组织微阵列方法检测CD105、VEGF-C在肝癌组织中的表达

新生血管生成不仅为肿瘤组织提供营养支持,而且是肿瘤细胞进入循环系统的途径.CD105仅在激活的上皮细胞表达;VEGF-C为重要的血管生成因子之一,但二者与肝癌转移是否存在关联尚不明晰.探讨CD105及VEGF-C表达与肝癌肝内转移的关联.构建承载37例肝癌及癌旁组织的组织微阵列,免疫组织化学方法检测CD105及VEGF-C的表达.存在肝内转移的肝癌组织MVD-CD105均值为28.4±19.4,而无肝内转移的肝癌组织MVD-CD105均值为5.4±5.2,差异显著(P＜0.01);VEGF-C在存在肝内转移的肝癌组织表达率为46.15%(6/14),无肝内转移的肝癌组织中表达率为41.67%(10/24),二者无显著差异.MVD-CD105分值与肝癌肝内转移密切相关;血管生成可能在肝癌肝内转移过程中起重要作用.     

Comparing Chinese youth with American youth on adjustment: An illustration of measurement issues in cross-cultural research

In this article, we used results from two studies to show the need to go beyond linguistic equivalence to establish construct validity and measurement invariance in cross-cultural research. Study 1 examined Rosenberg Self-Esteem (RSE; 10 items) data from 156 Mainland Chinese youth (M = 13.8 years, SD = .53) and 213 Chinese-American youth (M = 13.6 years, SD = 2.1) from high socioeconomic status (SES) families. The Chinese translation of the RSE has been widely used. Study 2 included 1060 Mainland Chinese youth (M = 15.6 years, SD = 2.3) and 412 racially diverse American youth (M = 16.0, SD = 2.9) from all SES backgrounds. Data were collected with the third and newest edition of the Behavioural Assessment System for Children-Self Report of Personality (BASC-3-SRP; 189 items). We translated and back-translated the BASC-3-SRP between English and Chinese to establish linguistic equivalence. All participants were females. Study 1 showed that the RSE had acceptable internal consistency but lacked construct validity. Study 2 showed that the original and the translated BASC-3-SRP had good internal consistency and construct validity, but nine of its 16 subscales lacked measurement invariance. These results highlight measurement issues facing international and cross-cultural research.     

From Implicit Theories to Creative Achievements: The Mediating Role of Creativity Motivation in the Relationship between Stereotypes,Growth Mindset,and Creative Achievement

Research has demonstrated that implicit theories of creativity are crucial in shaping an individual’s behavior and real‐life decisions toward being creative. The present study proposed and examined the underlying mechanisms of how two kinds of implicit theories—the growth mindset of the creative self and the stereotype of creative others—are associated with creative achievements through the mediating role of creativity motivation. Participants were 606 undergraduate students who were enrolled in an education major in two universities in China. Overall, the study found that Chinese students held a positive image toward a creative student, regarding him or her as highly competent, warm, and popular. Student perceptions of a creative other were positively related to their growth mindset of creativity. Moreover, results verified both the mediating role of creativity motivation on growth mindset, as well as the effect of positive stereotyping of the creative other on students’ creative achievement. These findings point to promising creativity motivation strategies including the cultivation of a malleable view of creativity and of creative role models, that may, in turn, promote creative achievement by encouraging students to do, learn, and accomplish new things.     

Examining the Potential Mental Health Costs of Defending Victims of Bullying: a Longitudinal Analysis

Research on Child and Adolescent Psychopathology - It has been speculated that defending victims of bullying is stressful for youth, and may contribute to poor mental health among those who...     

Changing the Criminal Justice System Response to Sexual Assault: An Empirical Study of a Participatory Action Research Project

In jurisdictions throughout the United States, thousands of sexual assault kits (SAKs; also known as a “rape kits”) have not been submitted by the police for forensic DNA testing. DNA evidence may be helpful to sexual assault investigations and prosecutions by identifying perpetrators, revealing serial offenders through DNA matches across cases, and exonerating those who have been wrongly accused. This paper describes a longitudinal action research project conducted in Detroit, Michigan after that city discovered approximately 11,000 untested sexual assault kits in a police department storage facility. We conducted a root cause analysis to examine individual, organizational, community, and societal factors that contributed to the development of the rape kit backlog in Detroit. Based on those findings, we implemented and evaluated structural changes to increase staffing, promote kit testing, and retrain police and prosecutors so that cases could be reopened for investigation and prosecution. As we conducted this work, we also studied how this action research project impacted the Detroit criminal justice system. Participating in this project changed stakeholders’ attitudes about the utility of research to address community problems, the usefulness of DNA evidence in sexual assault cases, and the impact of trauma on survivors. The results led to new protocols for SAK testing and police investigations, and new state legislation mandating SAK forensic DNA testing.     

Association between shame aversion and ruminative retribution: Evidence for moderation by externalization of blame and control

Motivation and Emotion - Shame aversion has been theorized to motivate aggression against the self or others as means of down-regulating shame. Additionally, the direction of aggression may depend...     

被动性社交网站使用与青少年体像烦恼的关系:体像比较和体像自我差异的中介作用

为探讨被动性社交网站使用和青少年体像烦恼的关系,基于社会比较理论和自我差异理论,采用被动性社交网站使用问卷、社交网站体像比较量表、理想体像问卷和体像烦恼量表,对789名初、高中生进行调查。结果表明：（1）被动性社交网站使用对青少年体像烦恼具有显著的正向预测作用;（2）体像比较和体像自我差异能在被动性社交网站使用和体像烦恼的关系中起中介作用;（3）在被动性社交网站使用与体像烦恼的关系中,女生的体像比较和体像自我差异起并行中介作用,而对男生而言,体像比较和体像自我差异起链式中介作用。研究结果表明被动性社交网站使用不仅能直接影响青少年的体像烦恼,还可通过体像比较和体像自我差异的间接作用对青少年体像烦恼产生影响,且中介路径存在性别差异。     

中国人社会善念的心理结构

为探究中国人社会善念的心理结构, 研究采用人格词汇法, 在开放调查收集的词汇中选取代表社会善念的心理词语, 确立了社会善念词库。通过两次探索性因素分析和验证性因素分析, 得到包含18个人格特质词的社会善念词汇评定量表和包含17项描述的社会善念自陈量表。研究表明, 中国人的社会善念是一种具有二阶四因素结构的人际特质, 二阶是指宜人特质和外倾特质, 四因素分别是善良尊重、谦和恭逊、包容理解和积极开放。     

价值观的稳定性与可变性

价值观是人们区分好坏、善恶、美丑、损益、是非的信念系统,通常是充满情感的。价值观具有稳定性与可变性的特点。价值观的稳定性表现为:基本价值观具有跨时间的稳定性和跨情境的一致性; 特别是保护性价值观和人生价值观具有较强的稳定性。个人的发展、经历重大事件以及实验干预可导致价值观的改变,可变性主要表现为价值观的重要性发生变化。从我国的实际出发,探讨个人的核心价值观问题、以及价值观研究中国化、价值观研究对价值观教育的启示,乃是我们今后研究的关注点。     

SC-IAT范式下中学生良心的内隐性

目的:研究探讨了单类内隐联想测验(Single Category Implicit Association Test,SC-IAT)测量中学生良心的可行性,并分析内隐良心和外显良心的关系。方法:采用E-prime3.0软件编制SC-IAT良心测量程序,测量了中学生内隐良心; 采用青少年良心问卷测量了中学生的外显良心,并运用相关技术分析两者之间的关系。结果:SC-IAT实验中,中学生良心的内隐效应显著,且不存在性别、独生与否、学段、家庭结构、家庭所在地等人口统计学指标上的显著差异; 内隐良心与外显良心之间的相关不显著。结论:(1)中学生良心存在积极内隐效应;(2)外显良心和内隐良心相互分离,是两个不同的建构。