Uptake of Cardiac Screening and Genetic Testing Among Hypertrophic and Dilated Cardiomyopathy Families

Cardiomyopathy is a genetically and clinically heterogeneous, life threatening disease which affects people of all ages. Recent guidelines provide recommendations for cardiac screening and genetic testing in at-risk relatives, but the uptake and impact of these measures in the United States is unknown. This is a single institution retrospective study that characterizes the uptake of cardiac screening and genetic testing for relatives of a cohort of 57 probands with hypertrophic (HCM) and dilated cardiomyopathy (DCM) who underwent both clinical evaluation and genetic testing. Cardiac screening was indicated for 302 relatives. One hundred and seventy-three (57 %) completed cardiac screening. Forty of the 57 probands were mutation positive and genetic testing was indicated for 213 relatives. Eighty-four (39 %) completed genetic testing. The uptake of cardiac surveillance was greater than the uptake of genetic testing (p?<?0.0001) among relatives of mutation positive probands. Within the group of at-risk, asymptomatic relatives of probands, cardiac screening and genetic testing were positive in 25 % and 40 % of cases, respectively. These data demonstrate the important role and utility of cascade cardiac screening and genetic testing in the care of patients and families with HCM or DCM. The approach to cardiac screening and genetic testing should be family-specific and requires expertise in the genetics of cardiomyopathy.     

Framing Charity Advertising: Influences of Message Framing,Image Valence,and Temporal Framing on a Charitable Appeal1

This study examined when and how charitable advertisements could be effective in the context of child poverty. An experiment investigated the influences of message framing, image valence, and temporal framing on a charitable appeal. The results indicate that image valence enhances framing effects on advertising effectiveness of a charitable appeal when the image is congruent with the framed message, especially when the image and the message are presented negatively. A short‐term temporal frame facilitates effects of a negatively framed message with a negative pictorial presentation. Alternatively, a long‐term temporal frame increases advertising influences of a positively framed message with a positive pictorial image. Relevance for information processing of charity advertising is discussed.     

The Practicality of Ancient Virtue Ethics: Greece and China

Virtue ethics has been charged with being unable to provide solutions to practical moral issues. In response, the defenders of virtue ethics argue that normative virtue ethics exists. The debate is significant on its own, yet both sides of the controversy approach the issue from the assumption that moral philosophy has to tell us what we should do. In this essay, I would like to examine the question regarding the practicality of virtue ethics in a different way. Virtue ethics is an ancient approach shared by both ancient Greek philosophers and classic Chinese Confucians, and indeed, ancient Greeks call ethics “practical science.” How, then, do the ancients themselves view the issue of practicality? This essay shows that there is a notion of practicality which is prominent in both ancient Greek and ancient Chinese virtue ethics but is neglected in today’s ethics. According to this notion, ethics is to transform one’s life. The essay also raises a prospect of the revival of this notion.     

《周氏太极图》原图考

本文以朱震所列周敦颐<太极图>"动阳"二字的标注为突破口,对比杨甲<六经图>、<道藏·周易图>所列及朱熹改造等诸流变图,结合周敦颐<太极图易说>及<易通>的文字叙述,考证了周敦颐<太极图>的原貌.笔者认为,对<周氏太极图>的考辨,应从其"流变"人手,进而求得其图之原貌,然后方可进入考证其图之来源.文中指出:周敦颐以太极为一气,主太极有动静而生阳生阴之说,而朱熹则以太极为一理,而"理不会自动静",动静只是阴阳自身之动静,出于建立其理学系统的需要,便有意对杨甲所列<周氏太极图>进行了改造.于是,通过比较二人太极观之不同,便可从中分辨<太极图>原图与改造图之间的差别,从而分析其二人各自的理学思想.     

亲社会自主动机对青少年幸福感及亲社会行为的影响:基本心理需要满足的中介作用

本研究探讨了亲社会自主动机对青少年幸福感和亲社会行为的影响,并检验了基本心理需要满足的中介作用。研究1以293名青少年为研究对象,通过问卷法考察了亲社会自主动机、基本心理需要满足、幸福感和亲社会行为的关系;研究2以205名青少年为研究对象,通过实验法操纵亲社会自主动机（vs.受控动机）,并考察其对基本心理需要满足、幸福感和亲社会行为的影响。研究结果表明,亲社会自主动机显著正向预测青少年的幸福感和亲社会行为,并且基本心理需要满足在亲社会自主动机对幸福感和亲社会行为的预测中都起到了中介作用;相反,亲社会受控动机则不利于青少年基本心理需要的满足,进而不能有效地提升其幸福感和亲社会行为。     

Young Women’s Experience of Sexuality: A Battle of Pleasure and Sexual Purity in the Context of Malaysian Society

Little is known regarding the ways in which Malaysian women’s sexuality is constructed, and how their personal experiences, culture, religion and society influence their feeling, attitude and sexual behaviours. This study explored the sexual experiences of young adult women in the developing context of the country. A qualitative phenomenological approach was adopted. Purposive sampling was employed, and a total of 20 participants were recruited, comprised of the major ethnic groups in Malaysia. Four main themes emerged through the phenomenological analysis of the data, including: conditional pleasure; social honour and women’s purity; risk and responsibility; and transcendence of love and emotion. The findings of this study revealed that sexuality was experienced under the control of religion and society with the concern of conserving a woman’s purity and social honour; and imposing risks and responsibility on women. Despite the awareness of women’s right to experience sexual pleasure, it was commonly perceived that sexual activities beyond the social norms will result in social shaming and guilt. The authors recommend appropriate sexuality education regarding sexual assertiveness and communication, safe-sex practices, and improving sexual decision-making skills.     

Managing the interactions between multiple identities in inter-organizational collaborations: an identity work perspective

Inter-organizational collaboration (IOC) research considers the achievement of a collaborative identity as a key enabler of a successful collaboration. As a result, little has been said about the interactions between collaborative and non-collaborative identities. We build on narrative identity work and positioning theory, to explore how collaboration partners engage in identity work positioning to manage the interactions of the multiple identities emerging through the process of collaboration as they try to accomplish collaborative work. We illustrate this process through a qualitative longitudinal study of an educational partnership in Greece. Our analysis shows how IOC partners manage the interactions between collaborative and non-collaborative identities by positioning themselves, and others, in narratives of collaboration as part of their daily identity work when responding to emerging collaborative needs. Our research extends our current understanding of identity work processes in IOCs by demonstrating the paradoxical nature of the collaboration, which requires relying on both collaborative and non-collaborative identities for the successful achievement of aims. We therefore suggest that identity tensions should not be resolved but rather managed, since they enable partners to respond creatively to contextual organizational changes and make sense of the collaboration as it happens.     

Development of the ability to combine visual and acoustic information in working memory

Presentation of two kinds of materials in working memory (visual and acoustic), with the requirement to attend to one or both modalities, poses an interesting case for working memory development because competing predictions can be formulated. In two experiments, we assessed such predictions with children 7–13 years old and adults. With development, the ability to hold more information in the focus of attention could lead to an increase in the size of the trade‐off between modalities; if attention can hold A items during unimodal‐attention trials, then on average attention should hold A/2 of those same items during bimodal‐attention trials. If A increases with age, so would the dual‐task cost, A/2. The results clearly ruled out that possibility. It was the modality‐ or code‐specific components of working memory that improved with age and not the central component. We discuss various mechanisms that could have produced these results, including alternative attention‐based mechanisms. The findings point to a rich field for continued research.     

The effect of relational benefits in loyalty programmes: Evidence from Chinese milk formula customer clubs

Although the value of relational benefits has been recognised in customer relationship management, the impact of these benefits on loyalty behaviours is yet to be investigated in the context of loyalty clubs. Little is known why some loyalty programmes outperform others. By using both qualitative and quantitative research approaches, this research developed and estimated a conceptual model that describes the interaction of key relational benefits and their contributions to customer loyalty in a set of milk formula customer clubs in China. Data were collected from 300 Chinese infant milk formula buyers, including both customer club members and nonmembers. This study confirms that the customer‐confidence benefits and identity‐related benefits precede other loyalty rewards and strengthen other loyalty incentives in a loyalty programme. The economic benefits and information‐sharing benefits play a mediating role and contribute directly to customer loyalty. The findings of this research help better understand the mechanism behind loyalty behaviours in customer clubs.