浅析肿瘤疫苗

肿瘤疫苗作为肿瘤特异性主动免疫治疗的方式,目的是激发启动,调节增强机体固有的免疫功能和抗癌能力以维护机体生理平衡。具有使机体由被动抗癌向主动抗癌转变的特点。     

Describing organizations as reinforcer systems: A new use for job satisfaction and employee attitude surveys

Job satisfaction data on managerial personnel were used to illustrate how organizations can be differentiated and described as reinforcer systems. Twenty-seven specific satisfaction scales were regressed on overall job satisfaction, separately for each of five groups of managers from five organizations. For all groups, overall satisfaction was found to be determined mainly by scales concerning challenge of the job and prospects of one's chosen career. Application of decremental stepwise multiple regression procedures to obtain minimum-variable-set equations resulted in different, though overlapping, sets of variables in the equations for the different organizations. These results suggest a way of describing organizations as reinforcer systems, in terms of the specific determinants of overall satisfaction for the organization.     

Modern health worries – the dark side of spirituality?

Modern health worries (MHWs) are widespread in modern societies. MHWs were connected to both negative and positive psychological characteristics in previous studies. The study aimed to investigate the relationships among intuitive‐experiential information processing style, spirituality, MHWs, and psychological well‐being. Members of the Hungarian Skeptic Society (N = 128), individuals committed to astrology (N = 601), and people from a non‐representative community sample (N = 554) completed questionnaires assessing intuitive‐experiential information processing style, spirituality, modern health worries (MHWs), and psychological well‐being. Astrologers showed higher levels of spirituality, intuitive‐experiential thinking, and modern health worries than individuals from the community sample; and skeptics scored even lower than the latter group with respect to all three constructs. Within the community sample, medium level connections between measures of spirituality and the experiential thinking style, and weak to medium level correlations between spirituality and MHWs were found. The connection between MHWs and experiential thinking style was completely mediated by spirituality. Individuals with higher levels of spirituality are particularly vulnerable to overgeneralized messages on health related risks. Official communication of potential risks based on rational scientific reasoning is not appropriate to persuade them as it has no impact on the intuitive‐experiential system.     

Mentoring Relationship Closures in Big Brothers Big Sisters Community Mentoring Programs: Patterns and Associated Risk Factors

Previous research suggests that early mentoring relationship (MR) closures may have harmful consequences for the health and well‐being of youth participating in community‐based mentoring programs. However, knowledge of the factors that lead some MRs to close early has been slow to emerge. This study examined patterns and correlates of early versus on‐time MR closures among 569 youth participating in Big Brothers Big Sisters community mentoring programs. Thirty‐four percent of youth experienced an early MR closure prior to the end of the program's 12 month period of commitment. The probability of closure was highest at 12 months into the MR. Early closures were positively associated with youth gender (girls), behavioral difficulties, and match determination difficulties. Early and on‐time closures were associated with youth extrinsic motives for joining the program. Early MR closures were negatively associated with youth perceptions of parent emotional support, parent social support, high quality MR, weekly contact in MR, and parent support of the MR. Implications for programming are discussed.     

Site preference and alloying effect of tungsten in the μ phase of Co7Mo6

The electronic structures of the μ phase of Co₇Mo₆ were investigated by means of first-principles calculation based on the density functional theory. The calculated equilibrium lattice parameters of Co₇Mo₆ are in good agreement with the experimental results. The results of calculation reveal that the addition of tungsten (W) promotes the stability of the μ phase of Co₇Mo₆ and W tends to participate in its formation. Through analysing the calculated electronic structure (partial density of states and charge density difference), it can be noted that a strong interaction exists due to d–d hybridization. Also, the majority of the atoms may contribute their valence electrons to the formation of metallic bonds in binary and ternary systems. Furthermore, the calculated results show that the doped W atom prefers to occupy the Co site in Co₇Mo₆ μ phase.     

大脑两半球功能不对称性与儿童学业成绩

本研究调查了 3 1 8名小学一至三年级学生大脑两半球优势情况 ,然后对不同优势半球学生的语文和数学成绩进行了比较。结果发现优势半球为右半球的学生人数较少 ,只有 3 .8% ,明显少于优势半球为左半球的学生 (χ2 =2 3 9.83 0 ,p<0 .0 0 1 )。对不同优势半球学生的语文和数学成绩的比较 ,未发现两者有显著差异 (语文 :F=1 .1 3 0 ,p>0 .0 5 ;数学 :F=0 .5 75 ,p>0 .0 5 )。     

学习困难儿童的问题解决特点研究

本研究选取学习困难儿童和正常儿童各 3 2名 ,设置河内塔问题解决的情境 ,采用临床观察法 ,对学习困难儿童在问题解决中的特点作了初步的探究。研究发现 :1与正常儿童相比 ,学习困难儿童在发现和有效运用策略方面明显不足 ,但当学习困难儿童对问题情境比较熟悉后 ,有明显的进步 ;2一定的提示并不能帮助学习困难儿童最有效地应用策略。     

互依性与团队协作

互依性是指团队成员在完成作业的过程中相互依赖的程度,分为作业互依性和产出互依性两大类。该文全面的阐述了互依性的概念、分类和测量方法,并重点介绍了20世纪90年代以后有关互依性在团队协作领域中的研究结果。总结发现,两类互依性与很多团队变量均有显著相关,特别是团队的结果变量。在对结果变量的影响上,两类互依性存在交互作用,或互依性与其他变量存在交互作用。文章最后提出了目前研究的局限性,以及未来的研究展望     

Repeated Play Reduces Video Games’ Ability to Elicit Guilt: Evidence from a Longitudinal Experiment

Statements supported mostly by correlational and cross-sectional studies suggest that playing violent video games can cause emotional desensitization. A longitudinal experiment examined a) whether repeated violent game play leads to emotional desensitization and b) whether desensitization generalizes to other play and real-life experiences. Participants played alternative versions of the same violent game for the first four days; on these days, the character role was varied between-subjects to be moral (United Nations soldier) or immoral (terrorist soldier). On Day 5, all participants played a novel game as a terrorist. Results indicate two things. First, habituation occurs over repeated game play: Repeated exposure decreased the ability of the original game to elicit guilt. Second, the decreased ability to elicit guilt can generalize to other game-play experiences: Guilt elicited by the novel game on Day 5 was reduced for the immoral character condition compared to the moral character condition. The current study provides causal, longitudinal evidence regarding the potential for video game play to lead to emotional desensitization with regard to future video game-play experiences.