时序信息提取机制的探索

对时序信息加工的经典研究是采用新近性判断范型,结果发现其提取机制是以新近性为基础的逆向串行搜索过程。本研究采用新近性判断范型和早远性判断范型对时序信息的提取机制进行了深入的考察,结果表明：（ｌ）提取时序信息既存在逆向串行搜索,又存在顺向串行搜索;（２）早远性判断和新近性判断任务对不同部分时序信息恢复的效应不同,其中早远性判断易化早远部分,新近性判断易化新近部分──表现为对相应部分辨别力的提高和正确反应潜伏期的缩短;（３）在不同的时序信息提取任务中,被试会根据具体条件进行反转反应。     

在自然光照射下工作面照度与照度分布对学前儿童操作技能影响的研究

通过在自然光照射下,测定不同年龄的学前儿童在不同的工作面照度与不同的工作面照度分布情况下,在规定时间内从红色、黄色、绿色３种球状ＰＶＣ塑料颗粒的混合物中分拣出绿色颗粒的多少,来探讨电磁波谱中的可见光部分对学前儿童操作技能的影响。为创造适宜学前儿童进行操作训练的健康环境提供依据。     

侧脑室注射东莨菪碱对条件反射及对海马神经元自发放电的影响

本工作采用食物性运动,条件反射方法和慢性微电极记录技术。条件反射实验在9只兔上进行,海马自发放电的实验在22只兔上进行。在9次实验中,30μg的东莨菪碱注入一侧脑室后,条件反射均受到抑制,而吃食则不受影响。注射剂量为45μg时,注射后3—5分,条件反射完全消失,而吃食行为在了次实验中不受影响,在2次实验中稍有减弱,注射后20分钟左右条件反射开始恢复;侧脑室注射40μg的东莨菪碱后,海马神经元的自发活动无明显改变。文中并对抗胆碱药作用于海马抑制条件反射的可能方式进行了讨论。     

Pharmacological dissociation of memory: anisomycin, a protein synthesis inhibitor, and leupeptin, a protease inhibitor, block different learning tasks

Inhibition of protein synthesis by anisomycin for a short duration impairs memory of a one-trial inhibitory avoidance task in rats. Memory of escape conditioning involving eight trials is disrupted only if the duration of protein synthesis is prolonged by repeated injections. In marked contrast, olfactory memory of rats trained on two odor discriminations is not affected by anisomycin even if the duration of inhibition is prolonged and the number of trials is reduced to a minimum. In previous work, leupeptin, a thiol proteinase inhibitor, was shown to impair olfactory discrimination learning, but left inhibitory and avoidance conditioning intact. Together, these results provide a pharmacological double dissociation of memory, and suggest that the same chemistries, or mixtures of chemistries, may not be involved in all types of memory.     

Exploration and avoidance in rats with lesions in amygdala and piriform cortex

Lesions localized to specific areas of the amygdala and overlying cortex in rats produced differential effects in several behavioral tasks. Three different types of lesions were tested: central, basolateral, and cortex lateral to the amygdala. Lesions restricted to the central nucleus produced increased activity on all parameters studied in an open-field test, but the other two groups were not changed. In one-way active avoidance all three groups with lesions showed deficits. The most pronounced change was observed in the central group. All groups showed the same degree of retention loss, but in forced extinction of one-way active avoidance after retraining, the cortical and basolateral groups were most defective. A fear-reduction hypothesis is proposed for the central lesion. The basolateral and cortical areas may be more specifically involved in passive avoidance behavior.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Why child neuropsychiatry?]

The author gives a brief survey of the development of Child-Neuropsychiatry in the G.D.R. and subsequently gives reasons for the decision in favor of the unity of neurology and psychiatry as applied to children and juveniles, which is in contrast to developments in other countries. In addition to hygienic, economic, organizational, and medical considerations, this decision was also determined by the fact that a Child-Neuropsychiatrist must, in his practical work as a subspecialist, be able to head a multiprofessional team and, thus, help assure optimum development of a child's personality.     

Category width and differentiation in semantic categories

The hypothesis that the judgemental categorizing behaviour measured by Pettigrew's Category-Width scale is linked to semantic categorization is investigated. Individual differences in broad vs. narrow categorizing behaviour measured by the C-W scale are reconceptualized within the framework of Rosch's (1977) theory of human categorization. Two extreme groups on the C-W scale, broad categorizers and narrow categorizers, were selected as subjects. One experiment employed a short-term release-from-proactive-inhibition paradigm. The amount of discrepancy in recall between the preshift and the shift trials was used as an index to perceived semantic distance. The result showed that narrow categorizers perceived the same fuzzy items in a semantic category as less similar to the good exemplars of that category than broad categorizers did. In a further experiment using a semantic-categorization technique, narrow categorizers judged the same fuzzy items as category members less frequently than broad categorizers did, indicating that narrow categorizers possess more differentiated semantic categories than do broad categorizers. These findings are seen as an extension of the differential categorizing behaviour on artificial categories in the C-W scale to semantic categorization for which there is a pre-existing system.