Clinical psychologists' theory-based representations of mental disorders predict their diagnostic reasoning and memory

The theory-based model of categorization posits that concepts are represented as theories, not feature lists. Thus, it is interesting that the Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV; American Psychiatric Association, 1994) established atheoretical guidelines for mental disorder diagnosis. Five experiments investigated how clinicians handled an atheoretical nosology. Clinicians' causal theories of disorders and their responses on diagnostic and memory tasks were measured. Participants were more likely to diagnose a hypothetical patient with a disorder if that patient had causally central rather than causally peripheral symptoms according to their theory of the disorder. Their memory for causally central symptoms was also biased. Clinicians are cognitively driven to use theories despite decades of practice with the atheoretical DSM.     

Effects of acute and prolonged opiate abstinence on extinction behaviour in rats.

We examined the role of withdrawal in relapse to drug-seeking and drug-taking by testing the effects of opiate abstinence on extinction behaviour in rats trained to self-administer heroin. Male Long-Evans rats responded for IV heroin under a heterogeneous chain (VI 120 s; FR 1) schedule in which "seeking" responses preceded a "taking" response which produced a drug infusion. Responding was then measured in extinction during acute (6, 12, and 24 hr) and prolonged (3, 6, 12, and 25 day) abstinence. Sucrose consumption and somatic withdrawal were assessed at each testing period. During acute abstinence, responses on the "drug-seeking" manipulandum increased at 24 hr, whereas responses on the "drug-taking" manipulandum increased at 6 hr. Both responses were elevated during the 12-day abstinence test. Sucrose consumption was reduced and somatic withdrawal scores were increased in opiate-experienced rats at each test period. Results suggest that heroin abstinence has different effects on drug-seeking and drug-taking and that these effects do not temporally coincide with somatic measures of opioid withdrawal.     

Making a life worth living: neural correlates of well-being

Despite the vast literature that has implicated asymmetric activation of the prefrontal cortex in approach-withdrawal motivation and emotion, no published reports have directly explored the neural correlates of well-being. Eighty-four right-handed adults (ages 57-60) completed self-report measures of eudaimonic well-being, hedonic well-being, and positive affect prior to resting electroencephalography. As hypothesized, greater left than right superior frontal activation was associated with higher levels of both forms of well-being. Hemisphere-specific analyses documented the importance of goal-directed approach tendencies beyond those captured by approach-related positive affect for eudaimonic but not for hedonic well-being. Appropriately engaging sources of appetitive motivation, characteristic of higher left than right baseline levels of prefrontal activation, may encourage the experience of well-being.     

Visual search does not remain efficient when executive working memory is working

Working memory (WM) has been thought to include not only short-term memory stores but also executive processes that operate on the contents of memory. The present study examined the involvement of WM in search using a dual-task paradigm in which participants performed visual search while manipulating or simply maintaining information held in WM. Experiments 1a and 2a involved executive WM tasks that required counting backward from a target digit and sorting a string of letters alphabetically, respectively. In both experiments, the search slopes in the dual-task condition were significantly steeper than those in a search-alone condition, indicating that performing the WM manipulation tasks influenced the efficiency of visual search. In contrast, when information was simply maintained in WM (Experiments 1b and 2b), search slopes did not differ between the single- and dual-task conditions. These results suggest that WM resources related to executive functions may be required in visual search.     

Temporal organization of the brain: Neurocognitive mechanisms and clinical implications

The synchrony between the individual brain and its environment is maintained by a system of internal clocks that together reflect the temporal organization of the organism. Extending the theoretical work of Edelman and others, the temporal organization of the brain is posited as functioning through "re-entry" and "temporal tagging" and binds the wide range of possible times to a unified cognitive experience which is held in unison with the outside world. Dysfunction in this system is reflected in the temporal discord seen in cases of aging, sleep disorder, jet-lag, and shift-work, as well as in mental disorders and drug-induced changes in consciousness. The extent to which neuroendocrine structures contribute to the neurocognitive mechanisms which underlie consciousness has so far not been explored. Therefore, neuroendocrine mechanisms contributing to the temporal organization of the brain are reviewed. It is concluded that time-and its neuroendocrine correlate melatonin-is a binding principle for organizing conscious experience.     

Do women with fragile X syndrome have problems in switching attention: preliminary findings from ERP and fMRI

Fragile X syndrome (FXS) is a neurodevelopmental disorder that represents the most common known cause of developmental delay. Recent neuropsychological findings indicate that females with FXS present with a specific pattern of cognitive deficits and that these difficulties primarily involve skills requiring executive control. The present study is the first to examine the extent to which neural activity of females with FXS can be observed on a task that specifically taps two core deficits, namely switching and response inhibition. Brain activity was measured using both event-related electrical potentials (ERPs) and event-related functional MRI (fMRI) neuroimaging in separate studies using the same cognitive paradigm. Compared to controls, females with FXS were significantly slower and made more errors on trials that required an immediate response (Go) to stimulus onset but were comparable on trials that required a delayed response (Wait) to stimulus onset. At the brain level, several areas showed significantly greater activation for females with FXS compared with controls, including the cingulate cortex and left and right ventral prefrontal areas. In contrast, no areas were found to show significantly greater activation for controls compared with females with FXS.     

Ethnic and cultural variations in anger regulation and attachment patterns among Korean American and European American male batterers

This study examined relationships among ethnicity, self-construals, and 2 risk factors for marital violence (anger, insecure attachment) in Korean American and European American male batterers. Korean (vs. European) American batterers experienced more anger and controlled their anger less. Independent self-construal was positively associated with anger experience and anger control and mediated the influence of ethnicity on anger control. Korean batterers were less independent, and less independent batterers controlled their anger less. Korean batterers' attachment styles were more avoidant and less anxious. Independent and interdependent self-construals were negatively associated with anxious and avoidant attachment, respectively. Independent self-construal mediated the influence of ethnicity on avoidant attachment. Clinical severity and adherence to traditional gender roles may help explain these ethnic and cultural variations.     

Asian American multidimensional acculturation scale: development, factor analysis, reliability, and validity

This article describes the development and psychometric properties of the Asian American Multidimensional Acculturation Scale (AAMAS). The results of 3 separate studies provide strong evidence of the instrument's reliability and validity. The principles for the development of the AAMAS were orthogonality of cultural dimensions, inclusion of a pan-ethnic Asian American dimension, and ease of use across ethnic groups. Exploratory and confirmatory factor analyses indicate that within each cultural dimension (AAMAS-Culture of Origin, AAMAS-Asian American, and AAMAS-European American) there are 4 reliable acculturation domains of cultural identity, language, cultural knowledge, and food consumption. These features of the AAMAS allow for a more complex assessment of acculturation level of Asian Americans and its relationship to psychological functioning.