Use of Genetic Tests among Neurologists and Psychiatrists: Knowledge,Attitudes, Behaviors,and Needs for Training

This study explores neurologists’ and psychiatrists’ knowledge, attitudes, and practices concerning genetic tests. Psychiatrists (n?=?5,316) and neurologists (n?=?2,167) on the American Medical Association master list who had agreed to receive surveys were sent an email link to a survey about their attitudes and practices regarding genetic testing; 372 psychiatrists and 163 neurologists responded. A higher proportion of neurologists (74 %) than psychiatrists (14 %) who responded to the survey had ordered genetic testing in the past 6 months. Overall, most respondents thought that genetic tests should be performed more frequently, but almost half believed genetic tests could harm patients psychologically and considered legal protections inadequate. Almost half of neurologists (49 %) and over 75 % of psychiatrists did not have a genetics professional to whom to refer patients; those who had ordered genetic tests were more likely than those who did not do so to have access to a genetic counselor. Of respondents, 10 % had received patient requests not to document genetic information and 15 % had received inquiries about direct-to-consumer genetic testing. Neurologists reported themselves to be relatively more experienced and knowledgeable about genetics than psychiatrists. These data, the first to examine several important issues concerning knowledge, attitudes and behaviors of neurologists and psychiatrists regarding genetic tests, have important implications for future practice, research, and education.     

A virtual psychiatric ward for orientating patients admitted for the first time

Misconceptions about psychiatric wards frequently cause newly admitted mental patients to stay away from these wards despite their need for treatment. Although ward orientation is typically conducted by nurses in an attempt to help patients to adapt to the new environment, it is considered time-consuming, and the method of orientation and the explanations given may vary among different nurses. This situation calls for a more effective and standardized approach to orientating mental patients on their first admission. To this end, a computer-based interactive virtual environment was developed based on a real psychiatric ward by using virtual reality (VR) technologies. It enables the patient to navigate around to gain understanding about the ward through a virtual guided tour. The effectiveness of this VR orientation approach was investigated by a randomized controlled trial with consecutive sampling. Fifty-four Chinese participants were randomly assigned to undergo ward orientation by either using the VR-based approach or reading text-based electronic information sheets about the ward with a computer. Subjective and objective measures were obtained respectively using the Chinese version of the State-Trait Anxiety Inventory questionnaire and the heart-rate variability measurement before and after the intervention. In addition, a test on the level of understanding about the ward was administered at the end of the session. The results showed that the VR orientation approach is helpful in reducing patients' anxiety while also improving their level of understanding about the ward.     

Holistic versus analytic processing: Evidence for a different approach to processing of Chinese at the word and character levels in Chinese children

Among 30 Hong Kong Chinese fourth graders, sensitivities to character and word constructions were examined in judgment tasks at each level. There were three conditions across both tasks: the real condition, consisting of either actual two-character compound Chinese words or real Chinese compound characters; the reversed condition, with either the order of the two morphemes in the word or the order of the semantic and phonetic radicals in the character reversed; and the random condition, with either two morphemes randomly combined to create arbitrary nonwords or a semantic radical and a phonetic radical randomly combined using correct orthographic rules to create noncharacters. On the word level, children performed worst in the reversed condition and best with real words, whereas on the character level, children performed worst in the random condition and best in the reversed condition. Findings imply a holistic tendency toward word-level processing and an analytic approach to character-level processing in these Chinese children.     

Early maturation of frequency-following responses to voice pitch in infants with normal hearing

Neural plasticity of pitch processing mechanisms at the human brainstem, as reflected by the scalp-recorded frequency-following response (FFR) to voice pitch, has been reported for normal-hearing adults. Characteristics and maturation of such a response during the first year of life have remained unclear. The purpose of this study was to examine the characteristics of FFR to voice pitch in normal-hearing infants and to make a direct comparison with adults using the same stimulus and recording parameters. 9 infants and 9 adults were recruited. A Chinese monosyllable that mimics the English vowel /i/ with a rising pitch was used to elicit the FFR to voice pitch. The results demonstrated that infant FFRs showed slightly larger Pitch Strength but comparable Frequency Error, Slope Error, and Tracking Accuracy to those obtained from adults. Early maturation of FFRs was also observed in the infants starting from 1 to 3 mo. of age.     

Two models of unawareness: comparing the object-based and the subjective-state-space approaches

This article attempts to motivate a new approach to anti-realism (or nominalism) in the philosophy of mathematics. I will explore the strongest challenges to anti-realism, based on sympathetic interpretations of our intuitions that appear to support realism. I will argue that the current anti-realistic philosophies have not yet met these challenges, and that is why they cannot convince realists. Then, I will introduce a research project for a new, truly naturalistic, and completely scientific approach to philosophy of mathematics. It belongs to anti-realism, but can meet those challenges and can perhaps convince some realists, at least those who are also naturalists.     

The Effect of Highly Concentrated Oxygen Administration on Cerebral Activation Levels and Lateralization in Visuospatial Tasks

This study investigated what effect a 30% oxygen administration had on visuospatial cognitive performance and cerebral activation and lateralization using fMRI. Eight college students were selected as the subjects for this study. An oxygen dispenser that provided 21% and 30% oxygen at a constant rate of 8L/min was developed. In order to measure the performance level of visuospatial cognition, two psychological tests were also developed. The experiment consisted of two runs, one for a visuospatial cognition task with normal air (21% oxygen) and the other for a visuospatial cognition task with hyperoxic air (30% oxygen). Functional brain images were taken with a 3T MRI using the single-shot EPI method. The results of the visuospatial behavioral analysis reveal that accuracy rates were enhanced with 30% oxygen administration when compared to 21% oxygen. There were more activations observed at the bilateral occipital, parietal, and frontal lobes with 30% oxygen administration. However, decreased cerebrum lateralization was observed with 30% oxygen administration in the same regions compared with 21% oxygen administration. Thus, it is concluded that the positive effect on the visuospatial cognitive performance level by the highly concentrated oxygen administration resulted from an increase of cerebrum activation and a decrease of cerebrum lateralization.     

Detecting Suicide Risk Among College Students: A Test of the Predictive Validity of the Modified Emotional Stroop Task

Detecting suicide risk among nonclinical populations is challenging due to low base rates and the help‐negation tendency of at‐risk individuals. The current longitudinal study investigated the predictive validity of the modified emotional Stroop task (EST) by conducting a follow‐up study of 197 students who participated in a study by Chung and Jeglic (2016). The EST latencies for suicide‐related cues and past suicidal behaviors were the only significant predictors of suicide risk. The findings of this study provide preliminary support for the use of the EST as part of a suicide risk screening battery that could add to the detection of suicide risk.