations (already removed in AUML). The complexity of checking whether a society of agents obeys a protocol given in this trivial notation is also surprisingly high: it is PSPACE-complete, like temporal logic, while we show that this simple language is strongly less expressive than temporal logic. Notations in-between have the expected increase in expressiveness, but no increase in complexity. This justifies the use of a language including alternatives, asynchronous communication and conditions, since it increases expressiveness with no cost in complexity.     

Integrating core conflictual relationship themes in neurobiological assessment of interpersonal processes in psychotherapy

Interpersonal processes are a key target in counselling and psychotherapy. It is of paramount importance to sharpen their assessment using integrated methods. Hence, this methodological paper describes how fields of research in psychotherapy and neuroimaging can be integrated into one novel complementary neurobehavioural paradigm that can be applied to enhance our understanding of interpersonal processes in psychotherapy. To illustrate this integration, we present selected data from a pre–post pilot study where the authors assessed interpersonal processes in brief treatment for borderline personality disorder using the core conflictual relationship theme, functional magnetic resonance imaging (fMRI) and outcome questionnaires. To do so, they measured individual changes in neural activity using an fMRI task pre‐ and post‐treatment where clients gave feedback on the emotional valence of sentences extracted from their own Relationship Anecdotes Paradigm interviews mixed with neutral ones. In this paper, using data from two participants of said study, we discuss how to implement this methodology and what can be achieved in terms of results.     

Ability and Knowing How in the Situation Calculus

Most agents can acquire information about their environments as they operate. A good plan for such an agent is one that not only achieves the goal, but is also executable, i.e., ensures that the agent has enough information at every step to know what to do next. In this paper, we present a formal account of what it means for an agent to know how to execute a plan and to be able to achieve a goal. Such a theory is a prerequisite for producing specifications of planners for agents that can acquire information at run time. It is also essential to account for cooperation among agents. Our account is more general than previous proposals, correctly handles programs containing loops, and incorporates a solution to the frame problem. It can also be used to prove programs containing sensing actions correct.