应激对大鼠行为和部分脑区谷氨酸含量的影响

以旷场试验法测定动物在急、慢性躯体性和心理性应激时的行为变化,以快速断头冷冻匀浆法,用ＨＩＴＡＣＨＩ－８３５氨基酸分析仪测定应激各期视皮层、海马、下丘脑、小脑谷氨酸含量。并对正常动物经侧脑室微量注射Ｌ－ＡＰ４后观察行为变化。结果显示,急性应激期动物行为活动增加,慢性应激期减少：应激时,大鼠部分脑区的谷氨酸含量与对照组相比在不同时期呈显著性差异;侧脑室微量注射Ｌ－ＡＰ４提示行为活动减弱可能与脑内Ｇｌｕ系统的活动有关。     

加压素对记忆巩固过程作用的研究 Ⅱ.GABA在加压素易化记忆巩固过程中作用的探讨

本文探讨了脑内GABA能神经元在加压素易化记忆巩固过程中的作用。结果表明,第三天建立实验后立即腹腔注射印防己毒素(picrotoxin,0.5mg/kg),消除了加压素对条件反应消退过程的延缓作用,而注射氨氧乙酸(aminooxy-acetic acid,20mg/kg)获得相反结果。 实验结果提示,脑内GABA能神经元可能参与了加压素对记忆巩固过程的易化作用。     

Psychopathology in children of parents with recurrent depression

We examined the prevalence of psychopathology in children of parents with recurrent major depression (n=61)and children of normal control parents (n=46).Rates of psychopathology in the children of depressed parents were consistently higher when compared either with the control children or with rates of disorder reported for nonclinically referred children from other studies. Forty-one percent of high-risk children met criteria for at least one psychiatric disorder compared with 15% of low-risk children. Significant differences between groups were found for affective disorders and attention deficit disorder, and a nonsignificant trend was noted for anxiety disorder, all of which were more prevalent in the children of depressed parents.This work was supported, in part, by a W. T. Grant Foundation Faculty Scholar Award, No. 8308700.     

Psychometric properties of the Cognitive Emotion Regulation Questionnaire: Chinese version

The aim of the present study was to develop a Chinese version of the Cognitive Emotion Regulation Questionnaire (CERQ-C) and to examine its psychometric properties in a sample of Chinese university students. The English version of the Cognitive Emotion Regulation Questionnaire was translated and back-translated prior to its administration to 791 participants recruited from two universities in Changsha, Hunan (China). Internal consistency, test–retest reliability, inter-scale reliability, and factorial validity were analysed. The CERQ-C exhibited: (1) moderate internal consistency (Cronbach's α=.83); (2) a mean inter-class correlation coefficient of .79; (3) a mean inter-item correlation coefficient of .09; and (4) moderate test–retest reliability (.64). Confirmatory factor analyses supported the original CERQ nine-factor model. Finally, with respect to criterion validity, several CERQ-C subscales were uniquely associated with symptoms of depression and anxiety.     

汶川地震8.5年后青少年身心状况研究

汶川地震8.5年后,对地震极重灾区的2291名青少年进行问卷调查,考察其创伤后应激障碍(PTSD)、抑郁、创伤后成长(PTG)和生活满意度等身心反应的现状及其共存形态。结果发现:(1)地震发生8.5年后4.75%的青少年有明显的PTSD症状,29.98%的青少年有明显的抑郁症状,其中女生、少数民族学生、高年级学生的症状水平更高;46.13%的青少年报告其出现了明显的PTG,其中女生和少数民族学生的PTG水平更高;青少年的生活满意度较低,其中初一年级显著高于其他年级,但性别和民族差异不显著;(2)青少年的PTSD与抑郁呈显著正相关、与生活满意度呈显著负相关、与PTG相关不显著,抑郁与PTG和生活满意度呈显著负相关,PTG与生活满意度呈显著正相关;(3)青少年的PTSD、抑郁、PTG和生活满意度之间具有共存的形态,具体表现为成长组(32.6%)、低症状组(39.4%)、症状-成长共存组(5.8%)、中等症状共病组(17.8%)和高度症状共病组(4.4%)等5种类别。     

压力对大学生抑郁的影响机制:领悟社会支持与应对方式的中介作用

基于心理应激理论、素质-压力三模式以及社会支持主效果模型考察领悟社会支持、积极应对方式和消极应对方式在压力与抑郁关系中的链式中介效应,使用压力量表、领悟社会支持量表、应对方式量表和抑郁量表对抽取的641名大学生进行调查。研究显示:(1)领悟社会支持中介了压力对大学生抑郁的影响;(2)积极应对方式、消极应对方式中介了领悟社会支持对大学生抑郁的影响。因此,领悟社会支持以及应对方式在压力与大学生抑郁之间起链式中介作用。     

六祖惠能的偈语中的心学思想探究

六祖的偈语是其禅学思想的肇始和集中体现,其中蕴含着丰富的心学思想。概括起来,它所蕴含的心学思想主要表现在以下几个方面:心的本体性与修心; 心无与心存; 心悟; 静心等。这些思想既是一种哲学思想,也是一种宗教思想,同时也是一种人们修心处世之道。它们给予当代人以很大的启迪作用和借鉴价值,在当今社会仍有重要的现实价值。     

Coping,social support,stigma, and gender difference among people living with HIV in Guangxi,China

The current study examined whether gender, HIV-related stigma, social support, and the interaction between gender and social support are associated with coping responses among people living with HIV and AIDS (PLWHA) in Guangxi, China. A total of 2987 PLWHA in Guangxi participated from October 2012 to August 2013. Multivariate analysis of covariance was conducted with gender and social support as main factors in the model, and stigma and other variables as covariates. After controlling for demographic variables and stigma, there were significant main effects of emotional social support (F = 1.61, p < .001), functional social support (F = 1.67, p < .001), and informational social support (F = 3.67, p < .001) on various coping strategies. The interaction between gender and informational social support (F = 1.33, p < .05), internalized stigma (F = 37.03, p < .001) and perceived stigma (F = 9.16, p < .001) were associated with various coping strategies. Findings signify the importance of HIV-related stigma and social support differences in the coping strategies among PLWHA in Guangxi, China.     

Older but not younger infants associate own‐race faces with happy music and other‐race faces with sad music

We used a novel intermodal association task to examine whether infants associate own‐ and other‐race faces with music of different emotional valences. Three‐ to 9‐month‐olds saw a series of neutral own‐ or other‐race faces paired with happy or sad musical excerpts. Three‐ to 6‐month‐olds did not show any specific association between face race and music. At 9 months, however, infants looked longer at own‐race faces paired with happy music than at own‐race faces paired with sad music. Nine‐month‐olds also looked longer at other‐race faces paired with sad music than at other‐race faces paired with happy music. These results indicate that infants with nearly exclusive own‐race face experience develop associations between face race and music emotional valence in the first year of life. The potential implications of such associations for developing racial biases in early childhood are discussed.