自闭症谱系障碍社交动机理论：机制及干预探索

自闭症谱系障碍(Autism Spectrum Disorder, ASD)表现为社会交往困难以及重复刻板兴趣或行为。社交动机理论提出ASD个体是由于社交动机缺乏导致的社交障碍。目前该理论缺乏理论元素及结构关系的系统论证, 及基于此理论的低龄ASD儿童群体的研究证据。本研究拟采用心理实验法、眼动及近红外脑成像技术, 探索低龄ASD儿童早期社交奖赏、社交定向异常眼动标记及眶额叶脑区活动的神经机制。此外, 通过音乐奖赏强化学习的干预方式改善该理论的核心元素(社交奖赏), 观测能否改善ASD儿童的社交动机。本研究的开展有望对该理论进行系统验证, 并形成改善社交行为的潜在干预方案。     

跨期选择的变易程度正向预测中华文化圈国民的自评扛疫成效：亚非欧美大洋洲18国跨国研究

跨期选择是对不同时间点的得失的权衡与选择。伊索寓言《蚂蚁和蚱蜢》假借群居型昆虫的跨期选择偏爱暗喻投资未来的慢策略比只顾眼前的快策略更利于生存。用跨期选择领域通用的语言解读这一寓言便是：选择大而迟选项的蚂蚁比选择小而早选项的蚱蜢更可能扛过严冬而生存下来。为了探索何种跨期选择策略更有助于我们扛过疫情,本研究调查了亚非欧美大洋洲这5大洲18个国家共计26355名受测者对混合得失双结果的跨期选择偏爱,测量了人们平时和疫时跨期选择偏爱的变易程度(2类变易的程度指标),以及人们自评的扛疫成效。跨文化比较结果的主要发现是：不同通货的选择变易程度(指标1)和不同时期的选择变易程度(指标2)能联合预测中国/新加坡文化圈国民的自评扛疫成效;不同时期的选择变易程度(指标2)也可以单独预测印度/马来西亚/菲律宾/尼日利亚文化圈国民的自评扛疫成效;这2类选择偏爱变易的程度指标不能预测其他文化圈国民的自评扛疫成效(或者预测方向和假设相反)。基于易经“穷则变,变则通”的要旨和跨国比较的发现,我们认为：面临历史危机时善于变通的特长抑或成就了中华民族特有的竞争优势;在应对危机时,与中国文化距离越相近的国家或民族抑或也能...     

双眼深度感知与图像元素数量的关系

用微机化的伪随机点立体图对发生器产生静态和动态随机点立体图对(RDS),显示在左右两个示波器上。RDS图形中的元素密度可以改变。具有正常立体视的10名被试通过立体镜观察这些图形,测量双眼融合能产生完整立体图形感知所需最小的元素密度,即密度容限。 设计了三个实验用以检测改变RDS图形的空间参数对密度客限的影响。第一个实验,在静、动态RDS图形下,改变视差图形面积;第二个实验,改变视差图形的形状;第三个实验,改变视差图形的周长。 实验结果表明,双眼深度感知要求一定的元素密度容限,视差图形的大小和形状对密度容限有一定程度的影响。静态和动态RDS图形的密度容限也不相同。 本文利用RDS的整体立体感知特性和空间频率通道理论对实验结果进行了讨论。     

学前儿童对汉语副词的理解和运用

在汉语中,副词是一种比较独特的词类,它没有具体形象的物体可作为理解支柱,因而儿童对它的掌握较晚。在各类副词中,５、６岁儿童对范围副词的理解最佳,时间副词次之,程度副词最差。三者的差异均有非常显著性意义。即使在每一类副词中,由于儿童概念发展的不均衡性,掌握的顺序也有先后。     

Teaching simple addition to children with mental retardation using a microcomputer

Computer assisted instruction (CAI) was used for improving the efficiency of simple addition (single-digit without carrying) computation in three children with mental retardation. The training program, conducted on a portable personal computer, consisted of demonstrations and repetitive practices on simple addition presented in a vertical format. A number of behavioral instruction techniques such as direct feedback, corrective demonstration, verbal association, and token reinforcement were also included. To evaluate the effects of the CAI package, a multiple-baseline across subjects design with followup was employed. Results showed that performances of children improved with training and were maintained at 1-week, 4-week, and 12-week followups. Generalization of the learned skills was evident when children were assessed on a paper-and-pencil addition test in a vertical format. The skills were also transferable, with initial prompting, to a computerized addition test in a horizontal format. These findings reaffirmed the applicability of CAI and behavioral techniques for teaching math skills to children with mental retardation.     

Teaching spontaneous requests to children with autism using a time delay procedure with multi-component toys

Children with autism were taught spontaneous requests through a time delay procedure. Unlike previous research, which usually employed food as the target stimuli to be requested, the present study used toy pieces from multi-component toys. The procedure involved presenting a child with the target stimulus, with the trainer prompting the child by immediately modeling the request response. When the response was imitated without error, prompting was delayed with the time interval gradually being increased over trials. A spontaneous or imitated response was reinforced by giving the child the requested object. As the stimulus/model interval increased, children with autism were expected to initiate the request by themselves prior to the prompt. The efficacy of the time delay procedure was assessed using a multiple baseline across subject design with three Chinese boys with autism. Results showed that the three children acquired a 100% performance within five to nine sessions of training and the skill was maintained at the one-month and three-month followups. Furthermore, the learned response transferred to various conditions when tested across setting, person, toy, and food items. These results suggest that toys, the multi-component ones in particular, served well as reinforcers for language training. Furthermore these findings confirmed the practical utility of the time delay procedure for promoting spontaneous communication skills in children with autism.     

死亡凸显对自我姓名注意瞬脱对抗效应的影响

已有研究表明死亡凸显会抑制自我面孔和自我参照记忆加工的自我优势,可是死亡凸显对自我姓名的影响尚不明确,本研究采用事件相关电位技术,探索死亡凸显对自我姓名注意瞬脱对抗效应及其大脑神经活动的影响。58名被试在经历不同的启动任务后,完成自我姓名、朋友姓名和名人姓名的注意瞬脱任务。行为结果发现自我姓名识别正确率显著高于朋友姓名和名人姓名,表现出稳定的自我姓名加工的注意瞬脱对抗效应;电生理数据发现死亡启动后自我姓名诱发的P300波幅显著低于消极启动组和中性启动组,而朋友姓名和名人姓名并不受启动的影响。本研究结果与以往研究结果共同表明死亡想法凸显会使个体将抑制自我加工（自我姓名、自我面孔和自我参照记忆）作为应对远端死亡焦虑的一种手段。     

一氧化氮在新生儿缺氧缺血性脑病中的作用

在围产期窒息引起的新生儿缺氧缺血性脑病(HIE)中,一氧化氮(NO)对脑组织具有神经保护性和神经毒性双重效应,这取决于NO的来源.并且NO与谷氨酸及内皮素(ET)相互作用.应用哲学观点深入研究NO的作用机制对于探讨HIE的防治具有重要意义.     

A Holist Deontological Solution to the All or Nothing Problem

Philosophia - The All or Nothing Problem is a paradox developed in recent debates about effective altruism. One argues that the paradox can be resolved by rejecting some of its claims in favor of...