自闭症谱系障碍社交动机理论：机制及干预探索

自闭症谱系障碍(Autism Spectrum Disorder, ASD)表现为社会交往困难以及重复刻板兴趣或行为。社交动机理论提出ASD个体是由于社交动机缺乏导致的社交障碍。目前该理论缺乏理论元素及结构关系的系统论证, 及基于此理论的低龄ASD儿童群体的研究证据。本研究拟采用心理实验法、眼动及近红外脑成像技术, 探索低龄ASD儿童早期社交奖赏、社交定向异常眼动标记及眶额叶脑区活动的神经机制。此外, 通过音乐奖赏强化学习的干预方式改善该理论的核心元素(社交奖赏), 观测能否改善ASD儿童的社交动机。本研究的开展有望对该理论进行系统验证, 并形成改善社交行为的潜在干预方案。     

Irrelevant behaviour,information processing and arousal homeostasis

Summary This paper expands a new hypothesis on the causal mechanisms underlying irrelevant behaviour. It begins with a critical summary of earlier theories which attempted to explain displacement activities, but failed to predict the consistency with which certain types of behaviour are shown in stressful situations by a variety of species. Behavioural and physiological studies suggest that these behaviour patterns are closely associated with the incipient activation of sleep. The functional significance of this link and some of the causal processes which may be responsible for it are discussed. Paradoxically, however, displacement activities occur when animals are in a state of high arousal. The concept of arousal is reconsidered in the light of information theory and assumed to be closely correlated with the information processing rate in the nervous system. The relationships between neural and autonomic arousal are considered in this context. It is argued that over-arousal may occur when information handling exceeds the limited channel capacity of the system, with a consequent loss of efficiency. It is pointed out that there are mechanisms capable of controlling the information influx into the brain, and it is hypothesized that they are tied up in a feedback mechanism which regulates arousal and which involves the activation of a de-arousal system, corresponding to the neurological sleep mechanism. Displacement activities are viewed as consequences of this regulatory activation of the sleep system. This hypothesis is then compared with existing theories of displacement and its relationship with them is discussed.

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Zusammenfassung Die Arbeit erweitert eine neue Hypothese über die kausalen Mechanismen, die dem übersprungverhalten zugrunde liegen. Sie beginnt mit einer kritischen Übersicht der früher vorgeschlagenen Theorien und zeigt auf, daß diese nicht die Beständigkeit, mit der gewisse Verhaltensweisen von einer Anzahl von Tierarten in Stress-Situationen gezeigt werden, erklären. Verhaltens- und physiologische Studien deuten an, daß diese Verhaltensweisen in einem engen Zusammenhang mit einer partiellen Schlafaktivierung stehen. Die funktionelle Bedeutung dieses Zusammenhanges und die möglichen physiologischen Mechanismen, die dafür verantwortlich sein könnten, werden diskutiert. Paradoxerweise werden aber Übersprungsverhalten dann gezeigt, wenn sich Tiere in einem gesteigerten Wachzustand befinden. In diesem Zusammenhang wird das Arousal-Konzept im Lichte der Informationstheorie neu beleuchtet und es wird angenommen, daß der Arousal-Zustand eines Tieres im engen Zusammenhang mit der jeweiligen Informationsverarbeitungsrate im Nervensystem steht. Die Verhältnisse zwischen neuralem und autonomischen Arousal werden diskutiert. Es wird vorgeschlagen, daß sich Überarousal dann einstellt, wenn die Informationsverarbeitungsrate die Kanalkapazität des Systems übersteigt mit einem sich daraus ergebenen Wirkungsgradverlust. Es wird darauf hingewiesen, daß es Mechanismen gibt, die den Informationsfluß in das Gehirn regeln und angenommen, daß diese innerhalb eines Rückkopplungssystems funktionieren, welches Arousal reguliert. Diese Regelung benötigt die Aktivierung eines Arousal herabsetzenden Systems, das in den neurologischen Schlafmechanismen besteht. Das Auftreten von Übersprungsverhalten wird als eine Konsequenz dieser regulatorischen Aktivierung des Schlafsystems angesehen. Die Hypothese wird dann mit den vorhandenen Übersprungsverhaltenstheorien verglichen.

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The research underlying this paper has been supported by grants from the U.S. Air Force Office of Scientific Research through the European Office of Aerospace Research, the Science Research Council and the Royal Society to Professor N. Tinbergen, F. R. S. and myself. It was partly carried out at the Department of Zoology, Oxford. I am grateful to Dr. S. A. Hillyard who by revising an earlier version contributed much to whatever merits this paper has.     

A near-death experience among the Mapuche people

This paper describes a possible near-death experience (NDE) among the Mapuche people of Chile. The individual reporting the experience was in a cataleptic-like state for two days, the experience itself occurring at the end of this period. Some common features of NDEs, such as encounters with deceased people and being sent back, are present, together with clear evidence that past and present cultural environment shape in part the content of mental experiences.This work was funded in part by the University of Chile (DTI Project Q-3064).The author thanks Editorial Andrés Bello for permissionto translate the near death account into English.     

大学生镜像书写及其机制探讨

本研究选择60名右利大学生(男女各半)为被试,在笔划水平上对十四种不同书写方式下快速书写时所出现的自发性镜像书写进行了研究。所有被试随机分为人数相等的实验、对照两组,组内男女各半。对实验组加以注意干扰。书写内容是十个阿拉伯数字(0—9)及十三个汉字组成的一句话。本研究结果表明:注意干扰、感觉的反馈调节,书写内容的特点是影响镜像书写出现的重要因素。作者在分析国内外有关镜像书写工作的基础上,进一步提出了“稳态系统”理论。     

比较研究-影响中美儿童计算能力差异的认知因素

本研究要确定中美儿童基本计算技能的差异是否与他们使用的解题策略和基本加工过程的速度有关。为此,对中美两国的一年级儿童进行了书面计算能力测验,以及一组计算机呈现的加法作业。中国儿童在计算能力测验上表现出3:1的操作优势。中美儿童使用的解题策略种类一样,但是,中国儿童在策略综合运用的发展程度上超过美国儿童,检索策略的加工速度也超过美国儿童。显然,策略运用和加工速度的差异促成了中国儿童在计算能力测验上的优势.     

On becoming a leader: Effects of gender and cultural differences on power distance reduction

The present research focused on power processes in a simulated organizational structure consisting of three hierarchical levels occupied by different numbers of mules and females. Subjects were presented with a chart showing the organizational hierarchy of which they were a member placed at the lowest level, and asked to nominate any person for the leader position vacated by the current incumbent. The results of Experiment I (n = 88 Dutch male and female university students) showed that male subjects strongly overnominated themselves, whereas a majority of the female subjects nominated either self or another female. Of the others that were nominated by both males and females, almost all were occupants of positions immediately below the leader position, indicating the normative influence of a bureaucratic rule of leader succession. Experiment 2 was a replicational study carried out in a different culture (n = lOl Polish male and female university students). Polish subjects adhered to the bureaucratic rule more strongly than their Dutch counterparts, and both females and males nominated mostly males. Results are discussed with reference to gender self-stereotypes and cultural differences.     

Causation in Branching Time (I): Transitions,Events and Causes

We propose a theory of events and causes against the background of branching time. Notions discussed include possibility based on reality, transitions, events, determinacy, contingency, causes and effects. The main idea in defining causal relations is to introduce a certain preconditioning circumstance under which one event follows another. We also briefly compare this theory with some other theories.     

海马CA_3区习得性LTP的进一步探讨

分辨学习中大鼠ＰＰ－ＣＡ_３突触效应有习得性ＬＴＰ产生,进一步观察到ＭＦ－ＣＡ_３及Ｃｏｍｍ－ＣＡ_３也同步地产生习得性ＬＴＰ,表明几种输入突触都产生习得性ＬＴＰ,而ＭＦ－ＣＡ_３突触效应增强的程度则较Ｃｏｍｍ－ＣＡ_３的为大（Ｐ＜０．０１）。海马ＣＡ_３注入印防己毒素能易化ＰＰ－ＣＡ_３突触习得性ＬＴＰ的产生,工作发现一侧海马ＣＡ_３注印防己毒素,易化对侧ＭＦ－ＣＡ_３突触习得性ＬＴＰ的产生,表明两侧海马ＣＡ_３区在其习得性ＬＴＰ的形成上是相互协同的。     

乳头体对海马齿状回习得性长时程突触增强的影响

用高频电脉冲刺激大鼠乳头体（ＭＢ）,可一过性抑制由刺激穿通纤维（ＰＰ）诱发的海马齿状回（ＤＧ）群体锋电位（ＰＳ）。训练作业前先刺激ＭＢ,导致ＤＧ的习得性长时程突触增强（ＬＤＬＴＰ）的形成显著延缓,相应地延缓了条件性饮水反应的建立。电刺激ＭＢ对ＰＰ─ＤＧＰＳ的这种抑制作用在训练所产生的ＰＳ增大达最高水平时显著减弱,刺激ＭＢ对ＬＤＬＴＰ的保持及相应地对条件反应的巩固没有明显影响。结果表明ＭＢ对ＤＧＬＤＬＴＰ的形成有抑制性调制作用。     

学业不良学生类型与特点的聚类分析

该研究运用Ｑ聚类分析对上海市区１４８０名初中预备班学生的能力和个性特征进行分类研究。结果发现１４８０名被试中存有心理发展水平不同的六个主要类别,这些类别与学生学业成绩的优劣关系密切。同时,３５３名差生可分为四个主要类型：即,暂时性困难学生、能力型困难学生、动力型困难学生和整体性困难学生,不同类型的差生具有不同的特点。这为针对不同类型学生的特点制定有效的教育措施提供了依据。