人工肝支持系统治疗肝衰竭的研究进展

目前肝衰竭发病率和病死率仍然较高,肝衰竭成为威胁患者生命的严重疾病。基于肝脏具有强大再生能力,人工肝支持系统作为一种“过渡”措施,为肝衰竭患者的肝功能恢复赢得时间。人工肝支持系统根据性质不同分为非生物型人工肝、生物型人工肝和混合型人工肝。目前非生物型人工肝已在肝病治疗领域被广泛应用,但生物型及混合型人工肝的临床应用还存在很多问题需要进一步研究和解决。因此本文对人工肝的作用、临床应用现状、存在问题及研究进展进行综述。     

Dispositional Mindfulness,Posttraumatic Stress Disorder Symptoms and Academic Burnout in Chinese Adolescents Following a Tornado: The Role of Mediation through Regulatory Emotional Self-Efficacy

Limited research has been conducted on dispositional mindfulness, posttraumatic stress disorder (PTSD) symptoms and academic burnout in Chinese adolescents following a tornado. The present study investigated the ways in which dispositional mindfulness is related to PTSD symptoms and academic burnout in Chinese adolescents following a tornado by considering the role of regulatory emotional self-efficacy. A total of 431 Chinese adolescents (mean age: 14.75 years) who had experienced a severe tornado 9 months prior to this study were recruited for this study. The results indicated that our model fit the data well [χ²/df = 2.774, CFI = 0.952, TLI = 0.934, RMSEA (90% CI) = 0.064 (0.051–0.077)], and revealed that regulatory emotional self-efficacy partially mediates the relationships between dispositional mindfulness and PTSD symptoms and academic burnout, respectively. The clinical implications and limitations of our research, and recommendations for future research, are discussed in this paper.     

Parental Health and Children’s Functioning in Immigrant Families: Family Roles and Perceived Treatment at School

Although parents’ health condition is generally thought to be related to their involvement in their children’s functioning, the possible dynamics behind the scenes in school contexts with immigrant children has received little attention. This study examined the association between parents’ health condition and their children’s academic and behavioral functioning, as well as the mediation effects of parents’ school engagement and children’s perceived treatment at school among 607 immigrant families with 10- to 12-year-old children. Using structural equation modeling, the results indicated that parents’ poor health condition was associated with children’s increased behavioral problems. Parents’ school engagement fully mediated the association between parental health condition and children’s academic achievement and partially mediated the association between parental health condition and children’s behavior problems. Notably, higher levels of parents’ school engagement were associated with increased behavior problems, demonstrating a unique feature in these immigrant children’s developmental functioning. Higher levels of perceived harsh treatment by peers at school due to children’s immigrant identity were associated with these children’s greater risks of behavior problems. The results suggested what may lie behind the scenes in these children’s behavioral problems is that many of these children who act out and are brought to the school office for disciplinary issues may suffer from perceived discrimination and bad treatment by their peers. The findings provide important implications for researchers, healthcare practitioners, and educators seeking to understand this subpopulation and to design and implement family support and prevention programs for young adolescents from immigrant backgrounds.     

Grammatical Aspect in Early Child Mandarin: Evidence from a Preferential Looking Experiment

The study assessed 30-month-old Mandarin-speaking children’s awareness of aspectual distinctions involving the perfective marker le and the imperfective marker zhe in a preferential looking experiment. In the experiment, we presented our child subjects with a choice between two video clips (one depicting a closed event and the other depicting an on-going event), in the presence of an auditory stimulus (either the le sentence, the zhe sentence or the control sentence without any aspect marker). Children’s looking behavior in the task was recorded and analyzed. The results revealed 30-month-old children’s emerging sensitivity to the aspectual contrast between le and zhe. This was manifest by an increase in looking to the closed event when hearing the le sentence and an increase in looking to the on-going event when hearing the zhe sentence. The absence of le or zhe in the control sentence did not result in any increase or decrease in looking to either event. We also found that the effect of le on children’s looking behavior was immediate whereas the effect of zhe was late. We attributed this difference to the facilitative role of le in children’s sentence processing as well as their preference for the event boundary. The results lend support to the continuity view that functional morphemes like aspect markers are available to children early in language development.     

教师支持与心理素质对中学生学业成绩的影响

采用学生感知教师支持行为问卷和中学生心理素质问卷,对西南地区两所中学7~12年级的824名在校中学生进行调查研究,探讨教师整体支持和不同类型支持与中学生学业成绩的关系及心理素质在其中的中介作用。结果发现：（1）教师整体支持与中学生心理素质、学业成绩间存在显著正相关;教师情感支持与中学生心理素质、学业成绩间存在显著正相关,教师学习支持、能力支持与中学生心理素质存在显著正相关,但与学业成绩相关均不显著;（2）控制性别和年龄后,心理素质在教师整体支持与学业成绩的关系中起完全中介作用;心理素质在教师情感支持与学业成绩关系中起部分中介作用,在教师学习支持与学业成绩、教师能力支持与学业成绩关系中均起完全中介作用。     

Counterfactual comparison modulates fairness consideration in the mini‐ultimatum game: An event‐related potentials study

Existing literature on the mini‐ultimatum game indicates that counterfactual comparison between chosen and unchosen alternatives is of great importance for individual's fairness consideration. However, it is still unclear how counterfactual comparison influences the electrophysiological responses to unfair chosen offers. In conjunction with event‐related potentials’ (ERPs) technique, the current study aimed to explore the issue by employing a modified version of the mini‐ultimatum game where a fixed set of two alternatives (unfair offer vs. fair alternative, unfair vs. hyperfair alternative, unfair offer vs. hyperunfair alternative) was presented before the chosen offer. The behavioral results showed that participants were more likely to accept unfair chosen offers when the unchosen alternative was hyperunfair than when the unchosen alternative was fair or hyperfair. The ERPs results showed that the feedback‐related negativity (FRN) elicited by unfair chosen offers was insensitive to the type of unchosen alternative when correcting for possible overlap with other components. In contrast, unfair chosen offers elicited larger P300 amplitudes when the unchosen alternative was hyperunfair than when the unchosen alternative was fair or hyperfair. These findings suggest that counterfactual comparison may take effect at later stages of fairness consideration as reflected by the P300.     

人脑加工自我参照任务的时空特点:来自ERP的证据

以自我参照加工任务为范式,实验采用事件相关电位(ERP)技术,探讨了自我参照加工中符合判断和不符合判断加工的时间进程和大脑神经机制。结果发现,自我参照加工在时间上可以概括分为三个阶段:注意分配阶段N1(80~150 ms)波幅出现自我参照结果的差异;语义整合阶段N2(250~450 ms)波幅和潜伏期出现自我参照结果的差异;评价判断阶段P3(450~700 ms)波幅和潜伏期出现自我参照结果的差异。从我们选择的大脑兴趣区激活水平上分析发现,自我信息在大脑中的激活似乎是一个由右及左,由后及前再及后的动态变化过程。研究结果丰富了自我参照加工的已有结果,并且对未来研究具有一定的启示意义。     

考试焦虑者注意偏向的认知与神经机制

应用情绪版本的外部线索任务,以高中生为研究对象,探讨考试焦虑的产生是由负性刺激的警觉还是脱离困难导致的认知神经机制,以及这种注意偏向(警觉与脱离成分)发生的具体时间进程。行为实验结果发现,相比起低考试焦虑个体,高考试焦虑个体对考试相关威胁刺激存在注意脱离困难。脑电实验结果中,P1成分揭示高考试焦虑者对考试相关和无关威胁线索后靶刺激的注意处理削弱;考试相关威胁线索后靶刺激诱发的P300对于高、低考试焦虑者具有临床鉴别的潜力。     

Burger or yogurt? Indulgent consumption in impression management contexts

We conducted three studies to investigate indulgent choice in settings with and without impression management by public–private manipulation with evaluation. Study 1 showed that the participants were less indulgent under public scrutiny due to the employment of impression management. Study 2 focused on the impression management context to test the moderate effect of self‐consciousness in two impression managed contexts. Study 3 focused on context without impression management to test the moderate effects of self‐awareness on choices. We found that depending on differences in primed personality, individuals tended to make choices other than those they favoured privately when anticipating that others might form impressions of them based on the decisions made. The findings of all three studies support our basic prediction that people are less indulgent under impression management and suggest that people tend to manage their impression by eating healthier (less indulgently) in public.