对心血管病临床强化治疗的质疑

强化治疗是最近几年反复提到的话题.很多临床试验研究各种强化治疗对心血管疾病预后的影响,但结果显示强化治疗并未能带来更多的益处,甚至有害.因此我们必须理性地看待这些所谓的强化治疗.更应该倾向于个体化治疗、综合治疗,包括控制各种危险因素,改善生活的方式.把治疗的眼光放到疾病发生的早期,早治疗,以求更多获益.     

车文博心理学思想初探

车文博先生是当代中国著名的心理学家,为中国心理学的发展作出了重大贡献.1)推进了中国心理学基本理论的研究,是中国理论心理学科的奠基人之一;2) 推动心理学史的研究,在东、西方心理学史及比较史研究方面均成就斐然;3)重视心理学的实践应用,并积极推进了中国心理学的组织建设与人才培养.     

Chronic administration of troxerutin protects mouse brain against d-galactose-induced impairment of cholinergic system

Previous evidence showed that administration of d-galactose (d-gal) increased ROS production and resulted in impairment of cholinergic system. Troxerutin, a natural bioflavonoid, has been reported to have many benefits and medicinal properties. In this study, we evaluated the protective effect of troxerutin against d-gal-induced impairment of cholinergic system, and explored the potential mechanism of its action. Our results displayed that troxerutin administration significantly improved behavioral performance of d-gal-treated mice in step-through test and morris water maze task. One of the potential mechanisms of this action was decreased AGEs, ROS and protein carbonyl levels in the basal forebrain, hippocampus and front cortex of d-gal-treated mice. Furthermore, our results also showed that troxerutin significantly inhibited cholinesterase (AchE) activity, increased the expression of nicotinic acetylcholine receptor alpha 7 (nAchRα7) and enhanced interactions between nAchRα7 and either postsynaptic density protein 95 (PSD95) or N-methyl-d-aspartate receptors subunit 1 (NMDAR1) in the basal forebrain, hippocampus and front cortex of d-gal-treated mice, which could help restore impairment of brain function.     

基于易感人格的药物成瘾者工作记忆对执行控制功能的调节作用

为了解工作记忆在易感性人格对药物成瘾者执行控制功能和抑制性影响过程中的调节作用,采用BIS和SSS量袁以及连续操作测验（CPT）、2-back任务、威斯康星卡片分类任务（WCST）对150名药物成瘾者和100名年龄、性别及智商相匹配的非药物成瘾者实施冲动性人格、认知控制功能测试。结果发现在2-back任务正确率（工作记忆）高低不同的情况下,注意冲动性人格特质得分对执行控制功能会产生不同的影响。这说明工作记忆在冲动性人格对抑制性的影响中具有调节作用。     

冲动性特质对高中生自杀意念的影响:校园排斥与生命意义感的作用

采用冲动性特质量表、青少年遭受校园排斥问卷、生命意义感量表、自杀意念量表对633名高中生进行调查。结果表明:(1)冲动性特质对高中生自杀意念有显著的正向预测作用;(2)校园排斥在冲动性特质与高中生自杀意念间起部分中介作用;(3)冲动性特质经由校园排斥影响高中生自杀意念的中介作用受生命意义感的调节,随着生命意义感的增加,校园排斥对自杀意念的效应逐步减弱。冲动性特质可以通过校园排斥增加高中生自杀意念强度,而生命意义感能有效降低校园排斥对自杀意念的消极影响。     

Fumerton's Puzzle for Theories of Rationality

Richard Foley has presented a puzzle purporting to show that all attempts in trying to find a sufficient condition of rationality are doomed. The puzzle rests on two plausible assumptions. The first is a level-connecting principle: if one rationally believes that one's belief that p is irrational, then one's belief that p is irrational. The second is a claim about a structural feature shared by all promising sufficient conditions of rationality: for any such condition, it is possible that one's belief satisfies it and yet one rationally believes that it doesn’t. With the two assumptions, Foley argues that a sufficient condition of rationality is impossible. I explain how exactly the puzzle goes and I try to offer a solution. If my solution works, all theorists of rationality who accept certain level-connecting principles need to add an extra condition to their favourite rationality-making condition.     

α系数的区间估计方法比较

多数情况下,α系数可以用来评价测验信度。诸多研究建议,在报告测验信度的时候应当包括其置信区间。通过蒙特卡洛模拟研究,比较了7种α系数区间估计方法,包括Fisher法、Bonett-02法、Bonett-10法、精确Koning-Franses法、渐近ID法、渐近Koning-Franses法和ADF法。结果发现Bonett-10法和精确Koning-Franses法较好,它们的结果相差很小。这两种方法都比较简单,只需要样本的α值、测验题数、被试人数及F临界值,通过简单的运算便可得到α系数的置信区间。     

Perceiving Multiple Affordances for Objects

Researchers (Gilden &; Proffitt, 1989; Runeson &; Vedeler, 1993; Todd &; Warren, 1982) have tested Runeson's (1977) claim that the relation between a collision . . event's dynamics and kinematics might support perception of the relative mass of colliding objects. Results have been inconsistent; however, these studies employed computer-generated collisions as stimuli. The present research assessed observer's ability to report relative mass in the context of physical objects involved in physical collisions. The results indicate greater sensitivity to relative mass than had been found with animations-based studies. Implications of these data for the kinematic specification of dynamics (KSD) principle of dynamics perception (Runeson &; Frykholm, 1983) and a cue-heuristics theory of dynamics perception (Gilden &; Proffitt, 1989) are discussed.     

论班图拉观察学习理论的特征及其历史地位

该文从以下三个方面分析了班图拉观察学习理论的特征：（１）强化与认知的结合,（２）行为主义的建构论,（３）交互决定论。作者认为,班图拉对心理学的杰出贡献是他发掘了观察学习这一前人所忽视的学习形式,给了观察学习以应有的地位。作者认为,班图拉在其观察学习的研究中,注重社会因素的影响。以认知的术语阐述观察学习的过程与作用,且注重以人为被试的实验,因而对学习心理学的发展产生重要影响。