Neonatal odor-shock conditioning alters the neural network involved in odor fear learning at adulthood

Adult learning and memory functions are strongly dependent on neonatal experiences. We recently showed that neonatal odor-shock learning attenuates later life odor fear conditioning and amygdala activity. In the present work we investigated whether changes observed in adults can also be observed in other structures normally involved, namely olfactory cortical areas. For this, pups were trained daily from postnatal (PN) 8 to 12 in an odor-shock paradigm, and retrained at adulthood in the same task. (14)C 2-DG autoradiographic brain mapping was used to measure training-related activation in amygdala cortical nucleus (CoA), anterior (aPCx), and posterior (pPCx) piriform cortex. In addition, field potentials induced in the three sites in response to paired-pulse stimulation of the olfactory bulb were recorded in order to assess short-term inhibition and facilitation in these structures. Attenuated adult fear learning was accompanied by a deficit in 2-DG activation in CoA and pPCx. Moreover, electrophysiological recordings revealed that, in these sites, the level of inhibition was lower than in control animals. These data indicate that early life odor-shock learning produces changes throughout structures of the adult learning circuit that are independent, at least in part, from those involved in infant learning. Moreover, these enduring effects were influenced by the contingency of the infant experience since paired odor-shock produced greater disruption of adult learning and its supporting neural pathway than unpaired presentations. These results suggest that some enduring effects of early life experience are potentiated by contingency and extend beyond brain areas involved in infant learning.     

Predictors of perceived susceptibility to sport-related injury

Little is known about factors associated with perceptions of susceptibility to sport-related injuries. The purpose of the present study was to examine previous experiences with injury and personality factors as predictors of rugby players’ perceived susceptibility to injury. In line with an individual-based approach, it was hypothesized that neuroticism and global self-esteem would be related to perceived susceptibility to sport injuries over and above previous experiences with injuries. Rugby players (N = 235) were asked to report about previous experiences with injury and were administered measures of neuroticism and global self-esteem. Multiple regression analysis revealed that previous experiences with injury were positively related to perceived susceptibility to sport-related injuries. Analyses also supported that neuroticism and global self-esteem are of crucial importance in colouring perceptions of susceptibility to sport-related injury, while statistically controlling for previous injuries. Of particular interest, neuroticism predicted perceived susceptibility, over and above global self-esteem and previous experiences with injury. This study is the first to focus on determinants of perceived susceptibility to sport-related injury and supports the potential role of personality factors and individual dispositions in shaping perceived susceptibility to health problems.     

On the social nature of global self-esteem: a replication study

Few researchers have considered the relationship between global self-esteem and the reflected appraisal of others in one's life, or how reflected appraisals and global self-esteem may change as a result of interpersonal feedback. In this study, the authors collected data from 110 undergraduate students on (a) their global self-esteem and the reflected appraisals of multiple others in their lives and (b) how these dimensions changed in hypothetical interpersonal-feedback situations. Results showed that participants' global self-esteem was related to the reflected appraisals of their fathers, teachers, and friends. The results also indicated that others' reflected appraisals and the individual's global self-esteem fluctuated according to the nature (i.e., positive vs. negative) of the hypothetical interpersonal feedback. Overall, the findings emphasize the social nature and regulation of global self-esteem.     

Bending rules: the shape of the perceptual generalisation gradient is sensitive to inference rules

Generalising what is learned about one stimulus to other but perceptually related stimuli is a basic behavioural phenomenon. We evaluated whether a rule learning mechanism may serve to explain such generalisation. To this end, we assessed whether inference rules communicated through verbal instructions affect generalisation. Expectancy ratings, but not valence ratings, proved sensitive to this manipulation. In addition to revealing a role for inference rules in generalisation, our study has clinical implications as well. More specifically, we argue that targeting inference rules might prove to be an effective strategy to affect the excessive generalisation that is often observed in psychopathology.     

An evaluation of scanpath-comparison and machine-learning classification algorithms used to study the dynamics of analogy making

In recent years, eyetracking has begun to be used to study the dynamics of analogy making. Numerous scanpath-comparison algorithms and machine-learning techniques are available that can be applied to the raw eyetracking data. We show how scanpath-comparison algorithms, combined with multidimensional scaling and a classification algorithm, can be used to resolve an outstanding question in analogy making—namely, whether or not children’s and adults’ strategies in solving analogy problems are different. (They are.) We show which of these scanpath-comparison algorithms is best suited to the kinds of analogy problems that have formed the basis of much analogy-making research over the years. Furthermore, we use machine-learning classification algorithms to examine the item-to-item saccade vectors making up these scanpaths. We show which of these algorithms best predicts, from very early on in a trial, on the basis of the frequency of various item-to-item saccades, whether a child or an adult is doing the problem. This type of analysis can also be used to predict, on the basis of the item-to-item saccade dynamics in the first third of a trial, whether or not a problem will be solved correctly.     

Impaired oral reading in two atypical dyslexics: a comparison with a computational lexical-analogy model

A computational model of reading was developed based upon the notion that the structural relationship between orthography and phonology is of greater importance than the dimension of semantics for the reading aloud of single words. Degradation of this model successfully simulated the reading performance of two patients with atypical acquired dyslexia. The first patient CAV, studied and described in the literature by Warrington in 1981, presented with unusual concrete word dyslexia, i.e., he had a category-specific reading deficit for concrete words compared with abstract words. The second patient BG is a phonological dyslexic who, although displaying a strong concreteness effect (concrete words read better than abstract words), was able to read functors individually perfectly well, a pattern that is rarely if ever seen. The computational model was used to generate a set of words for which it was predicted that BG would show no concreteness effect. The results of BG's reading of these words were consistent with this prediction, thereby providing greater support for the validity of the model. It is concluded that a computational approach that attempts not only to reproduce the core symptoms of the major varieties of acquired dyslexia but also to simulate clinical data from specific patients has much to contribute to the understanding of cognitive deficits and to the design of effective rehabilitation strategies.     

Investigating secondary‐distinctiveness‐based effects in aging and Alzheimer's disease patients

The aim of the present study was 2‐fold. First, two experiments were devised to further investigate secondary distinctiveness‐based effects in relation to aging. By using a repeated study‐test procedure, it aimed at restoring the bizarreness effect (Experiment 1) or at amplifying the orthographic distinctiveness (OD) effect in older adults (Experiment 2). Second, by including Alzheimer's disease patients (AD patients) in both experiments, it also aimed at instigating research on secondary distinctiveness‐based effects in relation to Alzheimer disease. The results of Experiment 1 revealed that a repeated study‐test procedure may to some extent facilitate the free recalling of bizarre images in older adults. However, the benefit of such procedure does not seem to be durable in older adults (no bizarreness effect for the last study‐test cycle) and is inefficient in AD patients. Surprisingly, for both older adults and AD patients, results of Experiment 2 revealed a similar OD effect across all study‐test cycles. The findings of both experiments were related to previous work suggesting that the bizarreness effect and the OD effect are mediated by different processing.     

Beliefs about age-related changes in physical functioning across the adult life span and their relationship with physical activity levels of older adults

Physical activity declines across the adult life span despite the well-established links between physical activity and health-related, psychological, cognitive, and social benefits. We contrasted the beliefs young and older adults hold about how aging affects both physical abilities and physical activity and determined whether older adults’ beliefs about physical aging relate to their engagement in physical activity. Using visual rating scales, 56 young and 49 community-dwelling older adults indicated the extent to which a typical woman or typical man aged 20–90 possesses six different physical abilities and engages in three different types of physical activity. Stereotypes of physical aging were ability- and activity-specific, and older adults endorsed more positive views than their younger peers. Stereotypical beliefs predicted older adults’ engagement in moderate-intensity activity. This study offers intriguing avenues for future research and suggests that better understanding physical aging stereotypes may contribute toward designing interventions that promote lifelong physical activity.     

Cognitive Processes Underlying Observational Learning of Motor Skills

There is evidence indicating that an individual can learn a motor skill by observing a model practising it. In the present study we wanted to determine whether observation would permit one to learn the relative timing pattern required to perform a new motor skill. Also, we wanted to determine the joint effects of observation and of physical practice on the learning of that relative timing pattern. Finally, we were interested in finding whether there was an optimal type of model, advanced or beginner, which would lead better to observational learning. Data from two experiments indicated that observation of either a beginner or an advanced model resulted in modest learning of a constrained relative timing pattern. Observation also resulted in significant parameterization learning. However, a combination of observation followed by physical practice resulted in significant learning of the constrained relative timing pattern. These results suggest that observation engages one in cognitive processes similar to those occurring during physical practice.