Effects of an Extracurricular Science Intervention on Science Performance, Self-Worth, Social Skills, and Sexist Attitudes of Taiwanese Adolescents from Single-Parent Families

A one group pretest-posttest design was used to investigate effects of an extracurricular science intervention on female and male junior high school students’ science performance, self-worth, social skills, and sexist attitudes. Twenty-eight 8th grade Taiwanese students (16 boys, 12 girls) from single parent families participated in this study. Student responses to a questionnaire measuring their self-worth, social skills, and sexist attitudes, and interviews and classroom observations used for triangulation and consolidation of qualitative findings revealed that girls improved significantly on several indices of science performance, and that both boys and girls decreased their sexist attitudes. Girls had significantly less sexist attitudes than boys at both pretest and posttest. Implications for practice and research are provided.     

联结竞争对听写困难儿童形音联结编码的影响

听写困难是一种发生率较高的儿童学习障碍现象。听写困难的认知机制,主要包括语音加工缺陷、字形表征缺陷以及形音联结编码缺陷。本研究通过两个实验,考察了整字语音竞争和部件语音竞争,对听写困难儿童形音联结编码的影响。结果发现,在不同条件下,听写困难儿童的形音联结水平都落后于正常儿童;整字语音竞争显著干扰了正常儿童的形音联结编码,但对听写困难儿童的影响并不明显;与之相反的是,部件语音竞争对听写困难儿童的干扰更为明显。研究结果支持听写困难儿童的形音联结编码缺陷理论。在此基础上,听写困难儿童的形音联结较少受到整字语音的竞争干扰,但更容易受到部件语音的竞争干扰,这可能是因为,他(她)们的整体字形加工或表征存在缺陷,导致原生字字形和语音信息难以被激活,以及合体字的部件信息得到更多的加工所致。     

“阳刚”还是“清秀”更具吸引力?——对男性面孔二态性不同偏好的元分析

生活中,有的喜欢"清秀"的男性面孔,而有的则更偏爱长得"阳刚"的面孔,已有大量的研究致力于解释这一分歧,但是得出的研究结果各不一致。本研究用元分析方法考察对男性面孔二态性的不同偏好,通过检索、搜集了23篇有效文献,56对数据满足了元分析标准(n=8408)。结果发现,漏斗图和BeggMazumdar秩相关检验、Egger’s检验结果显示不存在发表偏差;主效应检验发现对男性面孔二态性无明显偏好;调节效应检验表明,对男性面孔二态性偏好受面孔生成技术、生理周期的调节,但不受被试性别、关系背景和文化的调节。人们对男性面孔二态性的偏好,除了本身生物学特质(生理周期)外,还受到生成技术的影响。     

内生意图性抑制:自我控制研究的新视角

行为抑制的"停止信号"多来自内生意图行为"是否做"决策过程最后时刻内生性否定指示(即内生意图性抑制),而非环境提前设定。因无法用行为指标(错误率、反应时)评估,需将"自由选择"范式结合f MRI、EEG等技术测量与之相关的脑神经、自主神经生理特点;此外,范式中加入的刺激阈下启动、情绪信息影响了内生意图性抑制的加工过程。未来从三个方面拓展研究:(1)明确背内侧额叶皮质的心理机制;(2)探索人格特质的影响;(3)"停止信号"内生日常化。     

情绪唤醒影响记忆巩固过程的神经生理机制

白鼠和人类都对情绪唤醒的经历有更好的记忆。情绪唤醒影响记忆巩固的神经生理机制主要有以下几种方式:(a)情绪唤醒或急性应激,会引发个体内部应激激素的释放,从而增强其记忆巩固过程。(b1)杏仁核的激活对情绪唤醒影响记忆巩固过程十分重要,杏仁核内部去甲肾上腺素(NE)的释放影响记忆巩固过程。(b2)杏仁核投射到负责不同类型记忆加工的脑区,如海马和皮层,从而影响记忆。(c)应激激素影响记忆巩固的过程中,杏仁核内NE的激活在这一过程中扮演着重要角色。综上,情绪唤醒影响记忆巩固的过程,涉及到激素调节、神经调节及二者的共同作用。     

Thy-1肿瘤标记物在肝癌的表达及意义研究

探讨Thy-1（又称CD90）表达与肝癌进展的关系。采用免疫组化法检测组织中Thy-1表达,流式细胞术检测外周血CD45^-CD90^＋细胞百分数。结果Thy-1在肝癌有不同程度表达,随病理级别和临床分期增高,表达也增多。故得出结论,Thy-1与肿瘤进展关系密切,检测Thy-1表达对肝癌的预后评估有实用价值。     

试论我国病人权利保护机制的完善

保护病人的权利直接关系到人权保障,已成为社会热点问题.在分析我国病人权利保护的现状和存在问题的基础上,提出了在制度、观念、社会自治等层面如何改进的举措,主要包括推进医院管理体制改革、法律规范的完善、健全行业自治规范、推进社会自治、建设和谐医患关系等方面.     

由网络成瘾列为精神疾病反思医学化倾向

由于精神疾病的诊断特点,精神科中的医学化现象尤为突出.但精神科的这种现象会产生不当的行为控制、个体与社会的隔阂等弊端.一些网络成瘾的矫治措施限制或剥夺被矫治青少年的人身自由,有的已经带有对精神病性障碍患者进行强制性医疗的色彩.网络成瘾目前归为精神疾病的科学依据不足、容易引起误解和误导,是医学化在精神科中的又一表现.     

Prevalence and Characteristics of Patients with Suspected Inherited Renal Cell Cancer: Application of the ACMG/NSGC Genetic Referral Guidelines to Patient Cohorts

Patients with suspected hereditary renal cell cancer (RCC) are under-referred for genetic evaluation. Characterizing the prevalence and characteristics of suspected inherited RCC is a crucial step toward advancing personalized, genetically-based cancer risk management for patients and their families. To evaluate the prevalence and characteristics of suspected inherited RCC syndromes based on consensus criteria, we performed a cross-sectional analysis of patients with a diagnosis of RCC in SEER (2001–2011, n = 105,754) and in our institutional cancer registry (2004–2013, n = 998). Consensus criteria for referral of patients with RCC for genetic evaluation from the American College of Medical Genetics and Genomics and National Society of Genetic Counselors (ACMG/NSGC) were applied to the two cohorts. The associations between meeting referral criteria with demographic characteristics were assessed with chi-square tests. Overall, 24.0 % of the SEER cohort and 33.7 % of our institutional cohort met ACMG/NSGC referral criteria for genetic counseling. While white patients more commonly met early onset clear cell RCC criteria, black patients met papillary RCC criteria at twice the rate of whites in both cohorts (p < 0.0001). As many as 1 in 5 individuals with RCC meet referral criteria for genetic evaluation based on newly emerging guidelines, with differences in pathology noted by race. Prospective genetic testing studies utilizing emerging referral guidelines should help to refine the genetic spectrum of inherited kidney cancer. This study supports efforts to increase awareness of referral of patients with RCC for genetic counseling particularly among urologic providers.     

系统论引领帕金森病治疗思路

帕金森病的病因、不单是多巴胺的缺失或减少,西医学的多巴胺替代疗法忽略了帕金森病发病的复杂性和整体性;中医的辨证论治缺乏对系统内部的深入研究,带有很大的主观性和盲目性。而在系统论指导下的结构还原,深化了对帕金森病的中西医发病机制的系统认识。中西医结合治疗是还原论和系统论的统一,是帕金森病系统治疗的最佳形式。