雷替曲塞治疗老年晚期结直肠癌的疗效分析

比较雷替曲塞与5-氟尿嘧啶联合奥沙利铂治疗老年晚期结直肠癌的临床疗效及生存分析。经病理明确诊断的老年晚期结直肠癌患者42例分为A、B两组,分别采用雷替曲塞和5-氟尿嘧啶／亚叶酸钙联合奥沙利铂方案化疗,观察两组疗效、不良反应及生存分析。结果A、B两组患者有效率接近,无统计学差异。A、B组疾病进展时间分别是7．5个月和5．...     

Effects of self–other decision-making on time-based intertemporal choice

The effects of self–other decision-making on intertemporal choice have been revealed in many studies using a monetary outcome. However, the outcome of intertemporal choice is not restricted to money; time is also a scarce and nonrenewable resource outcome. Thus, we conducted a series of experiments to address the effects of self–other decision-making on time-based intertemporal choice, a type of intertemporal choice that uses time as an outcome. Over the course of three experiments, differences in self–other decision-making were evidenced. Participants who made decisions for others were more likely to prefer the smaller but sooner (SS) option over the larger but later (LL) option and considered the gain of the SS option to be significantly greater than that of the LL option. Participants who made decisions for themselves were likely to prefer the LL option over the SS option. However, they considered the gains of the LL and the SS option to be indifferent. Changing the role of decision-making could affect the ability of individuals to consider the future consequences of their decisions. The effects of self–other decision-making on time-based intertemporal choice could be explained by the accounts of economic reasoning and construal level theory. The findings indicated that the effects of self–other decision-making on time-based intertemporal choice, which could be generated simply by rewording questions, can help individuals make optimal long-term choices without the need for increased control.     

崇尚科学拒绝伪科学

伪科学(Pseudoscience)一词出现于1844年。我们今天称之为伪科学的许多东西在历史上与科学曾有着千丝万缕的联系,如占星术之于天文学,炼金术之于化学。但是历史上的占星术和炼金术都不是伪科学,只有在科学值得冒充之后,它们有意识地冒充科学才可算是伪科学。面对社会上的日渐泛滥的伪科学,我们不得不提高警惕,利用科学的方法揭露伪科学的真面目。我们迫在眉睫的任务是提高全民族的科学文化素质,提倡科学精神,拒绝伪科学。     

客体运动方向的视觉工作记忆容量

记忆动态场景中多客体的特征和时空信息是人类重要的认知活动。目前有关视觉工作记忆的研究虽然广泛探讨了对视觉信息的存储容量及机制,然而所采用的刺激材料均呈现于静态场景中,且不包含运动信息。而有关多客体追踪的研究只关注动态场景中多客体信息的实时更新,而不涉及一段时间内对客体信息的保持。本研究结合视觉工作记忆领域的变化觉察范式和多客体追踪范式,以独立运动的客体为刺激材料,探讨多个客体的运动方向信息在工作记忆中的存储容量问题。结果表明,在工作记忆中能够存储大约3个客体的运动方向信息。     

Mechanism underlying the self-enhancement effect of voice attractiveness evaluation: self-positivity bias and familiarity effect

The aim of the present study was to determine whether the self-enhancement effect of voice attractiveness evaluation is due to general self-positivity bias and/or the familiarity effect. The participants were asked to rate the attractiveness of their own voice, a friend's voice and strangers' voices. In addition, a self-reference valence (SR-valence) task was adopted in the experiment. Significant self-enhancement effects in voice attractiveness ratings were demonstrated, regardless of whether the participants recognized their self-voice or not. However, the friend-enhancement effect was found in only those participants who successfully recognized their friend's voice. Moreover, a significant correlation was found between self-positivity bias in the SR-valence task and the self-enhancement effect (but not the friend-enhancement effect). Our findings suggest that both the familiarity effect and self-positivity bias account for the vocal self-enhancement effect, and the influence of self-positivity bias could be implicit. The present study thus provides empirical evidence to clarify the potential explanations for the self-enhancement of voice attractiveness assessment.     

音乐对希望感的影响

过去的研究发现,在经历挫折后,相比于不听音乐,听积极音乐能提升人们的希望感。然而,研究者并不清楚积极音乐和消极音乐在提升希望感上是否存在差异,也不清楚这种差异是否由于两种音乐在诱发的积极情绪或消极情绪的差异造成的。文章通过三个实验来考察这些问题。实验一发现,在无挫折的情况下,积极音乐相比消极音乐诱发了更强的希望感。实验二发现,这种效应同样存在于人们回忆挫折之后,并且是积极情绪在其中起中介作用。实验三则通过设置控制组进一步发现,这种效应是由积极音乐对希望感的提升作用和消极音乐对希望感的降低作用共同引起的。文末讨论了该发现的意义。     

Outliers and Influential Observations in Exponential Random Graph Models

We discuss measuring and detecting influential observations and outliers in the context of exponential family random graph (ERG) models for social networks. We focus on the level of the nodes of the network and consider those nodes whose removal would result in changes to the model as extreme or “central” with respect to the structural features that “matter”. We construe removal in terms of two case-deletion strategies: the tie-variables of an actor are assumed to be unobserved, or the node is removed resulting in the induced subgraph. We define the difference in inferred model resulting from case deletion from the perspective of information theory and difference in estimates, in both the natural and mean-value parameterisation, representing varying degrees of approximation. We arrive at several measures of influence and propose the use of two that do not require refitting of the model and lend themselves to routine application in the ERGM fitting procedure. MCMC p values are obtained for testing how extreme each node is with respect to the network structure. The influence measures are applied to two well-known data sets to illustrate the information they provide. From a network perspective, the proposed statistics offer an indication of which actors are most distinctive in the network structure, in terms of not abiding by the structural norms present across other actors.     

<Emphasis Type="Italic">Wh</Emphasis>-Questions,Universal Statements and Free Choice Inferences in Child Mandarin

This study investigated 5-year-old Mandarin-speaking children’s comprehension of wh-questions, universal statements and free choice inferences. Previous research has found that Mandarin-speaking children assign a universal interpretation to sentences with a wh-word (e.g., shei ‘who’) followed by the adverbial quantifier dou ‘all’ (Zhou in Appl Psycholinguist 36:411–435, 2013). Children also compute free choice inferences in sentences that contain a modal verb in addition to a wh-word and dou (Zhou, in: Nakayama, Su, Huang (eds.) Studies in Chinese and Japanese language acquisition: in honour of Stephen Crain. John Benjamins Publishing Company, Amsterdam, pp 223–235, 2017). The present study used a Question-Statement Task to assess children’s interpretation of sentences containing shei + dou, both with and without the modal verb beiyunxu ‘was allowed to’, as well as the contrast between sentences with shei + dou, which are statements for adults, versus ones with dou + shei, which are wh-questions for adults. The 5-year-old Mandarin-speaking child participants exhibited adult-like linguistic knowledge of the semantics and pragmatics of wh-words, the adverbial quantifier dou, and the deontic modal verb beiyunxu.     

Differences in Scope Assignments for Child and Adult Speakers of Mandarin

The present study used a Truth Value Judgment Task to investigate whether changes in sentence structure lead to corresponding changes in the assignment of scope relations by Mandarin-speaking children and adults. In one condition, participants were presented with ordinary negative sentences containing disjunction; this condition was designed to verify the existing claim that disjunction is a positive polarity item for adult speakers of Mandarin, but not for child speakers. In a second condition, participants were presented with negative sentences where the disjunction phrase was preposed from object position; this condition was designed to examine the extent to which changes in sentence structure can result in changes in scope assignments to negated disjunctions. The results indicate that the preposed disjunction phrase undergoes reconstruction for children, whereas reconstruction is blocked for adults. This finding also suggests that Mandarin-speaking children and adults exhibit different scope preferences for negated disjunctions, regardless of where the disjunction phrase appears in the surface syntax.