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生态危机的化解需要宗教的参与,"道教生态学"的兴起便是宗教回应生态危机的积极成果.道教凭借其"道法自然"、"贵生恶死"、"天人互盗"等思想观点,在处理人与自然关系方面积累了丰富的生态智慧.因此,充分发掘道教的生态思想,对于丰富和发展生态学研究具有重要意义. 相似文献
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The perforant path projecting from the entorhinal cortex to the hippocampal dentate gyrus is a particularly vulnerable target to the early deposition of amyloid beta (Abeta) peptides in Alzheimer's brain. The authors previously showed that brief applications of Abeta at subneurotoxic concentrations suppressed the early-phase long-term potentiation (E-LTP) in rat dentate gyrus. The current study further examines the effect of Abeta on the late-phase LTP (L-LTP) in this area. Using multiple high-frequency stimulus trains, a stable L-LTP lasting for at least 3 h was induced in the medial perforant path of rat hippocampal slices. Bath application of Abeta(1-42) (0.2-1.0 microM) during the induction trains attenuated both the initial and late stages of L-LTP. On the other hand, Abeta(1-42) perfusion within the first hour following the induction primarily impaired the late stage of L-LTP, which resembled the action of the protein synthesis inhibitor emetine. Blockade of calcineurin activity with FK506 or cyclosporin A completely prevented Abeta-induced L-LTP deficits. These results suggest that Abeta(1-42) impaired both the induction and maintenance phase of dentate L-LTP through calcineurin-dependent mechanisms. In the concentration range effective for inhibiting L-LTP, Abeta(1-42) also reduced the amplitude of NMDA receptor-mediated synaptic currents in dentate granule cells via a postsynaptic mechanism. In addition, concurrent applications of Abeta(1-42) with the protein synthesis inhibitor caused no additive reduction of L-LTP, indicating a common mechanism underlying the action of both. Thus, inhibition of NMDA receptor channels and disruption of protein synthesis were two possible mechanisms contributing to Abeta-induced L-LTP impairment. 相似文献
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Qiang Xie Ye Guan Stefan G. Hofmann Ting Jiang Xinghua Liu 《Scandinavian journal of psychology》2023,64(1):21-29
The benefits of mindfulness-based interventions to alleviate anxiety and depression have been supported by many studies. Given the effectiveness of mindfulness-based interventions on anxiety and depression, the underlying mechanisms need to be explored. Using a randomized waitlist-controlled design, this study investigated whether anxiety sensitivity was a potential mechanism for the impact of mindfulness training on anxiety and depression. Participants with high psychological distress were randomly assigned to an eight-week mindfulness intervention (N = 35) or a wait-list control group (N = 34). Before and after the intervention or corresponding waitlist period, participants completed measures of anxiety and depression severity and impairment and anxiety sensitivity. Separate mixed ANOVA demonstrated significant group (intervention vs. control group) × time (pre- vs. post-test) interactions for anxiety sensitivity and overall anxiety severity and impairment and marginally significant interaction for overall depression severity and impairment. Moreover, simple mediation models showed that reductions of anxiety sensitivity from pre- to post-test mediated the impact of mindfulness training on changes in anxiety and depression severity and impairment. The findings suggest that anxiety sensitivity is a potential mechanism underlying the effect of mindfulness training on anxiety and depression, which provides a new perspective for the study of processes of change of mindfulness-based interventions. 相似文献
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以一位第一次进行胼胝体前部切开,第二次作后部切开的胼胝体全切断患者为被试,在第二次手术前后进行了Ⅰ。左右单侧操作检查,和Ⅱ。两半球之间感觉信息传递两类神经心理学实验。结果提示:后部切断前,左右侧操作没有明显的差异。同时,视觉和触觉的感觉信息的传递基本正常。在后部切断后,命名作业呈右视野和右手优势,图形临摹左手似乎较好,这时视觉和触党的感觉信息的传递发生了障碍。左视野和左手命名高于随机水平,讨论了这一结果与右脑语言的关系。方位比较等多个实验提供了支持两半球协同活动理论的证据。 相似文献
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Current Psychology - Whether transactive memory system can improve top management team’s creativity is an important issue that remains to be solved. Based on the theory of information... 相似文献
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对15种测验等值方法的比较研究 总被引:20,自引:2,他引:18
此项研究通过试验方法对4种基于经典测验理论的等值方法和11种基于项目反应理论的等值方法进行了比较研究。研究数据为HSK正式考试的数据,研究采用了较为可靠的检验标准。研究结果表明,在有些情况下,进行等值处理并非是最好的选择;在题库建设中,某些IRT方法是可行的;至少对于HSK数据,不论是单、双、三参数,不论是ms方法和mm方法,IRT参数转换等值方法的误差都较大,均不足取。 相似文献