自尊的遗传性:来自双生子研究的证据

自尊是个体差异的一个重要方面,迄今已有许多研究从行为遗传学角度探讨自尊个体差异的来源。通过梳理现有关于自尊的双生子研究,发现:1)自尊有中等的遗传度,其个体差异来自遗传和非共享环境;2)遗传对自尊的稳定性有较大作用;3)自尊与认知、情感的联系主要源自共同的遗传基础。总之,遗传对自尊具有重要影响。未来双生子研究可拓展到自尊波动性、内隐自尊等领域,并考虑极端人群的遗传特异性和文化对自尊遗传性的影响。     

Uptake of Cardiac Screening and Genetic Testing Among Hypertrophic and Dilated Cardiomyopathy Families

Cardiomyopathy is a genetically and clinically heterogeneous, life threatening disease which affects people of all ages. Recent guidelines provide recommendations for cardiac screening and genetic testing in at-risk relatives, but the uptake and impact of these measures in the United States is unknown. This is a single institution retrospective study that characterizes the uptake of cardiac screening and genetic testing for relatives of a cohort of 57 probands with hypertrophic (HCM) and dilated cardiomyopathy (DCM) who underwent both clinical evaluation and genetic testing. Cardiac screening was indicated for 302 relatives. One hundred and seventy-three (57 %) completed cardiac screening. Forty of the 57 probands were mutation positive and genetic testing was indicated for 213 relatives. Eighty-four (39 %) completed genetic testing. The uptake of cardiac surveillance was greater than the uptake of genetic testing (p?<?0.0001) among relatives of mutation positive probands. Within the group of at-risk, asymptomatic relatives of probands, cardiac screening and genetic testing were positive in 25 % and 40 % of cases, respectively. These data demonstrate the important role and utility of cascade cardiac screening and genetic testing in the care of patients and families with HCM or DCM. The approach to cardiac screening and genetic testing should be family-specific and requires expertise in the genetics of cardiomyopathy.     

Ethical Considerations for Volunteer Recruitment of Visual Prosthesis Trials

With the development of visual prostheses research from the engineering phase to clinical trials, volunteer recruitment for the early visual prosthesis trials needs to be carefully considered. In this article, we mainly discuss several issues related to volunteer recruitment that had posed serious challenges to the visual prosthesis trials, such as low rates of participants, high expectations and underlying motivations to participate in the visual prosthesis trials as well as the importance of informed consent. When recruiting volunteers for visual prosthesis implants, it is critical that the visual prosthesis researchers should not only take into account the patient’s expectations and motivations, but also make the patients fully aware of the possible benefits and risks involved with their participation, and help patients establish realistic expectations for the early phase of visual prosthesis implantation. Based on these considerations to the challenges, eligible volunteers may be recruited in the preliminary stages of visual prosthesis trials.     

汉字形码和音码的整体性对部件识别的影响

本实验从分析汉字整体知觉的具体表现形式入手,通过三个实验探讨字的整体知觉对部件知觉的影响。实验一以分解方式为变量,考查字形整体知觉对部件识别的影响,发现识别不同结构的字的部件之活动受知觉分解路线(如顺读或逆读)的影响。作者认为这种分解方式效应很可能跟部位有关。实验二证实了这一分析,并进而认为部位效应又跟部位与字形整体知觉的紧密程度有关。实验三以语音码为变量,发现成字部件的字音与整体字语音一致者(形声字),其分解知觉成绩比不一致者(非形声字)有明显的优势。这意味着,整体字音知觉的单一性对部件知觉的作用。最后,本研究还考查了部件识别法的有效性,并认为在研究知觉的整体与部分关系问题时,该法不失为一种新的实验范型。     

Managerial Stress in Greater China: The Direct and Moderator Effects of Coping Strategies and Work Locus of Control

La présente étude examine les effets directs et modérateurs des stratégies de défense (contrôle et support) et de la perception de contrôle au travail (extérieure) sur des relations stresseur-tension entre des gestionnaires de la grande Chine (la République populaire de Chine, Hong Kong, et Taiwan). Les données ont été recueillies, via un questionnaire autoadministré, auprès de 876 gestionnaires soit 249 (164 hommes, 85 femmes) en République populaire de Chine, 280 à Hong Kong (159 hommes, 120 femmes, 1 non classifié), et 347 (191 hommes, 151 femmes, 5 non classifiés) au Taiwan. Des effets directs et modérateurs pour les stratégies de défense et pour la perception de contrôle ont été démontrés pour quelques relations stresseur-tension dans les divers échantillons étudiés.
The present study aims at examining the direct and moderator effects of coping strategies (control and support coping) and work locus of control (externality) on the stressor-strain relationships among managers in Greater China (the People's Republic of China [PRC], Hong Kong, and Taiwan). A self-administered survey method was employed to collect data from 249 (164 male, 85 female) managers in the PRC, 280 (159 male, 120 female, 1 unclassified) managers in Hong Kong, and 347 (191 male, 151 female, 5 unclassified) managers in Taiwan. The direct and moderator effects of control coping, support coping, and work locus of control on some stressor-strain relationships were demonstrated in the studied samples.     

学习不良儿童社会信息加工的特点

设置儿童与同伴、成人相互作用的三类情景,每类情景又分为模糊情景和清晰情景两种情况,通过对51名小学生进行结构性访谈,比较了学习不良儿童与一般儿童在信息加工各阶段的差异。结果发现,无论是模糊情景还是意义清晰情景,学习不良儿童和一般儿童在对权威社会情景进行编码时存在显著差异,学习不良儿童的编码准确性和全面性显著低于一般儿童;在模糊同伴情景下,学习不良儿童的反应数量显著多于一般儿童,其消极或侵犯性的反应也多于一般儿童。     

基因工程药物发展的历史及启示

基因工程诞生20余年,运用于医药行业,研制和开发工程药物,已取得长足进展,迄今为止,已有近100个基因工程新药上市,并有数百种正在研制和开发中,可以预计,基因工程药物的发展具有无比强大的生命力。就基因工程药物发展史进行概述,会从中得到许多启示。     

大学生价值取向的特点及其与家庭因素的相关研究

采用问卷法对大学生的价值取向及其与家庭因素的关系进行了研究。发现当代大学生的价值取向呈现出注重平等、公正,男生比女生更看重个人发展的特点;相对来说,不重视个人需要的表达,而对权威的服从表现了相当的重视;大学生价值取向的特点状况与家庭因素,尤其与父母的养育风格、个体认同的影响源密切相关。     

待岗人员的应付方式、控制感特点及其关系研究

对待岗人员的应付方式和控制感进行调查发现：（1）待岗人员对待压力的应付方式依次为退避、合理化、求助、自责、发泄。女性更多地采用这五种应付方式,年龄偏大组更倾向于选择合理化和退避,30岁是应付方式发展的转折时期;（2）待岗人员的控制感由高至低依次为环境变化、人际关系、情绪情感和生活方面的控制感。女性更能控制情绪情感;（3）在待岗人员应付待岗后各种压力的情境下,可将退避归为积极的应付方式,将自责、求助、发泄归为消极的应付方式。