Parallel associative processing in the dorsal striatum: segregation of stimulus-response and cognitive control subregions

Although evidence suggests that the dorsal striatum contributes to multiple learning and memory functions, there nevertheless remains considerable disagreement on the specific associative roles of different neuroanatomical subregions. We review evidence indicating that the dorsolateral striatum (DLS) is a substrate for stimulus–response habit formation – incremental strengthening of simple S–R bonds – via input from sensorimotor neocortex while the dorsomedial striatum (DMS) contributes to behavioral flexibility – the cognitive control of behavior – via prefrontal and limbic circuits engaged in relational and spatial information processing. The parallel circuits through dorsal striatum interact with incentive/affective motivational processing in the ventral striatum and portions of the prefrontal cortex leading to overt responding under specific testing conditions. Converging evidence obtained through a detailed task analysis and neurobehavioral assessment is beginning to illuminate striatal subregional interactions and relations to the rest of the mammalian brain.     

Are children's faces really more appealing than those of adults? Testing the baby schema hypothesis beyond infancy

This study examined adults’ evaluations of likeability and attractiveness of children’s faces from infancy to early childhood. We tested whether Lorenz’s baby schema hypothesis (Zeitschrift für Tierpsychologie (1943), Vol. 5, pp. 235-409) is applicable not only to infant faces but also to faces of children at older ages. Adult participants were asked to evaluate children’s faces from early infancy to 6 years of age in terms of their likeability and attractiveness, and these judgments were compared with those of adult faces. It was revealed that adults judged faces of younger children as more likeable and attractive than faces of older children, which were in turn judged as more likeable and attractive than adult faces. However, after approximately 4.5 years of age, the baby schema no longer affected adults’ judgments of children’s facial likeability and attractiveness. These findings suggest that the baby schema affects adults’ judgments of not only infant faces but also young children’s faces. This influence beyond infancy is likely due to the fact that facial cranial growth is gradual during early childhood and certain crucial infantile facial cues remain readily available during this period. Future studies need to identify these specific cues to better understand why adults generally show positive responses to infantile faces and how such positive responses influence the establishment and maintenance of social relationships between young children and adults.     

A twin study of spatial and non-spatial delayed response performance in middle age

Delayed alternation and object alternation are classic spatial and non-spatial delayed response tasks. We tested 632 middle-aged male veteran twins on variants of these tasks in order to compare test difficulty, measure their inter-correlation, test order effects, and estimate heritabilities (proportion of observed variance due to genetic influences). Non-spatial alternation (NSA), which may involve greater reliance on processing of subgoals, was significantly more difficult than spatial alternation (SA). Despite their similarities, NSA and SA scores were uncorrelated. NSA performance was worse when administered second; there was no SA order effect. NSA scores were modestly heritable (h(2)=.25; 26); SA was not. There was shared genetic variance between NSA scores and general intellectual ability (r(g)=.55; .67), but this also suggests genetic influences specific to NSA. Compared with findings from small, selected control samples, high "failure" rates in this community-based sample raise concerns about interpretation of brain dysfunction in elderly or patient samples.     

A/B型人格对时间性前瞻记忆的影响

通过对比A/B两种人格者在执行即无社会关系特征又无个人重要性的时间性前瞻记忆任务时的时间性前瞻记忆成绩和在执行时间性前瞻记忆过程中的时间监控模式,发现A/B型人格的背景任务成绩和TBPM任务成绩都没有显著差异,而时间监视模式有显著差异。说明A型人格被试能更高效的利用认知资源,以更高效和更策略的时间监控模式完成TBPM任务。也说明TBPM是一类与时间监控能力密切相关的前瞻记忆类型。     

Parallel Factor Analysis of gait waveform data: A multimode extension of Principal Component Analysis

Gait data are typically collected in multivariate form, so some multivariate analysis is often used to understand interrelationships between observed data. Principal Component Analysis (PCA), a data reduction technique for correlated multivariate data, has been widely applied by gait analysts to investigate patterns of association in gait waveform data (e.g., interrelationships between joint angle waveforms from different subjects and/or joints). Despite its widespread use in gait analysis, PCA is for two-mode data, whereas gait data are often collected in higher-mode form. In this paper, we present the benefits of analyzing gait data via Parallel Factor Analysis (Parafac), which is a component analysis model designed for three- or higher-mode data. Using three-mode joint angle waveform data (subjects×time×joints), we demonstrate Parafac's ability to (a) determine interpretable components revealing the primary interrelationships between lower-limb joints in healthy gait and (b) identify interpretable components revealing the fundamental differences between normal and perturbed subjects' gait patterns across multiple joints. Our results offer evidence of the complex interconnections that exist between lower-limb joints and limb segments in both normal and abnormal gaits, confirming the need for the simultaneous analysis of multi-joint gait waveform data (especially when studying perturbed gait patterns).     

Cortisol response to behavior problems in FMR1 premutation mothers of adolescents and adults with fragile X syndrome: A diathesis-stress model

Mothers of adolescents and adults with fragile X syndrome (FXS) are faced with high levels of parenting stress. The extent to which mothers are negatively impacted by this stress, however, may be influenced by their own genetic status. The present study uses a diathesis-stress model to examine the ways in which a genetic vulnerability in mothers with the premutation of the FMR1 gene interacts with child-related environmental stress to predict their morning cortisol levels. Seventy-six mothers of an adolescent or adult with FXS participated in an 8-day telephone diary study in which they reported on the behavior problems of their son or daughter with FXS each day. We analyzed salivary cortisol collected from mothers at awakening and 30 minutes after awakening on 4 of these days. The results indicated that mothers with greater genetic vulnerability had a lower level of cortisol on mornings following days when their son or daughter with FXS manifested more episodes of behavior problems, whereas mothers with less genetic risk evinced the opposite pattern of higher morning cortisol in response to their child's behavior problems. This finding contributes to our understanding of gene-by-environment interactions and highlights the importance of interventions to alleviate parenting stress in mothers raising children with FXS.     

身体形式和社会环境对SNARC效应的影响:基于具身认知观的理解

目前SNARC效应在认知心理学领域得到了广泛研究,然而较少有研究考察身体形式和社会环境对SNARC效应的影响.研究以127名在校大学生为被试,使用奇偶判断任务、Go/No-go任务以及合作情境下的Go/No-go任务依次展开了三个研究,拟揭示身体形式和社会环境对SNARC效应的影响.实验一要求被试双手完成奇偶判断任务,结果出现了经典的SNARC效应.实验二要求被试完成Go/No-go任务,并让被试单手(左手或右手)对奇数或偶数进行反应,结果SNARC效应没有出现,这表明认知主体的身体形式对SNARC效应产生了影响.实验三要求被试合作完成Go/No-go任务,该实验按照被试所坐的位置(左边和右边)和反应手(左手和右手),设计了四个条件,结果只有身体位置和反应手完全一致时出现了 SNARC 效应.以上结果一方面表明了具身认知观的合理性,另外一方面扩展了以往对SNARC效应本质的理解.     

Culture and accountability in negotiation: Recognizing the importance of in-group relations

We extend Gelfand and Realo’s (1999) argument that accountability motivates negotiators from relationally-focused cultures to use a more pro-relationship approach during negotiations. Our research shows that the effect they predict is found only when the other negotiating partner is an in-group member. Specifically, in two studies involving participants from China (a relationally-focused culture) and the US (a less relationally-focused culture), we found that only when negotiating with an in-group member are Chinese participants under high accountability more likely to use a pro-relationship approach than those under low accountability. Consequently, the differences between Chinese and American participants in the use of a pro-relationship approach occur only when they negotiate with an in-group member under high accountability. The strong attention to relationships, however, results in higher fixed-pie perceptions and lower joint gains. The implications of our findings for theory and practice are discussed.     

Langzeitergebnisse einer Funktionellen-Magnetresonanztomographie-Studie

In a controlled functional magnetic resonance imaging (fMRI) study the effect of psychodynamic short-term psychotherapy on cerebral activation of panic disorder patients was determined. In a linguistic go-no go paradigm behavioral measures and cerebral activation to affective word stimuli with threatening, neutral and positive content were assessed pretreatment and post-treatment in 9 patients with panic disorder. 18 healthy controls were scanned twice at the same intervals. In an additional long-term follow-up after approximately 3 years post-treatment the effect of brain activation changes during treatment on the long-term outcome of core symptoms (panic-related cognition and fear of body sensations) were determined. In accordance with the hypotheses increased limbic (hippocampus and amygdala) activation accompanied by low prefrontal activation to negative words were found. At treatment termination, panic-related symptoms had improved significantly and fronto-limbic activation patterns were normalized. Reduction of activation of the limbic system during treatment was predictive of a favorable long-term outcome. The results indicate that short-term psychodynamic treatment leads to changes in fronto-limbic networks, similar to previous findings on cognitive-behavioural treatment.     

镜像神经系统—研究药物依赖行为的新靶点

镜像神经是近年来认知与大脑神经科学研究中崭新的课题,大量实验证实了镜像神经元(系统)参与到了多种心理能力的发展与进化之中。目前有研究发现,吸烟相关线索会激活尼古丁成瘾者大脑相应的动作脑区,而该区域也正是人类镜像神经区域,这意味着镜像神经在相关线索激发的心理渴求中可能扮演了重要角色。该实验结果有重要的意义,动作计划脑区的神经线索反应为发展可靠的依赖行为的生物学标记提供了另一个新目标,不仅开发了一个新型的依赖行为的理论模型,还为把神经科学的研究发现运用到实践应用打下了良好的基础。