Comparison between Oral and Written Spelling in Alzheimer's Disease

Written and oral spelling were compared in 33 patients with Alzheimer's disease (AD) and 25 control subjects. AD patients had poorer spelling results which were influenced by orthographic difficulty and word frequency, but not by grammatical word class. Lexical spelling was also more deteriorated than phonological spelling. Moreover, oral spelling was more impaired than written spelling in AD patients, whereas no difference was present between oral and written spelling of controls. Analysis of spelling errors showed that, for controls, errors were predominantly phonologically accurate in both spelling tasks. Significantly, AD patients produced more phonologically accurate than inaccurate errors in written spelling, whereas these errors did not differ in oral spelling. In contrast to controls who produced more constant than variable responses in oral and written spelling, AD patients made more variable responses (words correctly spelled in one task but incorrectly in the other) and they showed many instances of variable errors (different misspellings from one spelling task to the other). Two stepwise regression procedures showed that written misspellings were specifically correlated with language impairment, whereas oral spelling errors were correlated with attentional and language disorders. These results suggest that AD increases the attentional demands of oral spelling process as compared to written spelling. This dissociation argues, either for a unique Graphemic Buffer in which oral spelling requires more attentional resources than written spelling or for the hypothesis of separate buffers for oral and written spelling.     

Compassion: An east‐west comparison

Compassion is an emotion that occupies a central position in Mahāyāna Buddhist philosophy while it is often a neglected subject in contemporary western philosophy. This essay is a comparison between an Eastern view of compassion based upon Mahāyāna Buddhist perspectives and a western view of the same emotion. Certain principles found in Mahāyāna Buddhist philosophy such as the Bodhisattva Ideal, and suffering (dukkha) to name two, are explored for the information they contain about compassion. An essay by Lawrence Blum is taken as representative of a Western view (but not exclusively) and it is analyzed for its shortcomings in light of the Buddhist view. The conclusion briefly describes the value of understanding an eastern view on compassion as a means of filling the void one finds in western medical ethics discourse which focuses so heavily, and redundantly, upon issues such as patient autonomy and paternalism.     

Cartesian or condillacian linguistics?

This paper intends to deal with Condillacian Linguistics. Although the Condillacian philosophy of mind and analysis of language were the most important in the late eighteenth century, none of them is mentioned in Chomsky's work (1966, Cartesian Linguistics). It would be useful for the history of Western thought if Chomsky's monumental error were generally recognized and if Condillacian Linguistics were at last to find the place it rightly deserves. The main thesis of Condillac's linguistic ideas (language is the first step in the analysis of thought) is briefly presented with reference to its context and consequences.     

Selective delayed alternation deficits in dominantly inherited olivopontocerebellar atrophy

In order to characterize more completely the nature of the frontal lobe-type cognitive changes in patients with dominantly inherited olivopontocerebellar atrophy (OPCA) we administered two tasks sensitive to frontal system dysfunction, delayed alternation (DA) and delayed response (DR), to 12 patients from one OPCA family. Affected members from this family have previously been shown to have a marked and widespread cerebral (including frontal) cortical cholinergic reduction as severe as that observed in Alzheimer's disease. Performance on DA, but not on DR, was significantly impaired in the OPCA patients compared to that in the controls. We suggest that the DA deficits in OPCA could be a consequence of a loss of cholinergic innervation to orbitofrontal or possibly temporal cortical areas and/or damage to the integrity of the cerebello-frontal neuronal connections.     

A faith for all seasons

A FAITH FOR ALL SEASONS:ISLAM AND WESTERN MODERNITY. By Shabbir Akhtar. London: Bellew Publishing, 1990. 251pp. Hb. £25.00. ISBN 0–947792–41–4.     

Preimaginal induction of adult behaviour in insects

This review illustrates the role of preimaginal experiences in four main aspects of insect life: feeding, habitat choice, host selection, and social relationships. After an illustration of the two former aspects with examples taken from various species, special attention is paid to the two latter aspects. First, an experiment is described, which demonstrates the existence of preimaginal induction involved in host selection by the solitary parasitoid wasp Dinarmus basalis (Hymenoptera: Pteromalidae). Then, a review of preimaginal induction in ants' behaviour is presented; orientation of social behaviour, particularly altruism, is mainly determined by preimaginal imprinting. All the examples developed in this review clearly show that insects can no longer be considered as strictly, rigidly “pre-programmed” beings. Their complex behavioural development and plasticity is clearly documented.